Magainin Pharmaceuticals Inc. Company Profile

News Articles [ 1 Associated News Articles listed on BioPortfolio]

AltheRx Pharmaceuticals Appoints Michael R Dougherty to Board of Directors

AltheRx Pharmaceuticals, a privately-held clinical development company, today announced the appointment of Michael R Dougherty, former President and CEO of Adolor Corporati...

Drugs and Medications [0 Results]

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PubMed Articles [ 16 Associated PubMed Articles listed on BioPortfolio]

Inducing toxicity by introducing a leucine zipper like motif in frog antimicrobial peptide, magainin 2.

Cytotoxicity, a major obstacle in therapeutic application of antimicrobial peptides, is controlled by leucine zipper like sequences in melittin and other naturally-occurring antimicrobial peptides. Ma...

Kinetic pathway of antimicrobial peptide magainin 2-induced pore formation in lipid membranes.

The pore formation in lipid membranes induced by the antimicrobial peptide magainin 2 is considered to be the main cause for its bactericidal activity. To reveal the mechanism of the pore formation, i...

Lipid-Controlled Peptide Topology and Interactions in Bilayers: Structural Insights into the Synergistic Enhancement of the Antimicrobial Activities of PGLa and Magainin 2.

To gain further insight into the antimicrobial activities of cationic linear peptides, we investigated the topology of each of two peptides, PGLa and magainin 2, in oriented phospholipid bilayers in t...

Difference between Magainin-2 and Melittin Assemblies in Phosphatidylcholine Bilayers: Results from Coarse-Grained Simulations.

We performed coarse-grained computer simulations using MARTINI force field to study the difference in the self-assembly and possible pore creation in DPPC phospholipid membranes by two different antim...

Enhancement of cytotoxicity of antimicrobial peptide magainin II in tumor cells by bombesin-targeted delivery.

Aim:To investigate whether the conjugation of magainin II (MG2), an antimicrobial peptides (AMPs), to the tumor-homing peptide bombesin could enhance its cytotoxicity in tumor cells.Methods:A magainin...

Clinical Trials [ 1 Associated Clinical Trials listed on BioPortfolio]

MSI-78 Topical Cream vs. Oral Ofloxacin in the Treatment of Infected Diabetic Ulcers

224 adults with diabetic foot ulcers will be randomized to either magainin peptide (MSI-78) or ofloxacin (FLOXIN, Ortho-McNeil Pharmaceutical Corporation) an oral fluoroquinolone antibioti...

Companies [ 2 Associated Companies listed on BioPortfolio]

Magainin Pharmaceuticals Inc.

Magainin Pharmaceuticals Inc. is a biopharmaceutical company committed to developing medicines for serious diseases from genomics and natural products. Research and development efforts in anti-angiog...

Genaera

Genaera Corporation is a biopharmaceutical company committed to developing medicines for serious diseases from genomics and natural products. Our research and development efforts are focused on anti-a...