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Protox Therapeutics Inc. Company Profile

15:20 EST 4th December 2016 | BioPortfolio

Protox Therapeutics is a product-focused development-stage company and a leader in advancing novel, targeted protein toxin therapeutics for the treatment of cancer and other proliferative diseases. Through the company’s INxin™ and PORxin™ technology platforms, therapeutic candidates are generated by engineering the naturally occurring toxins, Pseudomonas exotoxin and proaerolysin. These drugs are potent anti-cancer agents with distinct modes of action.INxin™ drugs target cancer cells that produce specific tumor associated receptors on their cell surface. Once bound to the cancer cells, INxin™ drugs enter the cell and inhibit protein synthesis which ultimately leads to cell death. A Phase II clinical trial has been completed with Protox’s lead compound, PRX321, for the treatment of primary brain cancer, specifically recurrent malignant glioblastoma multiforme and astrocytoma. A Phase I clinical trial has also been completed for both renal cell carcinoma and non-small cell lung cancer. PRX321 is also in pre-clinical development for other peripheral solid tumors and hematological tumors

Location

1210-885 West Georgia Street
Vancouver
British Columbia
V6C 3E8
Canada

Contact

Email: info@protoxtherapeutics.com


News Articles [1884 Associated News Articles listed on BioPortfolio]

PX'Therapeutics und RELIEF THERAPEUTICS Holding AG kündigen strategischen Kooperationsvertrag für rekombinante Produktion von Atexakin Alfa an

PX'Therapeutics, Tochtergesellschaft des Aguettant Konzerns, ein Unternehmen, das sich auf die kundenspezifische Entwicklung rekombinanter Proteine konzentriert, und die RELIEF THERAPEUTICS Holdin...

Domain Therapeutics sets up Mavalon Therapeutics, with financial backing from Medicxi

French drug discovery company Domain Therapeutics today announced the creation of Mavalon Therapeutics,…

Research Reports Coverage on Biotech Stocks -- Celldex Therapeutics, Amicus Therapeutics, ...

http://stock-callers.com/registration Celldex Therapeutics  On Thursday, shares in Hampton, New Jerseyheadquartered Celldex Therapeutics Inc. recorded a trading volume of 3.36 million shares, whi...

Seres Therapeutics, Emulate collaborate to support development of novel microbiome therapeutics

Seres Therapeutics, a microbiome therapeutics platform company, and Emulate, a private firm commercializing the Organs-on-Chips technology, announced a new collaboration.

Relief Therapeutics kündigt strategische Allianz mit PX'Therapeutics an

Genf/Grenoble (awp) - Das Biotechunternehmen Relief Therapeutics kündigt eine strategische Zusammenarbeit mit PX'Therapeutics an. Gemeinsam werden die beiden Unternehmen an der Produktion von Atexa.....

Antegrin and Cascadia merge to form Indalo Therapeutics

Antegrin Therapeutics and Cascadia Therapeutics have established Indalo Therapeutics, a biotechnology company dedicated to developing novel therapies to treat fibrotic diseases.

Magenta Therapeutics Announces $48.5M Financing

NewsMagenta Therapeutics aspires to develop a patient-focused set of therapeutics with the first complete platform that addresses the critical challenges in stem cell transplant.

PX'Therapeutics and RELIEF THERAPEUTICS Holding AG Announce a Strategic Collaboration Agreement for the Recombinant Production of Atexakin Alfa

PX'Therapeutics, a subsidiary of the Aguettant group, a company that specializes in the customer-tailored development of recombinant proteins, and RELIEF THERAPEUTICS Holding AG ("Relief", SIX : R...

Drugs and Medications [0 Results]

None

PubMed Articles [492 Associated PubMed Articles listed on BioPortfolio]

Injectable biomaterials: a perspective on the next wave of injectable therapeutics.

We are experiencing a new wave of injectable therapeutics (namely/injectable biomaterials) to complement injectable drugs and injectable biologics, and to serve as the basis for injectable combinatori...

Response #2 to Immediate Intraocular Pressure Tendency Following Intravitreal Delivery of Dexamethasone Implant; Alagöz et al. J. Ocul. Pharmacol. Ther. 32:44-49, 2016.

Comparison of Self-Reported and Objective Adherence to Antiglaucoma Medications.

Pigmentation and Macular Degeneration: Is There a Role for GPR143?

Fit for the Eye: Aptamers in Ocular Disorders.

For any new class of therapeutics, there are certain types of indications that represent a natural fit. For nucleic acid ligands in general, and aptamers in particular, the eye has historically been a...

Clinical Trials [12 Associated Clinical Trials listed on BioPortfolio]

Beat AML Core Study

In this study, DNA sequencing, computational biology modeling, and ex vivo drug sensitivity assays will be utilized to define clinically relevant gene mutations and identify potential ther...

Localized Therapeutics for the Treatment of Gastrointestinal Disorders II

The purpose of this study is to investigate a novel thermosensitive topical gel formulation for the treatment of inflammatory bowel disease (IBD), specifically ulcerative colitis.

Impact of a Monitoring Device for Patients With Cancer Treated Using Oral Therapeutics

The emergence of oral delivery in cancer therapeutics is expected to result in an increased need for better coordination between all treatment stakeholders, mainly to ensure adequate treat...

Heart Rate Variability Biofeedback: It's Role in Asthma Therapeutics

The goal of this research study to see whether biofeedback therapy helps treat asthma, and if so, how it works. Biofeedback is a treatment method that can teach people how to control their...

Interest of Pain Assessment by the Family of Patients in Limiting and Stopping Active Treatment Process Admitted in ER. Study DOFAMILA

Decisions to limit and stop active therapeutics are common in the emergency unit. They are framed by the Leonetti law of 22 April 2005 recommending the refusal of unreasonable obstinacy an...

Companies [1 Associated Companies listed on BioPortfolio]

Protox Therapeutics Inc.

Protox Therapeutics is a product-focused development-stage company and a leader in advancing novel, targeted protein toxin therapeutics for the treatment of cancer and other proliferative diseases. Th...

More Information about "Protox Therapeutics Inc." on BioPortfolio

We have published hundreds of Protox Therapeutics Inc. news stories on BioPortfolio along with dozens of Protox Therapeutics Inc. Clinical Trials and PubMed Articles about Protox Therapeutics Inc. for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Protox Therapeutics Inc. Companies in our database. You can also find out about relevant Protox Therapeutics Inc. Drugs and Medications on this site too.

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