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NAT2


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Gene DB Home
Symbol:NAT2
Name(s):N-acetyltransferase 2 (arylamine N-acetyltransferase)
Type:protein-coding
Organism:Homo sapiens
Synonyms:AAC2
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18199719 Observational study of gene-disease association. (HuGE Navigator)
18207572 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18258609 Observational study of gene-disease association. (HuGE Navigator)
18262724 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18264785 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18268115 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
18287869 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18330759 Observational study of gene-disease association. (HuGE Navigator)
18349284 Observational study of gene-disease association. (HuGE Navigator)
18023090 The haplotypes, NAT2 4 and NAT2 6A, are useful new biomarkers for predicting anti-tuberculosis drug-induced hepatotoxicity.

View more information from publications.

Recent Publications on NAT2:

Pubmed Logo
Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis of the proximal conserved residue, Tyr190.
Arylamine N-acetyltransferases (NATs) play an important role in both the...
29th October, 2009
Department of Medicinal Chemistry, University of Minnesota, Minneapolis, FEBS J. 2009 Oct 23.
DOI Direct Link
Isoform-Selective Inactivation of Human Arylamine N-Acetyltransferases by Reactive Metabolites of Carcinogenic Arylamines.
Human arylamine N-acetyltransferases (NATs) are expressed as two...
22nd October, 2009
Department of Medicinal Chemistry, University of Minnesota, 308 Harvard Chem Res Toxicol. 2009 Oct 20.
DOI Direct Link
Testing in semiparametric models with interaction, with applications to gene-environment interactions.
Motivated from the problem of testing for genetic effects on complex...
20th October, 2009
Texas A&M University, College Station, USA. J R Stat Soc Series B Stat Methodol. 2009 Jan 1;71(1):75-96.
DOI Direct Link
Pharmacogenetics of Phase I and Phase II Drug Metabolism.
Genetic variation in the receptors and other intracellular targets that...
20th October, 2009
Faculty of Pharmacy, University of Sydney, Sydney, Australia. Curr Pharm Des. 2009 Oct 15.
Effects of genetic polymorphisms of N-Acetyltransferase on trichloroethylene-induced hypersensitivity dermatitis among exposed workers.
The hypersensitivity dermatitis induced by trichloroethylene (TCE)...
17th October, 2009
National Institute for Occupational Health and Poison Control, Chinese Ind Health. 2009 Oct;47(5):479-86.

View more research publications.

BioNews Results for NAT2

: RSS Logo
BioPortfolio Logo
Genetic Variations in Xenobiotic Metabolic Pathway Genes, Personal Hair Dye Use, and Risk of Non-Hodgkin Lymphoma
MDLinx:  Oct 13 2009 10:52AM Matching: nat2
Genetic mutation a strong indicator of age-related hearing loss risk
PhysOrg.com:  Oct 8 2009 9:00AM Matching: nat2
Genetic mutation a strong indicator of age-related hearing loss risk
Genetic Engineering News:  Oct 6 2009 6:25PM Matching: nat2

Clinical Trials:

Clinical Trials Logo
Isoniazid Dose Adjustment According to NAT2 Genotype (IDANAT2)

Patents:

Patents logo
US Patent No.Title
6346374 Nucleic acid molecules encoding GLUTX and uses thereof
6844189 Chromosome 17P-linked prostate cancer susceptibility gene
6906957 Sensing circuitry for reading and verifying the contents of electrically programmable and erasable non-volatile memory cells, useful in low supply-voltage technologies
6933115 Nucleic acid molecules encoding GLUTX and uses thereof
6985920 Method and system for determining intra-session event correlation across network address translation devices

View more patents.

NAT2 results (if any) from reagent suppliers

Google CSE Logo
NAT2 antibodies: Signal Transduction > Metabolism > Drug ...
NAT2 antibodies. ... Applications (see key) & Reactivity (see key). Image Abreview Publication. ab50413 · NAT2 antibody. Fast Track. Goat polyclonal ...
http://www.abcam.com/index.html?t=203494&pt=1&c=3613&ei=&mu=...

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NAT-1/2 (G-5) Antibody sc-137204
Western blot analysis of NAT-2 expression in non-transfected: sc-117752 (A) and mouse NAT-2 transfected: sc-121945 (B) 293T whole cell lysates. ...
http://www.scbt.com/datasheet-137204-nat-1-2-g-5-antibody.ht...

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NAT2 proteins and peptides: Signal Transduction > Metabolism ...
NAT2 proteins and peptides. ... NAT2 protein (Active). FuncS. Terms and conditions · Legal · Privacy policy · Investor relations · Contact us · Blog ...
http://www.abcam.com/index.html?t=203494&pt=2&c=3613&ei=&mu=...

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NAT-1/2 (C-16) Antibody sc-47219
goat polyclonal IgG, 200µg/ml; epitope mapping at the C-terminus of NAT-1 of human origin; recommended for detection of NAT-1 of human origin, NAT-2 of ...
http://www.scbt.com/datasheet-47219-nat-1-2-c-16-antibody.ht...

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Bioluminescent N-Acetyl Transferase-2 Enzyme Assay Using a Novel ...
Luciferin-NAT2 is a specific substrate for this enzyme and shows little to no ... Luciferin-NAT2 is used in a luminogenic assay that correlates light output
...
http://www.promega.com/enotes/applications/ap0098.htm...

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NAT-2 siRNA (h) sc-61156
Click here for details. suitable control antibody: NAT-2 (C-17): sc-47227; sqRT- PCR Primer also available: NAT-2 (h)-PR: sc-61156-PR, 20 µl ...
http://www.scbt.com/ko/datasheet-61156-nat-2-sirna-h.html...

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Protein Modification / Acetylation - Protein Modification Antibody
AT2923a, MTA1 monoclonal antibody (M02), ELISA,IF,S-ELISA,WB-Ce, H. AT2973a, NAT2 monoclonal antibody (M01), ELISA,WB-Re,WB-Tr, H ...
http://www.abgent.com/products/category/protein_modification...

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