Wednesday November 25 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

ADAM8


Suggest Content
Advertise Here
Gene DB Home
Symbol:ADAM8
Name(s):ADAM metallopeptidase domain 8
Type:protein-coding
Organism:Homo sapiens
Synonyms:CD156, MGC134985, MS2
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17979891 ADAM8 is overexpressed in pancreatic ductal adenocarcinoma, influences cancer cell invasiveness and correlates with reduced survival.
17339047 ADAM8 may contribute to the airway remodeling process that occurs with asthma progression.
17548643 All these data support a potential relevant role for ADAM-8 in the function of neutrophils during inflammatory response.
15623614 Overexpression of ADAM8 is associated with lung cancer progression

Recent Publications on ADAM8:

Pubmed Logo
ADAM8/MS2/CD156, an emerging drug target in the treatment of inflammatory and invasive pathologies.
While it is highly accepted that ADAM family members with ubiquitous...
23rd October, 2009
King's College London, Department of Biochemistry, London, United Kingdom. Curr Pharm Des. 2009;15(20):2272-81.
ADAM-8 isolated from human osteoarthritic chondrocytes cleaves fibronectin at Ala(271).
OBJECTIVE: Fibronectin fragments are thought to play a critical role in...
20th October, 2009
Pfizer Global Research and Development, 700 Chesterfield Parkway, Arthritis Rheum. 2009 Sep;60(9):2704-13.
DOI Direct Link
Autoactivation of human ADAM8: a novel pre-processing step is required for catalytic activity.
Members of the ADAM (a disintegrin and metalloproteinase) family of...
9th October, 2009
Pfizer Global Research and Development, Chesterfield, MO 63017, USA. Biosci Rep. 2009 Aug;29(4):217-28.
DOI Direct Link
ADAM8 substrate specificity: influence of pH on pre-processing and proteoglycan degradation.
A disintegrin and metalloprotease-8 (ADAM8) is thought to play a role in...
22nd September, 2009
Pfizer Inc., Global Research and Development, St. Louis Laboratories, St. Arch Biochem Biophys. 2009 Nov;491(1-2):106-11. Epub 2009 Sep 18.
DOI Direct Link
Reduced incidence and severity of experimental autoimmune arthritis in mice expressing catalytically inactive A disintegrin and metalloproteinase 8 (ADAM8).
A disintegrin and metalloproteinase 8 (ADAM8), a catalytically active...
10th September, 2009
Pfizer Global Research and Development, Chesterfield, MO 63017, USA. Clin Exp Immunol. 2009 Nov;158(2):246-56. Epub 2009 Aug 6.
DOI Direct Link

View more research publications.

BioNews Results for ADAM8

: RSS Logo
BioPortfolio Logo
Arthritis Immunology: New arthritis immunology research from Pfizer Inc. described
NewsRX:  Oct 22 2009 4:23AM Matching: adam8

Patents:

Patents logo
US Patent No.Title
7612181 Dual variable domain immunoglobulin and uses thereof
7251568 Methods and compositions for regulating bone and cartilage formation
7235358 Methods and compositions for diagnosing and monitoring transplant rejection
7229760 mRNA amplification
7226596 Compositions and methods for the treatment of tumors

View more patents.

ADAM8 results (if any) from reagent suppliers

Google CSE Logo
ADAM8 Antibody (CT) MS2 / ADAM8 / CD156
ADAM8 antibody was raised against a synthetic peptide near the C-terminus of ADAM8.,
http://www.prosci-inc.com/shop/catalog1/ADAM8-Antibody-p-260...

Thumbshot
Anti-ADAM8 Polyclonal Antibody
Polyclonal Antibody against ADAM8 for use in Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...

Thumbshot
ADAM8 antibodies: Signal Transduction > Cytoskeleton / ECM ...
ADAM8 antibodies. ... ADAM8 antibody - Aminoterminal end. WB. Customer Abreviews : 2 stars (out of 5) ... ADAM8 antibody - Carboxyterminal end ...
http://www.abcam.com/index.html?t=9088&pt=1&c=3657&ei=&mu=ra...

Thumbshot
human ADAM8/CD156 DuoSet
Domain 8 (ADAM8). DuoSets are designed for the .... be linearized by plotting the log of the ADAM8 ... when using this human ADAM8 DuoSet. The standard ...
http://www.rndsystems.com/pdf/dy1031.pdf...

Thumbshot
ADAM8 peptide (813-824) (ab22912) | Abcam
ADAM8 peptide (813-824). Members of ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains.
http://www.abcam.com/ADAM8-peptide-813-824-ab22912.html...

Thumbshot
ADAM Antibody / ADAM Antibodies
ADAM8 (N-17) Antibody, sc-15499, goat IgG, N-terminus (h), WB, IP, IF, .... ADAM8 (MD158) Antibody, sc-73688, mouse IgG1, 156-653 (h), discontinued, human
...
http://www.scbt.com/table-adam.html...

Thumbshot
ADAM8 proteins and peptides: Signal Transduction > Cytoskeleton ...
ADAM8 proteins and peptides. ... ADAM8 peptide (Carboxyterminal end). WB, ELISA. ab41160 · ADAM8 peptide (Propeptide domain). WB, ELISA ...
http://www.abcam.com/index.html?t=9088&pt=2&c=3657&ei=&mu=ra...

Thumbshot

Search Bioportfolio and other Life Science Sites for ADAM8, or search for ADAM8 on BioPortfolio's antibody search engine.
This page has been viewed 115 times
Recent Search Terms used to find this page:
ADAM-8 | Hypoxia-dependent expression of ADAM8 in human pancreatic cancer cell lines. | .


Resources from the NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.