Pain Therapeutics Company Profile

12:39 EDT 20th September 2017 | BioPortfolio

Pain Therapeutics, Inc. is a medical research company whose mission is to develop a new generation of opioid drugs (‘narcotic painkillers’). PTI has five active INDs and is focusing its Phase II development efforts on two lead compounds:

MorViva™ - a substitute for morphine and other strong opioids, and

OxyTrex™ - a substitute for oxycodone and other moderately strong opioids

The Company has two additional drug candidates, PTI-601 and PTI-701, which are also being developed.

An opioid drug (sometimes called a ‘narcotic painkiller’) refers to any drug that is derived from the opium poppy plant. This class of drugs is widely used throughout the world to treat clinical pain. In the U.S., for example, the market for narcotic painkillers exceeded $3 billion and accounted for over 5 percent of all prescription drug sales in the year 2001.

Despite widespread clinical use of narcotic painkillers, the under-treatment of pain is a serious and growing problem. For example, according to the National Institutes of Health, over 40 million Americans are unable to find relief from their pain. Conventional narcotic painkillers have debilitating side effects that limit their usefulness at all doses. In addition, chronic use of conventional narcotic painkillers may lead to tolerance, dependence, abuse, or, very rarely, addiction. As a result, some patients prefer to suffer through pain rather than to endure the ill effects of conventional narcotic painkillers.


416 Browning Way
San Francisco
United States of America


Phone: 650-624-8200
Fax: 650-624-8222

News Articles [3121 Associated News Articles listed on BioPortfolio]

NIH grants $4M to Pain Therapeutics for Alzheimer's blood test, fentanyl patch

The NIH awarded a $4 million grant to Pain Therapeutics to support the company's development of an Alzheimer's disease blood  -More- 

STAT Plus: Nektar Therapeutics reports progress in making an opioid pain pill that addicts don’t much like

A novel opioid from Nektar Therapeutics crosses the blood-brain barrier slowly, so it relieves pain but is harder to abuse.Trial results are promising.

STAT Plus: Nektar Therapeutics reports progress in making an opioid pain pill that drug users don’t much like

A novel opioid from Nektar Therapeutics crosses the blood-brain barrier slowly, so it relieves pain but is harder to abuse.Trial results are promising.

Antibe Therapeutics Inc., Safe Pain and Inflammation Medicine, CEO Clip Video

Vancouver, British Columbia--(Newsfile Corp. - September 13, 2017) - Dan Legault, CEO of Antibe Therapeutics Inc., on the company's best-in-class pain/inflammation and regenerative medicine divisio...

Cara Therapeutics' Phase 3 Trial Will Continue, Studies Postoperative Pain Treatment

NewsCara Therapeutics reports continuation of Phase 3 trial of I.V. CR845 in postoperative pain following interim assessment.

Centrexion Therapeutics to Present at the Jefferies 2017 Global Healthcare Conference

Centrexion Therapeutics, a company focused on advancing the treatment of chronic pain with one of the largest exclusively pain-focused pipelines of non-opioid therapies in acti...

Cara Therapeutics to Present at the 17th Annual Conference on Pain Therapeutics

Dr. Joseph Stauffer to deliver opening remarks and discuss kappa opioid receptor agonists as a novel approach to acute and chronic pain managementDr. Stauffer serves as co-chair and on the event’...

2 contrasting medtech approaches to deal with chronic pain and avoid opioids

Medtronic and SPR Therapeutics are treating chronic pain but while the former has adopted a permanent, implantable neuromodulation treatment, the latter is going the temporary wearable route.

PubMed Articles [3153 Associated PubMed Articles listed on BioPortfolio]

Progress and challenges in the optimization of toxin peptides for development as pain therapeutics.

The number of new toxin peptide discoveries has been rapidly growing in the past few decades. Because of progress in proteomics, sequencing technologies, and high throughput bioassays, the search for ...

Increased deep pain sensitivity in persistent musculoskeletal pain but not in other musculoskeletal pain states.

Pressure pain thresholds (PPTs) in a non-painful body area are known to be affected in some chronic pain states. The aim of this study is to investigate PPTs in a pain-free body part in relation to pa...

Moving beyond pain scores: Multidimensional pain assessment is essential for adequate pain management after surgery.

Clinical experience teaches us that patients are willing to accept postoperative pain, despite high pain intensity scores. Nevertheless, relationships between pain scores and other methods of pain ass...

Prospective Assessment of Pain and Comfort in Chronic Pain Patients Undergoing Interventional Pain Management Procedures.

 Interventional pain management procedures have an important role in the management of chronic pain. The present study seeks to identify the proportion of patients who experience severe pain during ...

Ultrasound Assessment of Abdominal Muscle Thickness in Women With and Without Low Back Pain During Pregnancy.

The aim of this preliminary study was to determine the differences in abdominal musculature thickness, within 1 month of delivery, in women who experienced back pain during pregnancy compared with tho...

Clinical Trials [4623 Associated Clinical Trials listed on BioPortfolio]

Impact of Ibis on Patients With Advanced COPD

The purpose of this research is to determine if Ibis™, a digital therapeutics solution developed by Senscio Systems, reduces the emergency room visits and hospitalizations of patients wi...

Interest of Pain Assessment by the Family of Patients in Limiting and Stopping Active Treatment Process Admitted in ER. Study DOFAMILA

Decisions to limit and stop active therapeutics are common in the emergency unit. They are framed by the Leonetti law of 22 April 2005 recommending the refusal of unreasonable obstinacy an...

HDL Acute Lipid Optimization in Homozygous Familial Hypercholesterolemia

Assess the effect on coronary atheroma of serial infusions of autologous selectively delipidated HDL/preβ enriched plasma following use of HDL Therapeutics PDS-2™ System

Ontogenesis of the P-Glycoprotein in Human Lymphocytes Influence of HIV and Antiretroviral Therapeutics

The P-glycoprotein (P-gp) is a membranous transporter that modulates the intracellular concentrations of many drugs and plays thus a major role in the efficacy of the therapeutics that act...

A Trial to Find Safe and Active Doses of an Investigational Drug CX-072 for Patients With Solid Tumors or Lymphomas

The purpose of this first-in-human study of CX-072 is to characterize the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and antitumor activity of CX-072 administered i...

Companies [1668 Associated Companies listed on BioPortfolio]

Centrexion Therapeutics

Centrexion Therapeutics, Inc., is focused on developing and commercializing new, non-opioid and non-surgical treatments for moderate to severe chronic pain. Centrexion Therapeutic...

Centrexion Therapeutics, Corp.

Centrexion Therapeutics, Corp. is focused on advancing the treatment of chronic moderate to severe pain with one of the largest exclusively pain-focused pipelines of non-...

CNS Therapeutics

Founded in 2007 by recognized experts in intrathecal drug therapies, CNS Therapeutics is a private company based in St. Paul, Minnesota. CNS Therapeutics develops and markets safe...

Algos Therapeutics, Inc

Algos Therapeutics is a privately held, independent research company specializing in the evaluation of potential pain treatments under development. The data we generate from our models have proven hig...

The Rosomoff Comprehensive Pain Center (RCPC)

The Rosomoff Comprehensive Pain Center (RCPC) is a state-of-the-art Center of Excellence offering inpatient, outpatient, outpatient rehabilitation services and seniors programs. Founded in 1974 as the...

More Information about "Pain Therapeutics" on BioPortfolio

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Pain is defined by the International Association for the Study of Pain as “an unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in terms of such damage”. Some illnesses can be excruci...

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