Steroidogenesis Inhibitors International Company Profile

18:19 EDT 25th September 2017 | BioPortfolio

Drug Discovery


2001 East Flamingo Boulevard Suite 100B
Las Vegas
United States of America


Phone: 702 735 7001
Fax: 702 737 7016

News Articles [1006 Associated News Articles listed on BioPortfolio]

Novel therapy decreases incidence of bleeding by 87% in hemophilia A patients with inhibitors

An international team of hematologists including Guy Young, MD, of Children's Hospital Los Angeles, has found that in patients with hemophilia A with inhibitors, a novel therapy called emicizumab, dec...

HIV Drug Market by Medication class multiclass combination drugs, nucleoside reverse transcriptase inhibitors NRTIs, nonnucleoside reverse transcriptase inhibitors NNRTIs, protease inhibitors PIs, fusion inhibitors FI, entry inhibitors, and HIV integrase

Human Immunodeficiency Virus Hiv Attacks The Bodys Immune System, Making The Host System Susceptible To Infection, And Thus Leading To Complete Damage. The Virus Attacks The Cd4 Cells, Which Help The ...

Study Warns of Diabetic Ketoacidosis With SGLT2 Inhibitors in T2D (CME/CE)

(MedPage Today) -- Doubled risk compared with DPP4 inhibitors

SGLT2 Inhibitors Double the Risk for Diabetic Ketoacidosis

The risk for diabetic ketoacidosis is roughly twofold for type 2 diabetes patients initiating SGLT2 inhibitors compared with DPP-4 inhibitors, but the overall absolute risk remains low. Medscape Me...

Study Confirms Link Between SGLT2 inhibitors and Diabetic Ketoacidosis

WEDNESDAY, June 7, 2017 -- A new class of type 2 diabetes drugs called SGLT2 inhibitors could increase the risk of a rare, life-threatening complication of the disease called ketoacidosis, a new study...

Prolonged use of cancer inhibitors can lead to severe cardiovascular problems

Plk1 inhibitors have recently been acknowledged as an "Innovative Therapy for leukaemia" by the US Food and Drug Administration.

Preoperative Administration of ACE Inhibitors or ARBs

This commentary explores the considerable controversy regarding the safety of administering ACE inhibitors or angiotensin II receptor blockers prior to non-cardiac surgery. Anesthesiology

New Drug Classes for Diabetes Mean New Options

Dr Cyrus Desouza reviews GLP-1 receptor agonists, DPP-4 inhibitors, and SGLT2 inhibitors, offering advice on which patients may benefit from each class. Endocrine Society

Drugs and Medications [437 Associated Drugs and Medications listed on BioPortfolio]

Pvp iodine prep pad [Professional Disposables International, Inc.]

Drug Facts

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PubMed Articles [3163 Associated PubMed Articles listed on BioPortfolio]

Neglected issues concerning teaching human adrenal steroidogenesis in popular biochemistry textbooks.

In the human body, the adrenal steroids collectively regulate a plethora of fundamental functions, including electrolyte and water balance, blood pressure, stress response, intermediary metabolism, in...

NF-κB-vimentin is involved in steroidogenesis stimulated by mono-butyl phthalate in primary cultured ovarian granulosa cells.

Di-n-butyl phthalate (DBP) and its active metabolite, monobutyl phthalate (MBP) are the most common endocrine disrupting chemicals. Many studies indicated the effects of MBP on male steroidogenesis, h...

Structure-based optimisation of non-steroidal cytochrome P450 17A1 inhibitors.

Five new non-steroidal inhibitors for cytochrome P450 17A1 (CYP17A1) were identified by structure-based optimisation from a recently identified selective CYP17A1 inhibitor. The compounds are nanomolar...

SAVE-AMD: Safety of VEGF Inhibitors in Age-Related Macular Degeneration.

To determine whether intraocular treatment with vascular endothelial growth factor (VEGF) inhibitors change systemic endothelial function (EF) in patients with neovascular age-related macular degenera...

Supplementation with dietary linseed oil during peri-puberty stimulates steroidogenesis and testis development in rams.

Omega-3 polyunsaturated fatty acids (ω-3 PUFAs), such as α-linolenic acid (ALA), eicosapentaenoic acid, and docosahexaenoic acid, are involved in male reproductive function. In this study, we invest...

Clinical Trials [1731 Associated Clinical Trials listed on BioPortfolio]

Human Chorionic Gonadotropin Stimulation Effects on Steroidogenesis in Men With Klinefelter Syndrome

The study design included six visits. During the first visit (visit 0), the subjects underwent physical examination(height, weight, body mass index (BMI), arm span, and upper segment measu...

The Malmö International Brother Study (MIBS)

Existing data support the concept that a genetic predisposition for inhibitor development exists. The aim of the Malmö International Brother Study (MIBS) is to evaluate genetic factors a...

Genetic Susceptibility to Factor VIII Inhibitors

This international study will identify genetic factors that may influence the development of inhibitory antibodies in patients with hemophilia A after treatment with factor VIII. Bleeding ...

Effects of Achieving Very Low LDL-Cholesterol After Treatment With Statins on Steroidogenesis and Cognition

We aimed to compare the effect of achieving an LDL-cholesterol

Effect of Aromatase Inhibitors on Bones and Genes

The primary objective of this 2-year pilot project is to test the hypothesis that skeletal response to aromatase inhibitors is determined by polymorphisms of the CYP19 gene.

Companies [1376 Associated Companies listed on BioPortfolio]

Steroidogenesis Inhibitors International

Drug Discovery

Amura Holdings Ltd

Amura has two complementary technology platforms which enable rapid and innovative drug discovery. AMcore™, the bicyclic core molecular scaffold chemistry and the computational screening and design...

Viamet Pharmaceuticals, Inc.

Viamet discovers and develops novel inhibitors of key metalloenzymes via an innovative and proprietary metal-binding approach, the Metallophile™ Technology. Viamet’s dis...

Amura Therapeutics Ltd

Amura has two complementary technology platforms which enable rapid and innovative drug discovery. AMcore™, the bicyclic core molecular scaffold chemistry and the computational screening and design...

KalVista Pharmaceuticals, Inc.

KalVista Pharmaceuticals, Inc. is a pharmaceuticals company focused on the discovery, development, and commercialization of small molecule protease inhibitors for diseases with si...

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