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AKAP9
| Symbol: | AKAP9 | | Name(s): | A kinase (PRKA) anchor protein (yotiao) 9 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | AKAP350, AKAP450, CG-NAP, HYPERION, KIAA0803, MU-RMS-40.16A, PRKA9, YOTIAO | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18334708 |
Polymorphisms in AKAP9 M4631 were associated with increased risks for familial and nonfamilial breast cancer. The functional consequence of the AKAP9 M4631 polymorphism may involve the PKA pathway. |
| 18334708 |
Meta-analysis of gene-disease association. (HuGE Navigator) |
| 16741161 |
Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) |
| 18093912 |
genetic perturbations in AKAP9 disrupt its binding to KCNQ1 and have a role in long-QT syndrome |
| 11799244 |
included in a macromolecular complex with PKA and PP1 which is required for the regulation of hKCNQ1 by PKA-dependent phosphorylation |
| 12270714 |
findings support a model in which sub-cellular localization at the centrosome is mediated, at least in part, through the action of CG-NAP/AKAP450 |
| 15630448 |
AKAP9-BRAF fusion was preferentially found in radiation-induced papillary carcinomas developing after a short latency, whereas BRAF point mutations were absent in this group |
| 15670215 |
These results suggest that CG-NAP/D causes centrosome amplification by anchoring excess amount of cyclin E-cdk2 to centrosomes and, possibly, CG-NAP participates in centrosome duplication by recruiting cyclin E-cdk2 to centrosomes in normal cell cycle. |
| 16356588 |
AKAP350 has a role in the remodeling of the microtubule cytoskeleton. |
| 14982933 |
InsP(3)R1-PKA association is mediated by AKAP9; InsP(3)R1-AKAP9 binding promotes association of neuronal InsP(3)R1 with the NR1 NMDA receptor; and neuronal InsP(3)R1 associate with PP1 directly via carboxy-terminus and indirectly via AKAP9 | →View more information from publications. |
Recent Publications on AKAP9: |  |
Mechanisms of chromosomal rearrangements in solid tumors: The model of papillary thyroid carcinoma.
Thyroid cancer, and its most common type, papillary carcinoma, frequently... | 22nd September, 2009
| Department of Pathology and Laboratory Medicine, University of Pittsburgh,
| Mol Cell Endocrinol. 2009 Sep 18.
DOI Direct Link |
Ins(1,4,5)P3 receptor type 1 associates with AKAP9 (AKAP450 variant) and protein kinase A type IIbeta in the Golgi apparatus in cerebellar granule cells.
BACKGROUND INFORMATION: Interconnections between the Ca2+ and cAMP... | 9th September, 2009
| INSERM, U757, Orsay, France.
| Biol Cell. 2009 Jun 4;101(8):469-80.
DOI Direct Link |
Cep72 regulates the localization of key centrosomal proteins and proper bipolar spindle formation.
Microtubule-nucleation activity and structural integrity of the centrosome... | 6th August, 2009
| Division of Oncology, Department of Cancer Biology, The Institute of
| EMBO J. 2009 Jul 22;28(14):2066-76. Epub 2009 Jun 18.
DOI Direct Link |
Microtubule nucleation at the cis-side of the Golgi apparatus requires AKAP450 and GM130.
We report that microtubule (MT) nucleation at the Golgi apparatus requires... | 5th May, 2009
| Departamento de Senalizacion Celular, Centro Andaluz de Biologia Molecular
| EMBO J. 2009 Apr 22;28(8):1016-28. Epub 2009 Feb 26.
DOI Direct Link |
Microtubule-dependent association of AKAP350A and CCAR1 with RNA stress granules.
Recent investigations have highlighted the importance of subcellular... | 28th February, 2009
| Department of Surgery Vanderbilt University School of Medicine Nashville,
| Exp Cell Res. 2009 Feb 1;315(3):542-55. Epub 2008 Dec 3.
DOI Direct Link |
→View more research publications. |
AKAP9 results (if any) from reagent suppliers | 
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AKAP Antibody / AKAP Antibodies
AKAP 9 (G-20) Antibody, sc-34384, goat IgG, C-terminus (h), WB, IF, ... AKAP 9 ( L-18) Antibody, sc-34382, goat IgG, internal (h), WB, IF, ELISA, m, r, h ...
http://www.scbt.com/table-akap.html...
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Abgent - Phosphorylation Antibodies - Phosphorylation
AT1089a, AKAP8 monoclonal antibody (M01), ELISA,IF,IHC-P,S-ELISA,WB-Ce,WB-Re, H. AT1090a, AKAP9 monoclonal antibody (M01), ELISA,S-ELISA,WB-Re, H ...
http://www.abgent.com/products/category/protein_modification...
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AKAP 9 siRNA (m) sc-45365
Click here for details. contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: AKAP 9 (m)-PR: sc-45365-PR, 20 µl ...
http://www.scbt.com/datasheet-45365-akap-9-sirna-m.html...
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All Cell Type Markers | Abcam
AKAP9 antibody. WB, ELISA. Rabbit polyclonal. Reacts with: ... AKAP9 antibody [ 17G10]. IP, WB, ICC/IF. Mouse monoclonal. Reacts with: Hu. Predicted: ...
http://www.abcam.com/index.html?c=586...
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AKAP Antibody / AKAP Antibodies
AKAP 9 (G-20) 抗体, sc-34384, goat IgG, C-terminus (h), WB, IF, ELISA, m, r, h ... AKAP 9 (L-18) 抗体, sc-34382, goat IgG, internal (h), WB, IF, ELISA ...
http://www.scbt.com/zh/table-akap.html...
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AZ Bethyl Laboratories - Welcome Bethyl Laboratories
AKAP8L/HA95 · AKAP9/CG-NAP · AKAP95/AKAP8 · AKAP-Lbc/AKAP13 · AKT1 · AKT2 · AktS1/PRAS40 · Albumin · Alligator IgG-heavy and light chain · Alligator Whole
...
http://www.bethyl.com/category/PCA_A-Z/Antibody/AAAAAAAABAAG...
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Abcam antibodies and reagents product map
AKAP9 antibodies (3) · Alpha Fodrin antibodies (1) · Apoptosis repressor with CARD antibodies (1) · Arg 3.1 antibodies (5) · Arg 3.1 proteins and peptides ...
http://www.abcam.com/index.html?cl=251&pageconfig=productmap...
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