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SAGE Therapeutics Company Profile

00:20 EDT 24th May 2013 | BioPortfolio

SAGE Therapeutics is a central nervous system (CNS) product focused company building a portfolio of new therapies to meet the growing unmet need in a range of CNS disorders, including schizophrenia, depression, pain and traumatic brain injury. SAGE Therapeutics’ proprietary Positive and Negative Allosteric Modulator (PANAM) chemistry platform targets the primary excitatory and inhibitory neurotransmitter systems in the brain and enables the development of allosteric modulators that fine tune and balance neuronal activity that is disrupted in CNS disorders. Specifically, SAGE Therapeutics is focused on non-benzodiazepine and non-glycine approaches to modulating GABA and glutamate receptors, respectively. SAGE Therapeutics’ approach leverages extensive knowledge in chemistry, molecular and in vivo pharmacology, formulation technology, biomarker data and compelling clinical proof of concept established for several of its lead programs - all of which will enable SAGE Therapeutics to accelerate the clinical development of its pipeline and bring important medicines to patients. SAGE Therapeutics is a private company launched in 2011 by a proven team of R&D leaders, renowned CNS experts and Third Rock Ventures. For more information, please visit www.sagerx.com.


News Articles [ 165 Associated News Articles listed on BioPortfolio]

SAGE expands open access publishing portfolio into engineering and medicine

(SAGE Publications) SAGE today announced they are launching a further three broad-spectrum open access journals - SAGE Open Medicine, SAGE Open Medical Case Reports and SAGE Open Engineering.

SAGE's open access medicine and engineering journals: Now open for submissions

(SAGE Publications) SAGE today announced that all three of their latest open access journals are now open for submissions - SAGE Open Medicine, SAGE Open Medical Case Reports and SAGE Open Engineering...

SAGE to launch three open access journals in engineering and medicine

SAGE today announced they are launching a further three broad-spectrum open access journals - SAGE Open Medicine, SAGE Open Medical Case Reports and SAGE Open Engineering.

SAGE and the Urban Affairs Association announce the winner of the UAA-SAGE Activist Scholar Award

(SAGE Publications) SAGE and the Urban Affairs Association (UAA) are pleased to announce that Dr. Kitty Kelly Epstein is the 2013 winner of the UAA-SAGE Marilyn Gittell Activist Scholar Lecture Series...

SAGE to publish the Journal of International Medical Research

(SAGE Publications) SAGE has today announced the purchase of the Journal of International Medical Research from Field House Publishing LLP.

SAGE to publish InnovAiT from January 2013

(SAGE Publications) SAGE and the Royal College of General Practitioners have today announced a new agreement to publish InnovAiT from January 2013.

Sage Bionetworks Absorbs Dream, Plans Open Science ‘Challenges’

Sage Bionetworks is a nonprofit, so it isn’t in the business of doing mergers and acquisitions in the traditional sense. But today it’s completing a merger of sorts that will enable it to expand i...

Sage to fold in DREAM Project initiative

The not-for-profit Sage Bionetworks (Seattle, Wash.) said the DREAM Project will be folded into Sage and that Sage and the project will run open science computational challenges together. The DREAM --...

PubMed Articles [ 38 Associated PubMed Articles listed on BioPortfolio]

The effect of harvest periods on the chemical compositions of essential oils of sage (Salvia aucheri L.) leaves.

The essential oils of sage leaves (Salvia aucheri Bentham var. canescens Boiss. & Heldr.), growing wild in South Anatolia, were extracted by hydrodistillation and analysed by GC and GC-MS. The percent...

Rapid UHPLC determination of polyphenols in aqueous infusions of Salvia officinalis L. (sage tea).

Sage tea, the aqueous infusion of dried sage leaves (Salvia officinalis L.), is used as a form of food as well as a form of traditional herbal medicine. Several in vivo and in vitro studies point to s...

Differentiating organic and conventional sage by chromatographic and mass spectrometry flow injection fingerprints combined with principal component analysis.

High-performance liquid chromatography (HPLC) and flow injection electrospray ionization with ion trap mass spectrometry (FIMS) fingerprints combined with principal component analysis (PCA) were exami...

Identification of 1,8-Cineole, Borneol, Camphor, and Thujone as Anti-inflammatory Compounds in a Salvia officinalis L. Infusion Using Human Gingival Fibroblasts.

Drinking or gargling Salvia officinalis L. infusion (sage infusion) is thought to soothe a sore throat, tonsillitis, and inflamed, red gums, although structure-based scientific evidence for the key an...

Vaccines against tick-borne encephalitis: WHO position paper - Recommendations.

This article presents the WHO recommendations on the use of vaccines against tick-borne encephalitis excerpted from the recently published Vaccines against tick-borne encephalitis: WHO position paper....

Clinical Trials [ 5 Associated Clinical Trials listed on BioPortfolio]

Effects of Sage on Memory and Mental Performance in Alzheimer's Disease Patients

The purpose of this study is to determine the effectiveness of the herb sage in improving the mental function of individuals with Alzheimer's disease. Study hypothesis: The administration...

Clinical Trial for Assessment of Safety and Efficacy of a Echinacea/Sage Spray Compared to a Chlorhexidine/Lidocaine Spray in the Treatment of Acute Sore Throats

The aim of the study is to show non-inferiority of an echinacea/sage spray compared to a chlorhexidine/lidocaine-spray in the treatment of acute sore throat during five days of treatment....

The Systemic Lupus Erythematosus (SLE) Activity Gene Expression (SAGE) Study

The goal of this study is to enable the study sponsor to develop a new blood test method for clinicians to accurately predict which individuals with lupus will flare, when the flare will...

Skin Cleansing With Chlorhexidine to Decrease Hospital Acquired Infections

Patients in the intensive care unit are at risk for many infections because the severity of illness and the procedures necessary to care for them. This study is designed to look at a chan...

Effects of Aromatherapy on Childbirth

Aromatherapy is a form of complementary medicine that uses scented materials known as essential oils for the purpose of affecting a person's health or mood. Although aromatherapy has been...

Companies [ 23 Associated Companies listed on BioPortfolio]

Sage Science, Inc.

Sage Science develops game-changing instrument products for life science research and diagnostic laboratories. Sage Science is privately held. For more information visit www.sages...

Sage Science

Sage Science develops game-changing instrument products for life science research and diagnostic laboratories. Sage Science is privately held. For more information visit www.sages...

Sage Software Healthcare, LLC

For nearly 30 years, physicians have trusted Sage to deliver solutions that enable them to optimize their patients' experience while enhancing their bottom line. Sage Software Healthcare, LLC, provide...

Sage Software Healthcare, Inc.

Sage Software Healthcare, Inc., provides integrated electronic health records, EDI applications and practice management systems to thousands of ambulatory care practices throughout North America. Thes...

Sage Bionetworks

Sage Bionetworks is a nonprofit medical research organization established in 2009 to develop a new paradigm for addressing the complexity of human biological information and the t...

More Information about "SAGE Therapeutics" on BioPortfolio

We have published hundreds of SAGE Therapeutics news stories on BioPortfolio along with dozens of SAGE Therapeutics Clinical Trials and PubMed Articles about SAGE Therapeutics for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of SAGE Therapeutics Companies in our database. You can also find out about relevant SAGE Therapeutics Drugs and Medications on this site too.

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