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S*BIO Pte Ltd Company Profile

21:00 EDT 29th May 2016 | BioPortfolio

S*BIO is a privately-held biotech company focused on the research and clinical development of novel targeted small molecule drugs for the treatment of cancer with leading programs around histone deacetylases (HDAC) and kinases. S*BIO's lead candidate, SB939, entered the clinic in 2007. SB1518, S*BIO's potent and orally-active JAK2 inhibitor, entered the clinic in 2008 and has received orphan drug designation from the U.S. FDA. S*BIO has entered into a development collaboration, and option & license agreement with Onyx Pharmaceuticals, Inc. to develop and commercialize SB1518 and its other novel JAK2 inhibitor, SB1578. S*BIO's SB1317, a novel multikinase inhibitor, is in pre-clinical development and under a worldwide exclusive license with Tragara Pharmaceuticals, Inc. for its development and commercialization.


News Articles [528761 Results]

Impax Laboratories Receives Form 483 Following FDA Inspection

FDA issues a Form 483 following inspection of Impax Laboratories' Hayward, CA facility. read more

Beyond the Crisis

First published in 1994, this volume discusses the nature of health care reform and the capacity for medical excellence within the context of such reform.

Interferon-Inducible Protein 10 Is A Potent Inhibitor Of Angiogenesis

Human interferon inducible protein 10 (IP-10) is a member of the chemokine family of molecules. It is a secreted protein with a molecular weight of approximately 8.6 kD. Previous work has demonstrated...

A Gene Encoding a Human Reduced Folate Carrier (RFC) and Methods for the Treatment of Methotrexate-Resistant, Transport-Deficient Cancer Cells

Methotrexate (MTX), a folate agonist that inhibits the cellular enzyme dihydrofolate reductase, is effective for the treatment of several types of cancer including non-Hodgkin's lymphoma, childhood ac...

Janus Family Kinases (JAK) And Identification Of Immune Modulators

This technology relates to an isolated polynucleotide encoding the JAK-3 protein. JAK-3 is a protein tyrosine kinase having a molecular weight of approximately 116 kDa, lacks SH2 or SH3 domains, and i...

Science-Based Economic Development

Key elements in science-based development.

T-Cell Receptors And Their Use In Therapeutic And Diagnostic Methods

Tumor infiltrating lymphocytes (TIL) play an important role in tumor regression. TIL cells that recognize a variety of specific tumor antigens have been identified. This invention embodies nucleic aci...

Allelic Variation of the Serotonin 5HT7 Receptor

The 5HT7 serotonin receptor is structurally distinct from known serotonin receptors and exhibits a high affinity for serotonin and several antipsychotic and antidepressant drugs. The neurotransmitter...

Clinical Trials [96237 Results]

The Utility of Peri-operative Arnica Montana for Reduction of Ecchymosis in Rhinoplasty Surgery

Arnica montana is a homeopathic drug that is made in accordance with the official methods of the Homeopathic Pharmacopoeia of the United States (HPUS) and is commonly used by cosmetic surg...

Pharyngeal Size in Patients With Obstructive Tonsils Under Orthodontic Treatment

Enlarged tonsils and malocclusion has relationship with sleep disturbance in children. The consequences of these features can include aggravation of craniofacial growth such that the devel...

The Biology of Chronic Preconditioning: Genomic and Physiologic Mechanisms of Response

The purpose of this study is to assess the effects of repeated RIPC and exercise, on exercise performance, skeletal muscle responses and circulating cellular and humoral biology in humans

Pilot Study of Raltegravir Lipodystrophy IISP

The substitution of raltegravir for the NRTIs will result in some reversal of the long term adverse effect of lipodystrophy (specifically peripheral lipoatrophy) that is associated with th...

Esophagoscopy in Evaluating Treatment in Patients With Stage I-IV Head and Neck Cancer Who Are Undergoing Radiation Therapy and/or Chemotherapy

Brief Summary: RATIONALE: Comparing results of diagnostic procedures, such as esophagoscopy, done before and after radiation therapy and/or chemotherapy may help doctors predict a patient...

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