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Protox Therapeutics Inc. Company Profile

15:27 EST 18th January 2017 | BioPortfolio

Protox Therapeutics is a product-focused development-stage company and a leader in advancing novel, targeted protein toxin therapeutics for the treatment of cancer and other proliferative diseases. Through the company’s INxin™ and PORxin™ technology platforms, therapeutic candidates are generated by engineering the naturally occurring toxins, Pseudomonas exotoxin and proaerolysin. These drugs are potent anti-cancer agents with distinct modes of action.INxin™ drugs target cancer cells that produce specific tumor associated receptors on their cell surface. Once bound to the cancer cells, INxin™ drugs enter the cell and inhibit protein synthesis which ultimately leads to cell death. A Phase II clinical trial has been completed with Protox’s lead compound, PRX321, for the treatment of primary brain cancer, specifically recurrent malignant glioblastoma multiforme and astrocytoma. A Phase I clinical trial has also been completed for both renal cell carcinoma and non-small cell lung cancer. PRX321 is also in pre-clinical development for other peripheral solid tumors and hematological tumors

Location

1210-885 West Georgia Street
Vancouver
British Columbia
V6C 3E8
Canada

Contact

Email: info@protoxtherapeutics.com


News Articles [1853 Associated News Articles listed on BioPortfolio]

PX'Therapeutics und RELIEF THERAPEUTICS Holding AG kündigen strategischen Kooperationsvertrag für rekombinante Produktion von Atexakin Alfa an

PX'Therapeutics, Tochtergesellschaft des Aguettant Konzerns, ein Unternehmen, das sich auf die kundenspezifische Entwicklung rekombinanter Proteine konzentriert, und die RELIEF THERAPEUTICS Holdin...

Domain Therapeutics sets up Mavalon Therapeutics, with financial backing from Medicxi

French drug discovery company Domain Therapeutics today announced the creation of Mavalon Therapeutics,…

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http://stock-callers.com/registration Celldex Therapeutics  On Thursday, shares in Hampton, New Jerseyheadquartered Celldex Therapeutics Inc. recorded a trading volume of 3.36 million shares, whi...

Relief Therapeutics kündigt strategische Allianz mit PX'Therapeutics an

Genf/Grenoble (awp) - Das Biotechunternehmen Relief Therapeutics kündigt eine strategische Zusammenarbeit mit PX'Therapeutics an. Gemeinsam werden die beiden Unternehmen an der Produktion von Atexa.....

Antegrin and Cascadia merge to form Indalo Therapeutics

Antegrin Therapeutics and Cascadia Therapeutics have established Indalo Therapeutics, a biotechnology company dedicated to developing novel therapies to treat fibrotic diseases.

Bicycle Therapeutics signs cancer development deal with CRUK

Cancer Research UK and its commercialisation arm are to work with UK biotech firm Bicycle Therapeutics on a novel approach to targeting cancer. Bicycle Therapeutics has developed a new class of thera...

Magenta Therapeutics Announces $48.5M Financing

NewsMagenta Therapeutics aspires to develop a patient-focused set of therapeutics with the first complete platform that addresses the critical challenges in stem cell transplant.

PX'Therapeutics and RELIEF THERAPEUTICS Holding AG Announce a Strategic Collaboration Agreement for the Recombinant Production of Atexakin Alfa

PX'Therapeutics, a subsidiary of the Aguettant group, a company that specializes in the customer-tailored development of recombinant proteins, and RELIEF THERAPEUTICS Holding AG ("Relief", SIX : R...

Drugs and Medications [0 Results]

None

Clinical Trials [18 Associated Clinical Trials listed on BioPortfolio]

A Trial to Find Safe and Active Doses of an Investigational Drug CX-072 for Patients With Solid Tumors or Lymphomas

The purpose of this first-in-human study of CX-072 is to characterize the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and antitumor activity of CX-072 administered i...

Beat AML Core Study

In this study, DNA sequencing, computational biology modeling, and ex vivo drug sensitivity assays will be utilized to define clinically relevant gene mutations and identify potential ther...

Localized Therapeutics for the Treatment of Gastrointestinal Disorders II

The purpose of this study is to investigate a novel thermosensitive topical gel formulation for the treatment of inflammatory bowel disease (IBD), specifically ulcerative colitis.

Amnis Therapeutics Thrombectomy Device-First in Man (FIM) Safety and Performance Study

Prospective, single-arm, open label, Safety and Performance clinical investigation.

A Gene Transfer Study for Hemophilia A

This clinical research study is being conducted by Spark Therapeutics, Inc. to determine the safety and efficacy of the factor VIII gene transfer treatment with SPK-8011 in individuals wit...

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Protox Therapeutics Inc.

Protox Therapeutics is a product-focused development-stage company and a leader in advancing novel, targeted protein toxin therapeutics for the treatment of cancer and other proliferative diseases. Th...

Constance Therapeutics

Constance Therapeutics is a vertically integrated medicinal cannabis company producing standardized and science-based whole plant cannabis extracts. The company has created a new ...

venBio Select Advisor LLC

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More Information about "Protox Therapeutics Inc." on BioPortfolio

We have published hundreds of Protox Therapeutics Inc. news stories on BioPortfolio along with dozens of Protox Therapeutics Inc. Clinical Trials and PubMed Articles about Protox Therapeutics Inc. for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Protox Therapeutics Inc. Companies in our database. You can also find out about relevant Protox Therapeutics Inc. Drugs and Medications on this site too.

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