Advertisement

Topics

Protox Therapeutics Inc. Company Profile

18:16 EDT 27th June 2016 | BioPortfolio

Protox Therapeutics is a product-focused development-stage company and a leader in advancing novel, targeted protein toxin therapeutics for the treatment of cancer and other proliferative diseases. Through the company’s INxin™ and PORxin™ technology platforms, therapeutic candidates are generated by engineering the naturally occurring toxins, Pseudomonas exotoxin and proaerolysin. These drugs are potent anti-cancer agents with distinct modes of action.INxin™ drugs target cancer cells that produce specific tumor associated receptors on their cell surface. Once bound to the cancer cells, INxin™ drugs enter the cell and inhibit protein synthesis which ultimately leads to cell death. A Phase II clinical trial has been completed with Protox’s lead compound, PRX321, for the treatment of primary brain cancer, specifically recurrent malignant glioblastoma multiforme and astrocytoma. A Phase I clinical trial has also been completed for both renal cell carcinoma and non-small cell lung cancer. PRX321 is also in pre-clinical development for other peripheral solid tumors and hematological tumors

Location

1210-885 West Georgia Street
Vancouver
British Columbia
V6C 3E8
Canada

Contact

Email: info@protoxtherapeutics.com


News Articles [1227 Associated News Articles listed on BioPortfolio]

BIND Therapeutics collaborates with Affilogic

BIND Therapeutics, a company developing targeted and programmable therapeutics called ACCURINS, has signed…

Placon Therapeutics launches, BTP-114 IND accepted by FDA

Placon Therapeutics, a biotechnology company developing next-generation platinum-based cancer therapies, has launched as an independent company and provided an update on its lead product candidate, BT...

Bicycle Therapeutics establishes U.S. operations

Bicycle Therapeutics, a biotechnology company pioneering a new class of therapeutics based on its proprietary bicyclic peptides (Bicycles) platform, has established U.S. operations with headquarters i...

Living Therapeutics

An MIT spinout, Synlogic, is aiming to create a new class of medicines, by re-programming bacteria found in the gut as “living therapeutics.”Read more about Living Therapeutics Comments

Tarveda spins platinum-based drug assets out into newco Placon Therapeutics

Tarveda Therapeutics Inc. (formerly Blend Therapeutics) spun out its development-stage platinum-based cancer assets into a new independent entity named Placon Therapeutics.

Wilson Therapeutics AB: Change in Number of Shares in Wilson Therapeutics

Regulatory News: Wilson Therapeutics (STO:WTX) The number of shares and votes in Wilson Therapeutics AB (publ) has changed as a result of the new issue of shares that was made in connection with t...

Intensity Therapeutics Inc.

Intensity Therapeutics Inc.'s DfuseRx platform combines known, potent chemotherapeutics with cell-penetration enhancing compounds. The resulting therapeutics are designed to kill tumor cells in masse...

AstraZeneca to collaborate with Moderna Therapeutics to develop mRNA therapeutics

Anglo-Swedish pharma company AstraZeneca will join forces with US biotech firm Moderna Therapeutics to…

Drugs and Medications [0 Results]

None

PubMed Articles [497 Associated PubMed Articles listed on BioPortfolio]

Injectable biomaterials: a perspective on the next wave of injectable therapeutics.

We are experiencing a new wave of injectable therapeutics (namely/injectable biomaterials) to complement injectable drugs and injectable biologics, and to serve as the basis for injectable combinatori...

Pigmentation and Macular Degeneration: Is There a Role for GPR143?

Fit for the Eye: Aptamers in Ocular Disorders.

For any new class of therapeutics, there are certain types of indications that represent a natural fit. For nucleic acid ligands in general, and aptamers in particular, the eye has historically been a...

Eyes on New Product Development.

Reviewer Acknowledgment 2015.

Clinical Trials [3 Associated Clinical Trials listed on BioPortfolio]

Localized Therapeutics for the Treatment of Gastrointestinal Disorders II

The purpose of this study is to investigate a novel thermosensitive topical gel formulation for the treatment of inflammatory bowel disease (IBD), specifically ulcerative colitis.

Heart Rate Variability Biofeedback: It's Role in Asthma Therapeutics

The goal of this research study to see whether biofeedback therapy helps treat asthma, and if so, how it works. Biofeedback is a treatment method that can teach people how to control their...

Pharmaceutical Collaborative Care Integrated to a Multidisciplinary Psychosocial Program

Caring for patients with Alzheimer Disease or Related Disorders (ADRD) is accompanied with a caregiver burden that increases with the progression of the disease. This burden can have physi...

Companies [1 Associated Companies listed on BioPortfolio]

Protox Therapeutics Inc.

Protox Therapeutics is a product-focused development-stage company and a leader in advancing novel, targeted protein toxin therapeutics for the treatment of cancer and other proliferative diseases. Th...

More Information about "Protox Therapeutics Inc." on BioPortfolio

We have published hundreds of Protox Therapeutics Inc. news stories on BioPortfolio along with dozens of Protox Therapeutics Inc. Clinical Trials and PubMed Articles about Protox Therapeutics Inc. for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Protox Therapeutics Inc. Companies in our database. You can also find out about relevant Protox Therapeutics Inc. Drugs and Medications on this site too.

Quick Search
Advertisement
 

Relevant Topics

Nutrition
Within medicine, nutrition (the study of food and the effect of its components on the body) has many different roles. Appropriate nutrition can help prevent certain diseases, or treat others. In critically ill patients, artificial feeding by tubes need t...

Head and neck cancers
Cancer can occur in any of the tissues or organs in the head and neck. There are over 30 different places that cancer can develop in the head and neck area. Mouth cancers (oral cancers)  - Mouth cancer can develop on the lip, the tongue, the floor...

Cancer Disease
Cancer is not just one disease but many diseases. There are more than 100 different types of cancer. Most cancers are named for the organ or type of cell in which they start - for example, cancer that begins in the colon is called colon cancer; cancer th...


Corporate Database Quicklinks



Searches Linking to this Company Record