Synergy Pharmaceuticals, Inc. Company Profile

11:28 EDT 19th September 2017 | BioPortfolio

Synergy is a biopharmaceutical company focused on the development of new drugs to treat gastrointestinal disorders and diseases. Synergy's proprietary drug SP-304 is a synthetic analog of the human gastrointestinal hormone uroguanylin, and acts by activating the guanylate cyclase C (GC-C) receptor on epithelial cells of the GI tract. SP-304 has completed a Phase I clinical trial in volunteers and is presently in a Phase 2a clinical trial of SP-304 in patients to treat chronic constipation. The Company expects to obtain topline data from this trial in 2010, and use those data to begin a Phase 2b 28-day repeated-oral-dose, placebo-controlled trial in SP-304 in CC patients in early 2011 and a Phase 2b 90-day repeated-oral-dose, placebo-controlled trial of SP-304 in IBS-C patients in the second quarter of 2011. More information is available at

News Articles [1333 Associated News Articles listed on BioPortfolio]

Synergy Pharmaceuticals to Present at the Jefferies 2017 Global Healthcare Conference

Synergy Pharmaceuticals Inc. (NASDAQ:SGYP) today announced that the company will present a corporate update at the Jefferies Global Healthcare Conference in New York City on Thurs...

Expanded use of Synergy's Trulance accepted for FDA review

Synergy Pharmaceuticals' supplemental new drug application for Trulance, or plecanatide, for irritable bowel syndrome with co -More- 

Synergy Pharmaceuticals to Present at Upcoming September Investor Conferences

Synergy Pharmaceuticals Inc. (NASDAQ: SGYP) today announced that the company will present corporate updates at three upcoming investor conferences in New York City during Septembe...

FDA accepts Synergy’s sNDA for Trulance to treat adults with IBS-C

The US Food and Drug Administration (FDA) has accepted Synergy Pharmaceuticals’ supplemental New Drug Application (sNDA) Trulance (plecanatide) for the treatment of adults with irritable bowel syndr...

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PubMed Articles [267 Associated PubMed Articles listed on BioPortfolio]

Exo-exo synergy between Cel6A and Cel7A from Hypocrea jecorina: role of carbohydrate binding module and the endo-lytic character of the enzymes.

Synergy between cellulolytic enzymes is essential in both natural and industrial breakdown of biomass. In addition to synergy between endo-lytic and exo-lytic enzymes, a lesser known but equally consp...

Flexion synergy overshadows flexor spasticity during reaching in chronic moderate to severe hemiparetic stroke.

Pharmaceutical intervention targets arm flexor spasticity with an often-unsuccessful goal of improving function. Flexion synergy is a related motor impairment that may be inadvertently neglected. Here...

The fibronectin synergy site re-enforces cell adhesion and mediates a crosstalk between integrin classes.

Fibronectin (FN), a major extracellular matrix component, enables integrin-mediated cell adhesion via binding of α5β1, αIIbβ3 and αv-class integrins to an RGD-motif. An additional linkage for α5...

Announcing the 2017 Pharmaceuticals Travel Award for Young Post-Doctoral Researchers.

Last year, for the first time in its history, our Journal was able to offer a travel grant of 800 CHF to a young researcher in the field of medicinal chemistry.

Suspended solids moderate the degradation and sorption of waste water-derived pharmaceuticals in estuarine waters.

This study focuses on the fate of pharmaceuticals discharged into an estuarine environment, particularly into the Turbidity Maximum Zone (TMZ). Batch experiments were set up to investigate the factors...

Clinical Trials [259 Associated Clinical Trials listed on BioPortfolio]

A 2x2 Factorial Randomized Controlled Trial of Colchicine and Spironolactone in Patients With STEMI Who Have Undergone PCI With SYNERGY Stent Registry

The CLEAR SYNERGY trial will study the long term effects of three multidisciplinary treatments following PCI to treat ST elevation myocardial infarction. These treatments address both the ...

IRIS-Synergy Cohort in the IRIS-DES Registry

The purpose of this study is to evaluate the relative effectiveness and safety of Synergy stent compared to other drug eluting stents.

Safety and Performance Evaluation of CircuLite Synergy

The purpose of the study is to demonstrate the safety and functionality of the CircuLite Synergy Pocket Circulatory Assist Device.

Registry Experience at the Washington Hospital Center With Drug Eluting Stents - Synergy

To compare the incidence of major adverse cardiac events among a series of patients receiving the Synergy drug-eluting stent with bioabsorbable polymer to historical controls who have rece...

SYNERGY China: Assess SYNERGY Stent in China

Prospective, multicenter, single-arm study, enroll 100 patients in no more than 10 sites across China, the primary endpoint is Technical success.

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Synergy Pharmaceuticals, Inc.

Synergy is a biopharmaceutical company focused on the development of new drugs to treat gastrointestinal disorders and diseases. Synergy's proprietary drug SP-304 is a synthetic a...

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More Information about "Synergy Pharmaceuticals, Inc." on BioPortfolio

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