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AKT3
| Symbol: | AKT3 | | Name(s): | v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | DKFZP434N0250, PKB-GAMMA, PKBG, PRKBG, RAC-PK-gamma, RAC-gamma, STK-2 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17895832 |
PKB[alpha] and/or PKB[gamma] and not PKB[beta] alone are involved in gemcitabine resistance mechanisms. |
| 17668379 |
AKT3 represents an excellent candidate for developmental human MIC and ACC, and we suggest that haploinsufficiency causes both postnatal MIC and ACC. |
| 12663464 |
results show that a defect in the ability of insulin to activate Akt-2 and -3 may explain the impaired insulin-stimulated glucose transport in insulin resistance |
| 15466193 |
Targeted reduction of Akt3 activity with siRNA or by expressing active PTEN protein stimulated apoptotic signaling, which reduced cell survival by increasing apoptosis rates thereby inhibiting melanoma tumor development. |
| 15698844 |
activation of Akt signaling results in progression from adaptive to maladaptive cardiac hypertrophy |
| 15579468 |
Rac1, PI3 kinase, and Akt3 have roles in an anti-apoptotic pathway triggered by ALS2 that antagonizes SOD1 mutant-induced motoneuronal cell death |
| 12692267 |
The regulation by Akt3 was found to be due to two specific regions in the Fra-1 regulatory sequence which match Sp1 consensus sites |
| 17178867 |
AKT3 is highly expressed in 19 of 92 primary ovarian tumors, consistent with AKT3 playing a key role in the genesis of at least one subset of ovarian cancers. |
| 15987444 |
in breast cancer patients, Akt activation is associated with tumour proliferation and poor prognosis, particularly in the subset of patients with ErbB2-overexpressing tumours |
| 15543611 |
Dysregulation of the PI 3-K/AKT/PTEN pathway may contribute to early head neck squamous cell carcinoma tumorigenesis. | →View more information from publications. |
Recent Publications on AKT3: |  |
Differential dependence of HIF1alpha and HIF2alpha on mTORC1 and mTORC2.
Constitutive expression of hypoxia-inducible factor (HIF) has been... | 24th October, 2008
| Biological Sciences Department, Hunter College of CUNY, New York, NY
| J Biol Chem. 2008 Oct 22.
DOI Direct Link |
Targeting V600EB-Raf and Akt3 using nanoliposomal-small interfering RNA inhibits cutaneous melanocytic lesion development.
Most events promoting early melanoma development are yet to be identified,... | 15th October, 2008
| Department of Pharmacology, The Pennsylvania State University, Hershey,
| Cancer Res. 2008 Sep 15;68(18):7638-49.
DOI Direct Link |
Activation and Membrane Binding of Retinal Protein Kinase Balpha/Akt1 is Regulated through Light-Dependent Generation of Phosphoinositides.
Abstract Akt is a phospholipid-binding protein and the downstream effector... | 1st October, 2008
| Department of Cell Biology, University of Oklahoma Health Sciences Center,
| J Neurochem. 2008 Sep 24.
DOI Direct Link |
A novel AKT3 mutation in melanoma tumours and cell lines.
Recently, a rare activating mutation of AKT1 (E17K) has been reported in... | 25th September, 2008
| Department of Melanoma Medical Oncology, The University of Texas MD
| Br J Cancer. 2008 Oct 21;99(8):1265-8. Epub 2008 Sep 23.
DOI Direct Link |
VEGF stimulation of mitochondrial biogenesis: requirement of AKT3 kinase.
The growth factor, vascular endothelial growth factor (VEGF), induces... | 25th September, 2008
| Department of Cell Biology and Anatomy, Medical University of South
| FASEB J. 2008 Sep;22(9):3264-75. Epub 2008 Jun 4.
DOI Direct Link |
→View more research publications. |
AKT3 results (if any) from reagent suppliers | 
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AKT3 antibody (ab5922) datasheet | Abcam
Rabbit polyclonal to AKT3. Akt, protein kinase B (PKB), is a serine/threonine kinase which is involved in many cellular signaling pathways and acts as a ...
http://www.abcam.com/index.html?datasheet=5922...
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AKT3 Antibody V-akt murine thymoma viral oncogene homolog 3
AKT3 antibody can be stored at 4C for short term (weeks) and -20C for long term. ,
http://www.prosci-inc.com/shop/catalog1/AKT3-Antibody-p-1660...
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AKT3 antibody, AKT3 antibody Antibody, Rabbit IgG Polyclonal Antibody
Buy quality rabbit AKT3 antibody (interacts with cross-reacts with human mouse and rat.), anti-AKT3, AKT3 antibody antibody, rabbit igg polyclonal antibody,
...
http://www.genwaybio.com/product_info.php?products_id=197487...
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Akt3 (4H23) Antibody sc-70338
Akt3 (4H23) Antibody sc-70338 Akt3 (4H23) Antibody sc-70338. ... mouse monoclonal IgG1, 100µg/ml; raised against amino acids 119-136 of Akt3 of human
origin ...
http://www.scbt.com/datasheet-70338-akt3-4h23-antibody.html...
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Akt3 Monclonal Antibody also designated protein kinase B gamma or ...
Akt3 monclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. ...
http://www.prosci-inc.com/shop/catalog1/Akt3-Monclonal-Antib...
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AKT3 protein, AKT3 protein recombinant protein
Buy quality AKT3 protein (sf9 insect cells), AKT3, AKT3 protein recombinant protein, (n/an/a). V-akt murine thymoma viral oncogene homolog 3 isoform 1, ...
http://www.genwaybio.com/product_info.php?products_id=55012...
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Human Akt3 MAb (Clone 199864)
viral oncogene homolog 3 (Akt3), also known as protein kinase B gamma (PKBγ) and ... The antibody detects endogenous human Akt3. Mouse and rat Akt3 ...
http://www.rndsystems.com/pdf/mab1463.pdf...
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Akt3 (C-14) Antibody sc-11520
See how others have used Akt3 (C-14): sc-11520 and or Akt3 (C-14) ... Western blot analysis of Akt3 expression in insulin treated NIH/3T3 whole cell lysate.
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http://www.scbt.com/datasheet-11520-akt3-c-14-antibody.html...
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A5107 Anti AKT3 401 415 antibody produced in rabbit IgG fraction ...
A5107 Anti-AKT3 (401-415) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution.
http://www.sigmaaldrich.com/catalog/search/ProductDetail/SIG...
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Akt3 (M-14) Antibody sc-11521
See how others have used Akt3 (M-14): sc-11521 and or Akt3 (M-14) antibody ... Western blot analysis of Akt3 expression in mouse brain tissue extract. ...
http://www.scbt.com/datasheet-11521-akt3-m-14-antibody.html...
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