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KCNE3
| Symbol: | KCNE3 | | Name(s): | potassium voltage-gated channel, Isk-related family, member 3 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | DKFZp781H21101, HOKPP, MGC102685, MGC129924, MiRP2 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18209471 |
Abnormalities in the KCNE3 gene is a potential genetic risk factor for initiation and/or maintenance of atrial fibrillation. |
| 14504341 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15212652 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17495071 |
Up-regulation and incrased activity of KV3.4 channels and their accessory subunit Mirp2 induced by amyloid peptide are involved in apoptotic neuronal death. |
| 11956246 |
Ectopic expression of KCNE3 accelerates cardiac repolarization and abbreviates the QT interval. |
| 16782062 |
KCNE3 also inhibits currents generated by Kv4.3 in complex with the accessory subunit KChIP2 |
| 15037716 |
The authors found MiRP2-R83H in 3 of 321 control subjects and in 5 unaffected related individuals. Provocation of an unaffected carrier with glucose or KCl did not induce weakness. |
| 16449802 |
The characterization of a missense mutation in MiRP2 that affects its phosphorylation and consequent interactions with Kv3.4 is reported. |
| 16374062 |
The result indicates that 112G/A SNP in the KCNE1 gene and 198T/C SNP in the KCNE3 gene could determine an increased susceptibility to develop MD. |
| 16308347 |
interaction of MiRP2-72 with KCNQ1-338; and MinK-59,58 with KCNQ1-339, 340 | →View more information from publications. |
Recent Publications on KCNE3: |  |
Functional effects of KCNE3 mutation and its role in the development of Brugada syndrome.
INTRODUCTION: The Brugada Syndrome (BrS), an inherited syndrome associated... | 29th October, 2009
| Department of Pharmacology, School of Medicine, Universidad Complutense,
| Circ Arrhythm Electrophysiol. 2008 Aug;1(3):209-18.
DOI Direct Link |
Novel female sex-dependent actions of oestrogen in the intestine.
The intestine is an oestrogen responsive organ and circulatory oestrogens... | 3rd September, 2009
| Royal College of Surgeons in Ireland, Department of Molecular Medicine,
| J Physiol. 2009 Nov 1;587(Pt 21):5039-44. Epub 2009 Sep 1.
DOI Direct Link |
Serum- and glucocorticoid-inducible kinases (SGK) regulate KCNQ1/KCNE potassium channels.
The stress reaction includes the release of stress hormones such as... | 2nd September, 2009
| Department of Physiology I, University of Tubingen, Tubingen, Germanya.
| Channels (Austin). 2009 Mar-Apr;3(2):88-90. Epub 2009 Mar 4.
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Distinct subdomains of the KCNQ1 S6 segment determine channel modulation by different KCNE subunits.
Modulation of voltage-gated potassium (KV) channels by the KCNE family of... | 19th August, 2009
| Division of Genetic Medicine, Department of Medicine, Center for
| J Gen Physiol. 2009 Sep;134(3):207-17. Epub 2009 Aug 17.
DOI Direct Link |
KCNE1 and KCNE3 beta-subunits regulate membrane surface expression of Kv12.2 K(+) channels in vitro and form a tripartite complex in vivo.
Voltage-gated potassium channels that activate near the neuronal resting... | 23rd July, 2009
| Department of Cell Biology, Institute for Childhood and Neglected
| PLoS One. 2009 Jul 22;4(7):e6330.
DOI Direct Link |
→View more research publications. |
KCNE3 results (if any) from reagent suppliers | 
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KCNE3 (N-18) Antibody sc-10647
See how others have used KCNE3 (N-18): sc-10647 antibody and or KCNE3 (N-18) ... Western blot analysis of KCNE3 expression in HeLa whole cell lysate. ...
http://www.scbt.com/datasheet-10647-kcne3-n-18-antibody.html...
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Anti-Potassium Channel KCNE3 (MiRP2) (K0140) - Data Sheet
human KCNE3 protein. The antibody will also work with rat and mouse samples. ... with rat KCNE3 (Gene ID 63883). The antibody is used ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...
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KCNE3 (H-80) Antibody sc-28796
KCNE3 shRNA (h) Lentiviral Particles, sc-35743-V, 200 µl ... Western blot analysis of human recombinant KCNE3 fusion protein. Download ...
http://www.scbt.com/datasheet-28796-kcne3-h-80-antibody.html...
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K+ Channels in Cardiomyocytes
APC-054. Anti-KCNE3. APC-118. Anti-Kvβ2. APC-117. Anti-sloβ1 (KCNMB1). APC-036. Anti-sloβ2 (KCNMB2). APC-034. Anti-sloβ4 (KCNMB4). APC-061 ...
http://www.alomone.com/system/UpLoadFiles/DGallery/Docs/K%20...
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KCN Antibody / KCN Antibodies
KCNE3 (H-80) Antibody, sc-28796, rabbit IgG, 1-80 (h), WB, IP, IF, ELISA, m, r, h. KCNE3 (N-18) Antibody, sc-10647, goat IgG, N-terminus (h), WB, IP, IF, ...
http://www.scbt.com/table-kcn.html...
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Abcam antibodies and reagents product map
... Insulin degrading enzyme / IDE proteins and peptides (5) · KCNC4 antibodies (2) · KCNE3 antibodies (1) · Kallikrein 6 antibodies (4) ...
http://www.abcam.com/index.html?cl=248&pageconfig=productmap...
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KCNE3 siRNA (h) sc-35743
Click here for details. suitable control antibody: KCNE3 (N-18): sc-10647; sqRT- PCR Primer also available: KCNE3 (h)-PR: sc-35743-PR, 20 µl ...
http://www.scbt.com/ko/datasheet-35743-kcne3-sirna-h.html...
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