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The business objective of Axiogenesis lies in the area of clinical (red) biotechnology, specifically in the production of stem cell-based assays that enable drug development. These innovative and proprietary assays accelerate and improve drug candidate selection, lower costs and thus increase overall drug development efficiency. At present the main focus is heart muscle disease (cardiomyopathy).
Since early 2008, the first products of Axiogenesis have been actively marketed and are already generating significant turnovers.
This range of products has been further developed during the last months employing groundbreaking human induced Pluripotent Stem cell (iPS) technology. Through in-house development of human iPS technology, the next product generation of murine embryonic stem cells will be complemented with human stem cell-derived tissues.
With this technology it is possible to reverse-differentiate (or de-differentiate) adult human cells (e.g., skin or blood cells) to an artificial embryonic state. Using proprietary technology, Axiogenesis then forward-differentiates these into pure organ specific cells and defined tissues. Proof of concept of this two-step method was established in-house during November 2008. The first human, organ-specific iPS cells will be available for sale by the end of 2011.
A range of tissue models (including heart, liver and nerve) will be produced through the proliferation and differentiation of genetically modified stem cells. These are used to test efficacy and potential adverse side effects of drug candidates.
Increased drug development efficiency, with the use of Axiogenesis technology, is achieved through:
Furthermore the system lends itself to product line extension through rapid testing of side effect profiles and improvements in efficacy of modified compounds or through the identification of novel indications of existing active pharmaceutical ingredients (APIs).
Grundlage gebildet, um der führende Anbieter für hiPSC-basierte Drug Discovery- Lösungen zu werden Axiogenesis und Pluriomics fusionieren zu Ncardia (www.ncardia.com). Das Privatunternehmen, das i....
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Builds foundation to become the trusted leader in hiPSC based drug discovery solutions Ncardia (www.ncardia.com) has been established following the merger of Pluriomics...
SummaryAxiogenesis AG Axiogenesis is a preclinical biotechnology company that specializes in development and production of stem cellderived cell types. The company offers products such as cardiac cell...
The business objective of Axiogenesis lies in the area of clinical (red) biotechnology, specifically in the production of stem cell-based assays that enable drug development. These innovative and pr...
We have published hundreds of Axiogenesis AG news stories on BioPortfolio along with dozens of Axiogenesis AG Clinical Trials and PubMed Articles about Axiogenesis AG for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Axiogenesis AG Companies in our database. You can also find out about relevant Axiogenesis AG Drugs and Medications on this site too.
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