PathoGenesis Corporation Company Profile

12:00 EDT 24th September 2017 | BioPortfolio

PathoGenesis Corporation develops and markets novel drugs to treat serious, chronic human infectious diseases where there is a significant need for improved therapy. In December 1997, the U. S. Food and Drug Administration approved ourfirst drug, TOBI (tobramycin solution for inhalation). TOBI is indicated for the management of cystic fibrosis (CF) patients with Pseudomonas aeruginosa lung infections. PathoGenesis Corporation began marketing TOBI in 1998 in the U.S., and generated $60.7 million in sales during the year. TOBI was approved for sale in Canada and Argentina in February 1999. PathoGenesis Corporation have filed for regulatory approvals in Europe and Australia. Applications in other countries are pending.


201 Elliott Avenue W. Suite 150
United States of America


Phone: 206 467 8100
Fax: 206 270 3313

News Articles [137 Associated News Articles listed on BioPortfolio]

The case for periodontitis in the pathogenesis of rheumatoid arthritis

The amount of clinical, serological and experimental evidence linking periodontitis to rheumatoid arthritis is constantly increasing. In this Review, Potempa and colleagues lay out the case for period...

New biomarkers of multiple sclerosis pathogenesis

(Kazan Federal University) Multiple sclerosis (MS) is a chronic debilitating inflammatory disease targeting the brain. The pathogenesis of MS remains largely unknown. It is believed that brain tissue ...

Molecular Pathogenesis of Progressive Lung Diseases

Molecular Pathogenesis of Progressive Lung Diseases Author: Larry H. Bernstein, MD, FCAP   Abstract The lung and its airways are constantly exposed to the air we breath, its contaminants, micropa...

Perianal fistulizing Crohn's disease: pathogenesis, diagnosis and therapy

Perianal fistulizing Crohn's disease has a major negative effect on a patient's quality of life and is a predictor of poor long-term outcome. Here, the authors provide an up-to-date overview on the pa...

#jobs #lifescience University of California, Irvine: Postdoctoral Scholar- Microbial Pathogenesis

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: University of California, Irvine: Postdoctoral Scholar- Microbial Pathogenesi...

Intrinsic4D Inc. Announces Public Sale of Substantially all of the Assets of its Operating Subsidiary and Transfer to NEX

TORONTO, ONTARIO -- (Marketwired) -- 05/11/17 -- Intrinsic4D Inc. (the "Corporation") (TSX VENTURE: IFD) provides stakeholders with an update in relation to its financial status and solvency. Publi...

[Comment] Interleukin 23 inhibitors for psoriasis: not just another number

Major advances have been made in the past 30 years in elucidating the pathogenesis of psoriasis, including the identification of T-helper 17 (Th17) lymphocytes as key players in psoriatic inflammation...

Viral pathogenesis: Finding the enemy within

PubMed Articles [676 Associated PubMed Articles listed on BioPortfolio]

Role of HLA-B27 in the pathogenesis of ankylosing spondylitis (Review).

The study of ankylosing spondylitis (AS) has made significant progress over the last decade. Genome-wide association studies have identified and further substantiated the role of susceptibility genes ...

Astrovirus Pathogenesis.

Astroviruses are a major cause of diarrhea in the young, elderly, and the immunocompromised. Since the discovery of human astrovirus type 1 (HAstV-1) in 1975, the family Astroviridae has expanded to i...

Atopic dermatitis: pathogenesis.

Atopic Dermatitis (AD) is a complex inflammatory cutaneous disorder characterized by immune mediated inflammation and epidermal barrier dysfunction. Arising from a complex interplay between environmen...

Genetics of Alzheimer's disease: From pathogenesis to clinical usage.

Alzheimer's disease (AD) is the most common type of dementia and has caused a major global health concern. Understanding the etiology of AD can be beneficial for the diagnosis and intervention of this...

The Role of Gut Microbiome in the Pathogenesis of Prostate Cancer: a Prospective, Pilot Study.

To elucidate potential biomarkers or mechanistic principles involved with the gut microbiota and its impact on prostate cancer pathogenesis.

Clinical Trials [474 Associated Clinical Trials listed on BioPortfolio]

Adrenal Tumors - Pathogenesis and Therapy

The pathogenesis of adrenal tumors is still not fully elucidated and the treatment options for malignant tumors are poor. The current study investigates different aspects of the pathogenes...

Pathogenesis of Primary Spontaneous Pneumothorax

Primary spontaneous pneumothorax most commonly occurs in young, tall, lean males. The estimated recurrence rate is 23-50% after the first episode and increases to 60% after the second pneu...

HIV Diversity and Pathogenesis in Donor-Recipient Clusters

To assess, in donor-recipient clusters, current models of HIV-1 genetic evolution and pathogenesis, based on the sequence diversity displayed by this lentivirus.

The Scleroderma Biorepository and Pathogenesis Study (STOP Scleroderma)

The Scleroderma bioreposiTOry and Pathogenesis Study (STOP Scleroderma) will help researchers use clinical data and human biospecimens to investigate why scleroderma patients develop certa...

Efficacy and Safety of Belimumab in Subjects With Primary Sjögren's Syndrome

Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by an increase in BAFF (BLyS) levels and a resulting B cell hyperactivity. B cells are involved in the pathogenesis ...

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PathoGenesis Corporation develops and markets novel drugs to treat serious, chronic human infectious diseases where there is a significant need for improved therapy. In December 1997, the U. S. Food ...

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