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InSite Vision Company Profile

20:21 EDT 19th September 2017 | BioPortfolio

InSite Vision is an ophthalmic products company currently focused on ocular infection, glaucoma, and retinal disease. The Company specializes in three platform technologies: topical drug delivery (DuraSite), genomics, and retinal drug delivery. As a result, the Company has a portfolio of both diagnostic and therapeutic products in early and late-stage development. The Company's lead product, AzaSite™, targets infection of the eye, and will initially compete in the expanding market for ocular infection in the United States. AzaSite contains the drug azithromycin, a widely used, broad-spectrum antibiotic that has now been successfully formulated for topical application in the eye. AzaSite is formulated with DuraSite®, InSite Vision's patented drug-delivery vehicle, which offers the prolonged release of an active ingredient. This formulation could offer the benefit of a low-dosing regimen, attractive to both the eye-care patient and physician. The Company filed a New Drug Application in June 2006 and expects Inspire Pharmaceuticals, the AzaSite licensee for the U.S. and Canada, to commercially launch AzaSite in the United States in the second half of 2007. The Company also plans to pursue AzaSite license agreements outside of the United States during the second half of 2007. In the area of glaucoma, the Company conducts genomic research using the TIGR/MYOC gene, among other genes in the existing research/development portfolio. A portion of this research has been incorporated into the Company's OcuGene glaucoma genetic test for disease management. The commercially available OcuGene® test is a genetically based prognostic tool designed to detect a genetic marker (mt-1) in the promoter region of the glaucoma-related TIGR gene. Eye care specialists who utilize this test may gain valuable insight regarding disease management options, in combination with other risk factor data, before irreversible clinical changes become obvious, leading to diminished visual capability. Genomic research has also supported the development of ISV-205, the Company's novel glaucoma therapeutic. The ISV-205 formulation utilizes the DuraSite drug-delivery technology, and contains the drug diclofenac. The ISV-205 product candidate delivers concentrations of diclofenac that have been shown in cell culture systems to inhibit the production of the TIGR protein. Phase 2b clinical studies were successfully completed in 2001, and further development requires additional funding or collaboration with a strategic partner. Retinal development candidates include an intra-scleral delivery system device, represented as ISV-014. This device allows for the controlled and minimally invasive delivery of ophthalmic drugs to the retina and other tissues in the posterior chamber of the eye. The development of new opportunities related to the preservation and improvement of sight are directly associated with the Company's Mission and Vision Statement, designed to guide the activities and future direction of the organization.

Location

965 Atlantic Avenue
Alameda
CA
94501
United States of America

Contact

Phone: 510 865 8800
Fax: 510 865 5700
Email: KumarCh@insite.com


News Articles [448 Associated News Articles listed on BioPortfolio]

Laying the foundation for a lifetime of eye health

After life itself, it is said that God’s great gift is vision. 80 percent of what we learn is through vision. Babies are not born with perfect vision. They develop vision over time. A child who neve...

Multifocal IOL on toric platform improves near, intermediate vision

LOS ANGELES — Adding a toric platform to a multifocal IOL significantly improves vision at intermediate and near distances, according to one speaker. “Our goal was to show that, if you put the tor...

4 M€ de plus pour Pixium Vision

Tous les jours un bref écho des principales infos de la veille pour les biotechs francophones avec le remindHIER de BiotechFinances.  Pixium Vision (FR0011950641 – PIX), systèmes de vision ...

Patient gets ‘bionic eye’ vision system during retinal implant

More than two decades ago, doctors could do nothing for Walfre Lopez as his vision faded away due to a degenerative eye disease. Now, a revolutionary artificial-vision procedure done at University of ...

LCA-Vision to Present at the Lazard Capital Markets 9th Annual Healthcare Conference

CINCINNATI, Nov. 7, 2012 /PRNewswire/ -- LCA-Vision Inc. (NASDAQ: LCAV), a leading provider of laser vision correction services under the LasikPlus® brand, today announced that management wi...

Vision on the Horizon: Horizon Pharma acquires River Vision’s Thyroid Eye Disease mAb

Horizon Pharma has announced it will acquire River Vision Development Corp. and its fully human monoclonal antibody (mAb), teprotumumab (RV001).

