MRM Proteomics Inc. Company Profile
MRM Proteomics is a leading provider of advanced protein quantification, biomarker and proteomic services to the pharmaceutical, biotechnology and diagnostics industries. We are specialists in quantitative targeted proteomics through the use and development of Multiple Reaction Monitoring-Mass Spectrometry (MRM-MS).
Our MRM-MS platform technology has a wide number of applications in drug discovery and clinical development particularly with regards to biomarker discovery/validation, drug toxicity and cell signalling research.
Our approach allows for the rapid and efficient development of life science research projects and drug development programs. It is rapid and inexpensive compared with ELISA development. Our assays can be highly multiplexed to allow for the quantification and analysis of 10s to 100s of proteins/biomarkers in one analysis from a single drop of blood serum or plasma as well as other fluids/tissues.
Our PeptiQuant™ MRM Assays (Pre-defined and/or Custom designed) have several significant advantages over other protein/biomarker quantification methods, including HPLC and antibody based ELISA assays.
- Short assay development time – 10 to 16 weeks.
- No antibody development costs
- Highly multiplexed assays (10s to 100s of proteins/biomarkers)
- Absolute protein quantification
- Absolute molecular specificity
- Same analysis can be applied in preclinical & clinical testing
- Ability to quantify isoforms and post-trans modifications
- Minimal sample volumes (10-20ul)
Choose from our established PeptiQuant™ Panels:
- Human Plasma Discovery MRM Assay
- Human Cardiovascular MRM Assay
- Mouse Discovery MRM Assay
- PeptiQuant™ Custom MRM Assay service.
MRM Proteomics’ Custom MRM assay service provides our customers with the ultimate flexibility in designing their own customized MRM assays. You can design your own made-to-measure assay using any combination of the proteins listed in our standard menu.
PeptiQuant™ MRM Assays are extremely versatile and can be used in a large number of protein quantification and biomarker applications.
- Biomarker discovery, verification and validation
- Stratification of patients
- Probing cell signalling pathways
- Development of companion diagnostics
- Drug Toxicity assessments in serum samples
- Pharmacokinetic (pK) studies
- Quality control studies of biologics
For more information, please visit: www.mrmproteomics.com .
Location
311-1275 WEST 6TH AVE
Vancouver
British Columbia
V6H 1A6
Canada
Contact
Phone: +1 (604) 800-2296
Fax: +1 (604) 800-2297
Email: info@mrmproteomics.com
News Articles
Metabolic fingerprinting: Using proteomics to identify proteins in gymnosperm pollination drops
(American Journal of Botany) Proteomics is a powerful technique for examining the structure and function of the proteome. Proteomics can uncover the relationship between DNA, RNA, and the production o...
Unlabeled proteomics: Sidebar: Activiomics Ltd. Corporate Profile
Activiomics: Unlabeled proteomics Activiomics Ltd. London, U.K. Technology: TIQUAS label-free proteomics technology Disease focus: Cancer, inflammation, metabolic Clinical status: Discovery Founded: 2...
BC Proteomics Network receives renewed funding from MSFHR
The BC Proteomics Network has received renewed funding from the Michael Smith Foundation for Health Research (MSFHR) totaling $1.6 million over a five year term. The second phase of MSFHR funding will...
Tecan microarray solutions transform functional proteomics workflows at ASU
“We have adopted a unique approach to functional proteomics..."
Potential Blood Biomarkers for Stroke
Technological advances in proteomics have permitted a more effective search for novel biomarkers in stroke. What are the latest -- and most promising -- biomarker candidates? Expert Review of Proteo...
Bruker and the University of Victoria-Genome British Columbia Proteomics Centre (UVic GBC Proteomics Centre) have announced a collaborative effort for the development and validati...
Mass spectra for >100,000 synthetic peptides provide a basis for improving proteomics experiments and analysis algorithms.
The new age of proteomics: An integrative vision of the cellular world
(Centro Nacional de Investigaciones Oncologicas (CNIO)) The head of CNIO's Proteomics Core Unit, Javier Muñoz, working alongside Dutch researchers, revises the technology of the post-‐ge...
Drugs and Medications
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PubMed Articles
Two-dimensional gel electrophoresis in proteomics: past, present and future.
Two-dimensional gel electrophoresis has been instrumental in the birth and developments of proteomics, although it is no longer the exclusive separation tool used in the field of proteomics. In this r...
Viewpoints in Clinical Proteomics - when will proteomics deliver clinically useful information?
Proteomics has not delivered biomarkers of clinical value, despite massive efforts. The technologies that are emerging today have, however, the power to reach deep into proteomes and to identify patte...
Pediatric proteomics: an introduction.
The overall goal of this series is to detail the paradigm shift that proteomics will bring to the practice of pediatric medicine and research. Proteomics is the global study of proteins in a biologica...
Translational plant proteomics: A perspective.
Translational proteomics is an emerging sub-discipline of the proteomics field in the biological sciences. Translational plant proteomics aims to integrate knowledge from basic sciences to translate i...
Clinical Trials
Pilot Study of Protein Profiling of the Human Epidermal Cells After Ultraviolet Irradiation
The main focus of this pilot study is to construct a fairly complete protein profile of the epidermis. This will allow us to study how the epidermis responds to external stressors such as...
Proteomics in Morbid Obesity After Bariatric Surgery
Glycemic control is rapidly restored in patients with insulin resistance after bariatric surgery, in particular after the mal-absorptive one (i.e. Bilio-pancreatic diversion, BPD). To ev...
RATIONALE: Diagnostic procedures, such as MRI, MRSI, and tissue proteomics, may help doctors find and diagnose breast cancer and plan the best treatment. PURPOSE: This clinical trial is s...
Alveolar Macrophage Proteomics in HIV-Associated Emphysema
This study is being done to examine lung function changes in individuals with HIV infection and to understand why individuals with HIV have increased risk of lung damage from cigarette smo...
Salivary Proteins in Disease and Health
This study will examine saliva samples from healthy volunteers and patients with various diseases to learn more about how disease affects the mouth and salivary glands. It will use a metho...
Companies
Cystic Fibrosis Enters the Proteomics Scene
As a continuation to genomic research, proteomics now offers the unique advantage to examine global alterations in the protein expression patterns of CF cells and tissues. The systematic use of proteo...
The BC Proteomics Network (BCPN) is a growing network of researchers and informatics professionals from universities, research institutions and industry throughout British Columbia. Formed in...
Proteome Systems commenced operations in January 1999. The Company was founded by Professor Keith Williams and a core team of internationally recognized scientists from the Macquarie University Centre...
1993 Founded as spin off of MPI and Gene Center by Dr. Georg Arnold (Gene Center), Dr. Josef Kellermann (MPI) and Dr. Friedrich Lottspeich (MPI, President of the DGPF) as company for Protein Analytica...
Proxeon was incorporated in 2002 under the laws of Denmark and has become a leading provider of proteomics technology as was its predecessor, Protana (which was acquired by MDS Proteomics Inc in 2000)...
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