Therapeutic Proteins Ltd., Company Profile

News Articles [ 517 Associated News Articles listed on BioPortfolio]

Bartholomew’s BioNotes: The carrot juice IS your medicine

Many important drugs are composed of proteins, e.g. insulin, clotting factors, growth hormone, etc. While is physically possible to fashion these proteins into pills, the proteins are destroyed when t...

Selective enrichment of newly synthesized proteins for quantitative secretome analysis

Measuring secreted proteins in cell culture is difficult because of high amounts of background proteins in serum-containing media. By combining two metabolic labeling techniques, Eichelbaum et al. det...

How to make disease-causing proteins vulnerable to drugs

One of the most daunting challenges facing pharmaceutical scientists today are “undruggable proteins” – the approximately 80% of proteins involved in human disease that do not interact with curr...

Scientists succeed in solving first structure of a Wnt protein

The 20 proteins in the Wnt family are some of the most important proteins in controlling how an organism develops and grows, but for 30 years scientists have not known what these vital proteins actual...

Reagent Proteins Unveils E-Commerce Site

San Diego-based Pfenex, which uses a fluorescing proteobacteria to make specialized protein-based products, says its Reagent Proteins division has launched a new e-commerce site that offers more than...

PPR proteins recognise RNA targets via easy-to-understand code

The code determines the recognition of RNA molecules by a superfamily of RNA-binding proteins called pentatricopeptide repeat (PPR) proteins.

Describing For The First Time How PPR Proteins Recognise Their RNA Targets

Scientists have cracked a molecular code that may open the way to destroying or correcting defective gene products, such as those that cause genetic disorders in humans. The code determines the recogn...

Blocking destruction of defective proteins unexpectedly delays neurodegeneration in mice

One might expect that ridding a brain cell of damaged proteins would be a universally good thing, and that impairing the cell's ability to do this would allow the faulty proteins to accumulate within...

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PubMed Articles [ 71 Associated PubMed Articles listed on BioPortfolio]

Plant phosphopeptide-binding proteins as signaling mediators.

Regulation of the activity, location, and interactions of proteins by phosphorylation is crucial for many cellular processes including regulation of signaling. Phosphorylation-dependent interactions b...

Armadillo-repeat protein functions: questions for little creatures.

Armadillo (ARM)-repeat proteins form a large family with diverse and fundamental functions in many eukaryotes. ARM-repeat proteins have largely been characterised in multicellular organisms and much i...

Denatured bactericidal proteins: Active per se, or reservoirs of active peptides?

According to the structure-to-function paradigm proteins fold into a 3D structure for exerting their functions. Intrinsically destructured proteins with important biological functions have been identi...

Characterization of the subcellular localization of herpes simplex virus type 1 proteins in living cells.

In this study, we presented the construction of a library of expression clones for the herpes simplex virus type 1 (HSV-1) proteome and subcellular localization map of HSV-1 proteins in living cells u...

Viral security proteins: counteracting host defences.

Interactions with host defences are key aspects of viral infection. Various viral proteins perform counter-defensive functions, but a distinct class, called security proteins, is dedicated specificall...

Clinical Trials [ 433 Associated Clinical Trials listed on BioPortfolio]

Prolonged Fasting and FGF-21 Levels

This study will look at the effect of 72 hours of fasting (not eating) on levels of proteins that are involved in metabolism. These proteins will be measured in blood and fat tissue. The i...

Analysis of Human Tear Proteins

The significance of our study is in the importance of understanding the quality and quantity of proteins in the human tear film from diseased and non-diseased patients. This pilot study w...

Circulating Markers That Underlie the Transition From Compensated Hypertrophy to Heart Failure

The purpose of this research is to determine if two proteins in the blood are increased during acute heart failure. These two proteins are produced when the heart becomes dysfunctional an...

The Effect of Aspirin on Angiogenesis Proteins in Women on Tamoxifen Therapy

Changes in major angiogenic proteins have been seen following initiation of tamoxifen and aromatase inhibitor therapy in women with breast cancer. One source of these proteins is the circu...

An Open Label, Canadian Phase IIIb Study With Ovidrel in Ovulation Induction (OI) and Assisted Reproductive Technique (ART)

With the development of the recombinant gonadotrophins, the use of human source proteins for the production of hormones has become unnecessary. These proteins, which are found in urinary p...

Companies [ 495 Associated Companies listed on BioPortfolio]

Therapeutic Proteins Ltd.,

Therapeutic Proteins Ltd., is a world class global developer and supplier of biosimilar recombinant therapeutic proteins. Manufactured in fully cGMP compliant facilities in Europe and North America, o...

NewEast Biosciences

NewEast Biosciences are specialized in generating protein configuration-specific monoclonal antibodies that recognize active (GTP-bound) G proteins (including Ras-superfamily small GTPases and hete...

AvidBiotics Corp.

AvidBiotics is developing two proprietary platforms for the generation of non-antibody proteins against infectious diseases and cancers: Avidocin™ proteins and Micacide™...

BIOPUR AG

BIOPUR manufactures highly purified proteins and enzymes derived from human and animal sources for research use. Our focus is the extraction of proteins and enzymes from native plasma and other source...

Scil Proteins

Scil Proteins is a biopharmaceutical company working with industry partners in the development and manufacture of protein therapeutics and diagnostics as well as discovering and d...