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ABCC9


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Symbol:ABCC9
Name(s):ATP-binding cassette, sub-family C (CFTR/MRP), member 9
Type:protein-coding
Organism:Homo sapiens
Synonyms:ABC37, CMD1O, FLJ36852, SUR2
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18239147 review the structure and function of ABC proteins and discuss SUR, its regulation of the K(ATP) channel, and its role in cardiovascular disease.
16563363 Observational study of gene-disease association. (HuGE Navigator)
16672225 Syntaxin-1A actions on sulfonylurea receptor 2A blocks acidic pH-induced cardiac K(ATP) channel activation
15034580 role of mutation in human dilated cardiomyopathy and effect on KATP channel gating
16563363 newly discovered 734Ile allele in ABCC9 might influence susceptibility to precocious myocardial infarct in our population
15339904 Syn-1A binds both NBFs of SUR1 and SUR2A but appears to exhibit distinct interactions with NBF2 of these SUR proteins in modulating the KATP channels in islet beta cells and cardiac myocytes
16267564 Syn-1A binds both NBFs of SUR1 and SUR2A but appears to exhibit distinct interactions with NBF2 of these SUR proteins in modulating the KATP channels in islet beta cells and cardiac myocytes
16820413 Results describe a new function of the Kir6.1-SUR2A complex, namely the regulation of paracellular permeability through tight junctions.
11825905 Assembly limits the pharmacological complexity of ATP-sensitive potassium channels
12934053 In corporal smooth muscle is composed of Kir6.1-Kir6.2 construct expressed with SUR2B.K(ATP) channel in corporal smooth muscle cells is composed of heteromultimers of Kir6.1 and Kir6.2 with the ratio of 3 : 1 or 4 : 0 and SUR2B.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDATP sensitive inward rectifier potassium channel 8ATP-binding cassette, sub-family C, member 9 isoform SUR2A--Pubmed
HPRDpotassium inwardly-rectifying channel J8ATP binding cassette, subfamily C, member 9--Pubmed
HPRDLactate dehydrogenase AATP-binding cassette, sub-family C, member 9 isoform SUR2A--Pubmed
HPRDlactate dehydrogenase AATP binding cassette, subfamily C, member 9--Pubmed

Recent Publications on ABCC9:

Pubmed Logo
Differential K(ATP) channel pharmacology in intact mouse heart.
Classically, cardiac sarcolemmal K(ATP) channels have been thought to be...
12th September, 2009
Department of Biomedical Engineering, Washington University, St. Louis, MO J Mol Cell Cardiol. 2009 Sep 8.
DOI Direct Link
Cardiac sarcolemmal K(ATP) channels: Latest twists in a questing tale!
Reconstitution of K(ATP) channel activity from coexpression of members of...
18th July, 2009
Department of Cell Biology and Physiology, Washington University School of J Mol Cell Cardiol. 2009 Jul 14.
DOI Direct Link
Differential structure of atrial and ventricular KATP: atrial KATP channels require SUR1.
The isoform-specific structure of the ATP-sensitive potassium (K(ATP))...
10th January, 2009
Department of Cell Biology and Physiology, Washington University School of Circ Res. 2008 Dec 5;103(12):1458-65. Epub 2008 Oct 30.
DOI Direct Link
Gene expression profiling of ABC transporters in dermal fibroblasts of pseudoxanthoma elasticum patients identifies new candidates involved in PXE pathogenesis.
Mutations in the ABCC6 gene, encoding the multidrug resistance-associated...
17th December, 2008
Institut fur Laboratoriums-und Transfusionsmedizin, Herz-und Lab Invest. 2008 Dec;88(12):1303-15. Epub 2008 Oct 20.
DOI Direct Link
Substrates and inhibitors of human multidrug resistance associated proteins and the implications in drug development.
Human contains 49 ATP-binding cassette (ABC) transporter genes and the...
10th October, 2008
Division of Chinese Medicine, School of Health Sciences, WHO Collaborating Curr Med Chem. 2008;15(20):1981-2039.

View more research publications.

Patents:

Patents logo
US Patent No.Title
7504225 Reagents and methods for use in cancer diagnosis, classification and therapy
7468244 Polymorphism detection and separation
7447594 Molecular cardiotoxicology modeling
7426441 Methods for determining renal toxins
7415358 Molecular toxicology modeling

View more patents.

ABCC9 results (if any) from reagent suppliers

Google CSE Logo
ABCC9 antibody (ab84299) | Abcam
Rabbit polyclonal to ABCC9. ABCC9 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across ...
http://www.abcam.com/ABCC9-antibody-ab84299.html...

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SUR-2B (C-15) Antibody sc-5793
Human, ABCC9, 10060, 12p12.1, NM_005691, NM_020297, NM_020298 · O60706 · 608569. Mouse, Abcc9, 20928, 6 G2, P70170, N/A. Ordering Information ...
http://www.scbt.com/datasheet-5793-sur-2b-c-15-antibody.html...

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All Neural Signal Transduction | Abcam
ABCC9 antibody. WB. Images. Rabbit polyclonal. Reacts with: Hu, Ms, Rat. ab42635 · ACCN1 antibody. WB. Images. Rabbit polyclonal. Reacts with: ...
http://www.abcam.com/index.html?c=1055...

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SUR-2 (H-80) Antibody sc-25684
Human, ABCC9, 10060, 12p12.1, NM_005691, NM_020297, NM_020298 · O60706 · 608569. Mouse, Abcc9, 20928, 6 G2, P70170, 없음. 주문정보 ...
http://www.scbt.com/ko/datasheet-25684-sur-2-h-80-antibody.h...

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Primary antibodies | Abcam
ABCC9 antibody. WB. Images. Rabbit polyclonal. Reacts with: Hu, Ms, Rat. ab77364 · ABCD1 antibody. WB, ELISA. Images. Goat polyclonal. Reacts with: ...
http://www.abcam.com/index.html?pageconfig=catalog_byproduct...

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Abcam antibodies and reagents product map
ABCB11 antibodies (1) · ABCB5 antibodies (2) · ABCC10 antibodies (1) · ABCC9 antibodies (1) · AE2 antibodies (1) · AE2 proteins and peptides (1) ...
http://www.abcam.com/index.html?cl=2105&pageconfig=productma...

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