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CHAF1A


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Symbol:CHAF1A
Name(s):chromatin assembly factor 1, subunit A (p150)
Type:protein-coding
Organism:Homo sapiens
Synonyms:CAF-1, CAF1, CAF1B, CAF1P150, MGC71229, P150
Links: Pubmed, Entrez Gene, GeneCards, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18270339 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
16826239 p150 was efficiently phosphorylated by Cdc7-Dbf4 kinase.
17099699 ACF generates the characteristic 50- to 60-base-pair internucleosomal spacing in silent chromatin by kinetically discriminating against shorter linker DNAs
15067324 Altered mRNA expression is associated with prostate cancer recurrence.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDmethyl-CpG binding domain protein 1 isoform 1chromatin assembly factor 1, subunit A--Pubmed
HPRDmethyl-CpG binding domain protein 1 isoform 1chromatin assembly factor 1, subunit A--Pubmed
BINDmethyl-CpG binding domain protein 1 isoform PCM1chromatin assembly factor 1, subunit AMBD1 interacts with CAF-1.-Pubmed
HPRDproliferating cell nuclear antigenchromatin assembly factor 1, subunit A--Pubmed
HPRDchromatin assembly factor 1 subunit Bchromatin assembly factor 1, subunit A--Pubmed
HPRDchromatin assembly factor 1 subunit Bchromatin assembly factor 1, subunit A--Pubmed
BINDhistone cluster 1, H3echromatin assembly factor 1, subunit ACAF-1 p150 interacts with H3.1. This interaction was modeled on a demonstrated interaction between human CAF-1 p150 and H3.1 from an unspecified species.-Pubmed
HPRDbromodomain adjacent to zinc finger domain 1Bchromatin assembly factor 1, subunit A--Pubmed
BINDSET domain, bifurcated 1chromatin assembly factor 1, subunit ASETDB1 interacts with CAF-1.-Pubmed
HPRDChromatin assembly factor 1 subunit Achromobox homolog 1--Pubmed

Recent Publications on CHAF1A:

Pubmed Logo
Comprehensive analysis of the role of DNA repair gene polymorphisms on risk of glioma.
Much of the variation in inherited risk of glioma is likely to be...
1st December, 2007
Section of Cancer Genetics, Institute of Cancer Research, 15 Cotswold Rd, Hum Mol Genet. 2008 Mar 15;17(6):800-5. Epub 2007 Nov 29.
DOI Direct Link

Patents:

Patents logo
US Patent No.Title
7371736 Gene expression profiling based identification of DKK1 as a potential therapeutic targets for controlling bone loss
7308364 Diagnosis of multiple myeloma on gene expression profiling
7157233 Methods and compositions for the detection of cervical disease

CHAF1A results (if any) from reagent suppliers

Google CSE Logo
CHAF1A chromatin assembly factor 1, subunit A (p150)
CHAF1A; CAF-1; CAF1; CAF1B; CAF1P150; MGC71229; P150. Other Designations. chromatin assembly factor I (150 kDa). Refseq ID(s). NM_005483. Accession No.(s) ...
http://www.sigmaaldrich.com/catalog/search/SIRNASearchGeneDe...

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Caf1p150 Antibody Bethyl Laboratories
The CAFI subunits include Caf1 (p150; CHAF1A), P50, and p60 (CHAF1B; MIM 601245). The CAFI complex plays an important role in histone octamer assembly ...
http://www.bethyl.com/go/?product/A301-482A/TreeKey=a4ddeb0a...

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Chaf1a chromatin assembly factor 1, subunit A (p150)
Official Symbol. Chaf1a. Species. Mus musculus. Entrez Gene ID. 27221. Alternate Symbol. Chaf1a; AL023013; AL024058; CAC1P; CAF-1; CHAF1A. Refseq ID(s) ...
http://www.sigmaaldrich.com/catalog/search/SIRNASearchGeneDe...

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Baculo-EZ Expression Ready Clones
Cdk7-HA, BVC-10463, $395.00. chicken c-src kinase (CSK), BVC-10015, $395.00. Chromatin assembly factor p150 (CHAF1A), BVC-10097, $395.00 ...
http://www.orbigen.com/dictionary/cat1068.htm...

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SH1811 MISSION shRNA Human Gene Family Set Bacterial Glycerol ...
... ATR(545), ATRX(546), BLM(641), BRCA1(672), BRCA2(675), BTG2(7832), C11orf30(56946), C1orf124(83932), CCNH(902), CDK7(1022), CHAF1A(10036), CHAF1B(8208), ...
http://www.sigmaaldrich.com/catalog/search/ProductDetail/SIG...

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