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NAMPT


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Gene DB Home
Symbol:NAMPT
Name(s):nicotinamide phosphoribosyltransferase
Type:protein-coding
Organism:Homo sapiens
Synonyms:1110035O14Rik, DKFZP666B131, MGC117256, PBEF, PBEF1, VF
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17931620 Rosuvastatin induced a significant decrease in plasma visfatin levels in patients with primary hyperlipidemia.
18270432 Observational study of gene-disease association. (HuGE Navigator)
16636125 Observational study of gene-disease association. (HuGE Navigator)
16922702 Observational study of gene-disease association. (HuGE Navigator)
17003359 Observational study of gene-disease association. (HuGE Navigator)
17189536 Observational study of gene-disease association. (HuGE Navigator)
17261426 Observational study of gene-disease association. (HuGE Navigator)
17512309 Observational study of gene-disease association. (HuGE Navigator)
17904242 Circulating visfatin may be related with some proinflammatory condition even in a nondiabetic state
17429683 PBEF/NAMPT/visfatin level is an indicator of beneficial lipid profile in non-diabetic Caucasian subjects

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDinsulin-like growth factor 1 receptor precursor-PBEF interacts with IGF-IR. This interaction was modeled on a demonstrated interaction between PBEF from an unspecified species and human IGF-IR.-Pubmed
BINDinsulin receptor-PBEF interacts with IR.-Pubmed

Recent Publications on NAMPT:

Pubmed Logo
SIRT1-dependent Regulation of Chromatin and Transcription: Linking NAD(+) Metabolism and Signaling to the Control of Cellular Functions.
Sirtuins comprise a family of NAD(+)-dependent protein deacetylases and...
3rd November, 2009
Department of Molecular Biology and Genetics, Cornell University, Ithaca, Biochim Biophys Acta. 2009 Oct 29.
DOI Direct Link
Nicotinamide phosphoribosyltransferase regulates cell survival through autophagy in cardiomyocytes.
Nicotinamide adenine dinucleotide (NAD(+)) acts as a transfer molecule for...
27th October, 2009
Department of Cell Biology and Molecular Medicine, Cardiovascular Research Autophagy. 2009 Nov 8;5(8).
Dysregulation of myeloid-specific transcription factors in congenital neutropenia.
Severe congenital neutropenia (CN) is a heterogeneous hematopoietic...
24th October, 2009
Department of Molecular Hematopoiesis, Hannover Medical School, Hannover, Ann N Y Acad Sci. 2009 Sep;1176:94-100.
DOI Direct Link
Polyploidy impairs human aortic endothelial cell function and is prevented by nicotinamide phosphoribosyltransferase.
Polyploid endothelial cells are found in aged and atherosclerotic...
23rd October, 2009
1The University of Western Ontario. Am J Physiol Cell Physiol. 2009 Oct 21.
DOI Direct Link
Visfatin (Nampt) and Ghrelin as Novel Markers of Carotid Atherosclerosis in Patients with Type 2 Diabetes.
OBJECTIVE: Visfatin (nampt) and ghrelin are the most recently identified...
17th October, 2009
First Department of Internal Medicine, "Hippokratio" General Hospital of Exp Clin Endocrinol Diabetes. 2009 Oct 15.
DOI Direct Link

View more research publications.

BioNews Results for NAMPT

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Metabolomics Used to Identify the Mechanism of Action of an Anti-Cancer Drug
Business Wire via Yahoo!:  Sep 16 2009 2:55PM Matching: nampt

Clinical Trials:

Clinical Trials Logo
Adipose Secretory Function in Patients Before & After Laparoscopic Surgery

NAMPT results (if any) from reagent suppliers

Google CSE Logo
Polyclonal Antibody to NAMPT/Visfatin
NAMPT is a 491 amino acid adipokine belonging to the NAPRTase family. It promotes angiogenesis via activation of the mitogen-activated ...
http://www.imgenex.com/tds/IMX-6096.pdf...

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Antibodies for Obesity Research
NAMPT(10135), mouse (predicted), human, rat, WB, pricing. L3160, Monoclonal Anti -Leptin antibody produced in mouse, LEP-13 (monoclonal), ascites fluid ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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Visfatin Antibody Bethyl Laboratories
Alternate Names, Visfatin, PBEF, PBEF1, PBEF-1, Pre-B cell Enhancing Factor 1, NAMPT, nicotinamide phosphoribosyltransferase. Type, Polyclonal ...
http://www.bethyl.com/product/A300-779A/Visfatin_Antibody/AA...

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monoclonal antibody template
PBEF, also called Nampt or visfatin, is a ubiquitous 52 kDa nicotinamide phosphoribosyltransferase. It is the rate-limiting component in the biosynthesis
of ...
http://www.rndsystems.com/pdf/MAB4044.pdf...

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PBEF (H-300) Antibody sc-67020
Mouse, Nampt, 59027, 12 A3, Q99KQ4, N/A. Ordering Information. Product Name, Catalog #, Unit, Price, Qty, Wish List. PBEF (H-300), sc-67020, 200 µg/ml, $259
...
http://www.scbt.com/datasheet-67020-pbef-h-300-antibody.html...

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Anti-Visfatin (C- terminal) (V9139) - Data Sheet
NAMPT), is a highly conserved protein involved in the regulation of cellular metabolism and energy ... nicotinamide phosphoribosyl transferase (NAMPT), ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...

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Visfatin C-terminal (Human) - EIA Kit - Extraction Free*
Plasma levels of PBEF/Nampt/visfatin are decreased in patients with liver cirrhosis. .... The circulating PBEF/NAMPT/visfatin level is associated with a
...
http://www.phoenixpeptide.com/catalog/product_info.php?produ...

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