For people with Down syndrome, varying test results can make it harder to get the right vision prescription

Even objective, automated vision testing—using a device called an autorefractor—gives variable results in patients with Down syndrome, reports a study in the May issue of Optometry and Vision Scie...

Peek into your genes: NASA one-year mission investigators identify links to vision problems

(NASA/Johnson Space Center) Coinciding with May -- Healthy Vision Month, NASA's One-Year Mission investigators are peering into their new findings to help address astronaut vision issues.

Drugs and Medications [9 Associated Drugs and Medications listed on BioPortfolio]

Besivance [Bausch & Lomb Incorporated]

These highlights do not include all the information needed to use Besivance safely and effectively. See full prescribing information for Besivance. Besivance (besifloxacin ophthalmic suspension) 0.6%S...

Besivance [Physicians Total Care, Inc.]

These highlights do not include all the information needed to use Besivance safely and effectively. See full prescribing information for Besivance. Besivance (besifloxacin ophthalmic suspension) 0.6%S...

Soothe xp [Baush & Lomb Incorporated]

Drug Facts

Carboxymethylcellulose sodium [PROMED EXPORTS PRIVATE LIMITED]

Sterile isotonic buffered genuine eyewash [Genuine First Aid]

Sterile Isotonic Buffered Genuine Eyewash

PubMed Articles [448 Associated PubMed Articles listed on BioPortfolio]

Vision Screening in Children Aged 6 Months to 5 Years: Evidence Report and Systematic Review for the US Preventive Services Task Force.

Preschool vision screening could allow detection and treatment of vision abnormalities during a critical developmental stage, preserving function and quality of life.

Vision Screening in Children Aged 6 Months to 5 Years: US Preventive Services Task Force Recommendation Statement.

One of the most important causes of vision abnormalities in children is amblyopia (also known as "lazy eye"). Amblyopia is an alteration in the visual neural pathway in a child's developing brain that...

To See Anew: New Technologies Are Moving Rapidly Toward Restoring or Enabling Vision in the Blind.

Humans have been using technology to improve their vision for many decades. Eyeglasses, contact lenses, and, more recently, laser-based surgeries are commonly employed to remedy vision problems, both ...

The visual and haptic contributions to hand perception.

Previous research has found that the perception of our hands is distorted. The characteristics of this distortion are an overestimation of hand width and an underestimation of finger length. The prese...

Scene perception from central to peripheral vision.

Clinical Trials [574 Associated Clinical Trials listed on BioPortfolio]

Low-vision Rehabilitation Program for Low-vision Patients and Care Givers

To evaluate health related quality of life (HRQoL) of low-vision patients and their care givers undergoing low-vision rehabilitation program (LVRP).

Low Vision Intervention Trial II (LOVIT II)

This study will determine if the interdisciplinary team low vision rehabilitation program is more effective than basic low vision care provided by an optometrist working alone in improving...

Safety Study Looking at the Effects of Stendra on Vision

The purpose of this study is to see if Stendra causes any changes in vision, eye pressure, pupil dilation, and color vision in healthy males.

VA Low Vision Intervention Trial

The primary purpose of this research study is to evaluate the effectiveness of a new outpatient low vision rehabilitation program that is targeted to serve legally blind veterans with cent...

Retina Projection System Trials for Low Vision People

1. Purpose a. Examination on Efficacy of Retina Projection System 2. Patients a. Low vision patients 3. Methods 1. Vision aids ...

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InSite Vision is committed to advancing new and superior ophthalmologic products for unmet eye care needs. InSite Vision is recognized for the discovery and development of novel o...

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Insite Security specializes in personal security for high net worth individuals as well as large national and multi-national corporations. The company regularly consults with Fortune 1000 companies an...

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InSite One, Inc.

For more than a decade, InSite One, Inc. has distinguished itself as the market leader in medical data archiving, disaster protection and storage content management services and was the first to offer...

More Information about "InSite Vision" on BioPortfolio

We have published hundreds of InSite Vision news stories on BioPortfolio along with dozens of InSite Vision Clinical Trials and PubMed Articles about InSite Vision for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of InSite Vision Companies in our database. You can also find out about relevant InSite Vision Drugs and Medications on this site too.

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