Ensemble Therapeutics Corporation Company Profile
Based in Cambridge, MA, Ensemble Therapeutics is deploying its proprietary chemistry platforms to develop a novel class of therapeutics known as âEnsemblinsâ. Ensemble is leveraging its macrocycle drug discovery expertise to fuel its proprietary drug candidate pipeline while also pursuing collaborations with pharmaceutical partners. Ensemble has established high-value partnerships including alliances with Bristol-Myers Squibb and Pfizer. Ensembleâs internal discovery and development efforts are focused on the key therapeutic areas of oncology and immuno-inflammatory diseases, with its lead program, a small molecule antagonist of Interleukin-17, a cytokine implicated in multiple inflammatory and autoimmune diseases, poised to enter development with an orally active candidate by the end of 2012. For more information, visit: www.ensembletx.com.
News Articles
Ensemble, Genentech Development Collaboration
Mass High Tech | Ensemble Therapeutics and Genentech are collaborating on macrocyclic drug candidates against targets identified by Genentech. The companies will use the Ensemblin collection of macro...
Ensemble, Boehringer in macrocycle discovery deal
Ensemble Therapeutics Corp. (Cambridge, Mass.) partnered with Boehringer Ingelheim GmbH (Ingelheim, Germany) to use Ensemble's Ensemblin technology to discover macrocyclic drug candidates against undi...
Latest News From "The Pink Sheet" DAILY - Ensemble And Genentech Partner Up
Ensemble and Genentech agree to develop macrocyclic drugs against a variety of targets in a deal that adds further value to the Ensemble platform
A Survey: Evaluation of Ensemble Classifiers and Data Level Methods to Deal with Imbalanced Data Problem in Protein-Protein InteractionsPages 1-9Author Seena Mary AugustySminu IzudheeAbstract Over th...
Ensemble Adds Genentech To Partner Roster
Ensemble and Genentech agree to develop macrocyclic drugs against a variety of targets in a deal that adds further value to the Ensemble platform.
Ensemble Therapeutics and Boehringer Ingelheim ink $186 milliion macrocycle drug pact
Ensemble Therapeutics announced the initiation of a research collaboration with Boehringer Ingelheim to discover drug candidates of a novel class of small molecule drugs, called macrocycles, against s...
Ensemble rides macrocycle interest to fourth major deal, with B-Ingelheim
Ensemble Therapeutics has entered into an agreement to discover macrocyclic drug candidates against "several high-value pharmaceutical targets" specified by Boehringer Ingelheim, marking the fourth ma...
Genentech, Ensemble partner for macrocycle drug discovery
Ensemble Therapeutics has entered into its third major collaborative deal, with Genentech, a subsidiary of Roche, to support a proprietary drug discovery platform. The two plan to work together on...
Drugs and Medications
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PubMed Articles
New terphenyl based mercury ensemble for detection of acetate ions in a plasma like system.
A new terphenyl based chemosensor 3 has been designed and synthesized. The binding behavior of 3 and its chemosensing ensemble 3-Hg toward various anions (F(-), Cl(-), Br(-), I(-), HSO(4)(-), H(2)PO(4...
We present a theoretical study on the performance of ensemble docking methodologies considering multiple protein structures. We perform a theoretical analysis of pose prediction experiments which is c...
Utilizing experimental data for reducing ensemble size in flexible-protein docking.
Efficient and sufficient incorporation of protein flexibility into docking is still a challenging task. Docking to an ensemble of protein structures has proven its utility for docking, but using a lar...
Reexamining the possible benefits of visual crowding: dissociating crowding from ensemble percepts.
Peripheral objects and their features become indistinct when closely surrounding but nonoverlapping objects are present. Most models suggest that this phenomenon, called crowding, reflects limitations...
Potential and limitations of ensemble docking.
A major problem in structure-based virtual screening applications is the appropriate selection of a single or even multiple protein structures to be used in the virtual screening process. A priori it...
Clinical Trials
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Companies
Ensemble Discovery Corporation
Based in Cambridge, MA, Ensemble Discovery Corporation is deploying its proprietary chemistry platforms to develop a novel class of therapeutics known as âEnsemblinsâ. E...
Ensemble Therapeutics Corporation
Based in Cambridge, MA, Ensemble Therapeutics is deploying its proprietary chemistry platforms to develop a novel class of therapeutics known as âEnsemblinsâ. Ensemble i...
ArtusLabs is a business intelligence and document management company focused on providing Web 2.0 enabled software solutions to life science organizations. Its flagship product, E...
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