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TopoTarget and CuraGen Announce Initiation of NCI-sponsored Phase II Clinical Trial with PXD101 for MesotheliomaTopoTarget A/S and CuraGen Corporation announced today the initiation of patient dosing in a Phase II clinical trial evaluating the activity of PXD101, a small molecule histone deacetylase (HDAC) inhibitor, for the treatment of mesothelioma. This trial is being sponsored by the National Cancer Institute (NCI) under a Clinical Trials Agreement.
The Phase II clinical trial is an open-label study being led by Suresh Ramalingam, M.D., Assistant Professor of Medicine at the University of Pittsburgh School of Medicine, in Pittsburgh, PA, USA. Patients with unresectable malignant pleuralm esothelioma, w,ho have failed one prior line of chemotherapy, will be enrolled and receive PXD101by intravenous infusion every three weeks. The primary endpoint for the study is response rate, with secondary endpoints evaluating safety and measuring both the time to treatment failure and survival. A total of approximately 37 patients are expected to be enrolled into this study at multiple sites across the United States.
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Authorities in Denmark have put together a program designed to allay patient’s concerns over switching…
Congenital toxoplasmosis – an infection passed on from mother to fetus – has a high disease burden per case. However, only a relatively small number of cases occur each year in Denmark. This is th...
REYKJAVIK, Iceland ― Denmark’s biggest company is selling off the country’s last oil firm as the world’s top wind turbine-producing nation transitions to renewable energy.
REYKJAVIK, Iceland ― Denmark, the world’s top wind turbine producer, is selling off its last oil company.
A fourth batch of Janssen-Cilag’s schizophrenia drug Xeplion has been withdrawn in Denmark after the identification of counterfeit packs.
Environmental campaigners on Wednesday urged the EU to take action against Denmark, accusing officials there of facilitating the traditional annual hunt of pilot whales in the Faroe Islands.
Two more tonnes of insecticide-contaminated eggs have been discovered in Denmark, bringing the country's total to 22 tonnes, the Danish Veterinary and Food Administration said Friday.
(BBC) – Denmark has pledged more funds for family planning in developing nations, saying this could also help “limit the migration pressure on Europe”. The Minister for Development C...
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On July 22, 2011, Anders Breivik killed 77 adults and children in Norway. Having recently documented increases in the incidence of trauma- and stressor-related disorders in Denmark after the 9/11 atta...
To describe nepafenac use in the Netherlands and Denmark with reference to its approved indications. For context, we also describe the use of ketorolac and diclofenac.
Bariatric surgery offers effective obesity treatment. The aim of this study was to evaluate the cost-effectiveness of bariatric surgery in Denmark from a third-party payer perspective in the mid- (ten...
Congenital toxoplasmosis (CT) causes a substantial disease burden worldwide. The aim of this study was to estimate the disease burden of CT in Denmark, a developed country with free public healthcare ...
This study compares handgrip strength and its association with mortality across studies conducted in Moscow, Denmark, and England.
This study aims to investigate current aftercare activities in Denmark after intensive care unit (ICU) treatment. The hypothesis is that a large number of hospitals offer aftercare, and th...
The study is a epidemiological, cross-sectional study in a mainly rural area of Denmark in Denmark. Life expectancy is shorter, morbidity is higher, and social problems more prevalent than...
Aim The aim of this study is to determine consequences at school age of the diagnosis of NEC in the neonatal period. Methods This is a case-control study, with case-group be...
The overall goal of this retrospective registry study is to investigate the burden-of illness in atrial fibrillation (AF) in Denmark. Several Danish registries will be utilized to collect ...
In Denmark, every 4 birth induced, most often due to prolonged pregnancy, up til 10-12 days after term. A group (RADS) set up by the Danish Regions has recently recommended induction with ...
PBN MEDICALS Denmark A/S is a company in the international InterV group, owned by Canadian Angiotech Pharmaceuticals Inc., Vancouver. InterV is the combined name for the PBN MEDICALS (Denmark) and MD ...
Venture Cup Denmark is a yearly held professional business plan competition. Teams must have at least one person related to a university or business school in Denmark [as a student at bachelor level,...
TopoTarget and CuraGen Announce Initiation of NCI-sponsored Phase II Clinical Trial with PXD101 for MesotheliomaTopoTarget A/S and CuraGen Corporation announced today the initiation of patient dosing ...
The Science Park Association in Denmark is an organization of science parks and innovative incubators in Denmark. The Association is a nationwide forum for exchange of experience and opinion formation...
We have published hundreds of BioTechNews Denmark news stories on BioPortfolio along with dozens of BioTechNews Denmark Clinical Trials and PubMed Articles about BioTechNews Denmark for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of BioTechNews Denmark Companies in our database. You can also find out about relevant BioTechNews Denmark Drugs and Medications on this site too.
In a clinical trial or interventional study, participants receive specific interventions according to the research plan or protocol created by the investigators. These interventions may be medical products, such as drugs or devices; procedures; or change...
Cancer is not just one disease but many diseases. There are more than 100 different types of cancer. Most cancers are named for the organ or type of cell in which they start - for example, cancer that begins in the colon is called colon cancer; cancer th...