Puma Biotechnology, Inc. Company Profile
Puma Biotechnology, Inc. is a development stage biopharmaceutical company that acquires and develops innovative products for the treatment of various forms of cancer. The Company focuses on in-licensing drug candidates that are undergoing or have already completed initial clinical testing for the treatment of cancer and then seeks to further develop those drug candidates for commercial use. The Company is initially focused on the development of PB-272 (oral neratinib), a potent irreversible tyrosine kinase inhibitor, for the treatment of patients with HER2 positive metastatic breast cancer.
News Articles
[Puma Biotechnology] nets $129.7mm through first public stock sale
Oncology drug in-licenser [Puma Biotechnology Inc.] has netted $129.7mm through the company's first public stock sale since its October 2011 inception and reverse merger with a public shell. Puma sold...
[Puma Biotechnology] grosses $120mm through first public stock sale
Oncology drug in-licenser [Puma Biotechnology Inc.] has grossed $120mm through the company's first public stock sale since its October 2011 inception and reverse merger with a public shell. Puma sold...
Biotech rumor mill Is Puma Biotech primed for acquisition?
Puma Biotechnology is proposed as an acquisition target after its stock surges in recent trading. Puma’s experimental breast-cancer treatment is viewed so favorably that its shares fetch $822 millio...
Form 10: Public By Any Means Necessary
Oncology firm Puma Biotechnology Inc. is trying to follow in its sister company’s paw prints. Puma attracted crossover investors thanks in part to the prior success of its chairman and CEO Alan Auer...
Puma proposes to raise up to $86.3M, list on NYSE
Puma Biotechnology Inc. (OTCBB:PBYI) proposed to raise up to $86.3 million in a follow-on and move its listing to the New York Stock Exchange. The offering is underwritten by BofA Merrill Lynch and Le...
Puma Biotechnology Inc. (NYSE:PBYI) jumped $5.88 (36%) to $22.38 on its first day of trading Friday on the New York Stock Exchange after raising $120 million in a bumped-up follow-on. Puma sold 7.5 mi...
Puma sets share amount for follow-on
Puma Biotechnology Inc. (OTCBB:PBYI) said it plans to sell 5.3 million shares in its proposed follow-on and transition to the New York Stock Exchange. If sold at Puma's close of $15.50 on Monday, the...
Puma Biotechnology commences Phase III breast cancer trial of PB272
Development stage biopharmaceutical company Puma Biotechnology has commenced Phase III trial of PB272 (neratinib) in patients with third-line HER2-positive metastatic breast cancer.
Drugs and Medications
Korres Quercetin & Oak Day Cream for Normal to Dry Skin SPF 4
Bio-active anti-aging [S.I.P.R.E.S. SRL]
Bio-Active Anti-Aging Cream Multi-Protection Daily Renewal SPF 15 Advanced Double Lifting Effect
Biodynamic skin [S.I.P.R.E.S. SRL]
Biodynamic Skin Solution
PubMed Articles
MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma.
ABSTRACT: BACKGROUND: MiR-221 and miR-222 (miR-221/222) are frequently up-regulated in various types of human malignancy including glioblastoma. Recent studies have reported that miR-221/222 regulate...
BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program.
Although the proteins BAX and BAK are required for initiation of apoptosis at the mitochondria, how BAX and BAK are activated remains unsettled. We provide in vivo evidence demonstrating an essential...
DNA damaging chemotherapy is the backbone of cancer treatment, although it is not clear how such treatments kill tumor cells. In non-transformed lymphoid cells, the combined loss of two pro-apoptotic...
JNK and Akt-mediated Puma Expression in the Apoptosis of Cisplatin-resistant Ovarian Cancer Cells.
BH3-only proteins have an important role in the cisplatin resistance of cells. However, the effect of BH3-only proteins on cisplatin-resistant ovarian cancer cells has not been thoroughly elucidated....
The protein Puma (p53-upregulated modulator of apoptosis) belongs to the BH3-only group of the Bcl-2 family and is a major regulator of apoptosis. Although the transcriptional regulation of Puma is cl...
Clinical Trials
A Pilot Scheme - Specimen Collection of Health Management Center
Biomedical and biotechnology industry is internationally regarded as the most brilliant star performer of the future. The development of biomedical depends on a high quality academic resea...
In the laboratory, Kevetrin activates p53, a tumor suppressor protein that has an important role in protecting the body. p53 functions by activating proteins that repair DNA and kill cells...
This study will be a Phase I, randomized, double blind, safety and immunogenicity trial of the Vero cell based 116E neonatal rotavirus vaccine candidate strain in healthy non-malnourished...
Companies
Puma Biotechnology, Inc. is a development stage biopharmaceutical company that acquires and develops innovative products for the treatment of various forms of cancer. The Company...
Task Group Public Perceptions of Biotechnology
The Task Group on Public Perceptions of Biotechnology is one of the six Task Groups of the European Federation of Biotechnology. It was established in 1991, to increase public awareness and understand...
Missouri Biotechnology Association
The Missouri Biotechnology Association is focused on maintaining the growth of the biotechnology industry generated by the research and development communities of Missouri. While we have made great st...
Swiss Biotech Association (SBA)
The Swiss Biotech Association (SBA) is the national association representing biotechnology companies, academic institutions, regional biotechnology centres and related organisations throughout Switzer...
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