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G3BP1


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Symbol:G3BP1
Name(s):GTPase activating protein (SH3 domain) binding protein 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:G3BP, HDH-VIII, MGC111040
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17696235 The expression of G3BP and RhoC protein is closely related to the lymph node metastasis and survival in esophageal squamous carcinoma (ESC) patients. G3BP and RhoC proteins can be considered as predictors of prognosis in ESC patients.
15602692 G3BPs are scaffolding proteins linking signal transduction to RNA metabolism (review)
15471883 involvement of cellular protein G3BP in transcription of intermediate stage genes may regulate the transition between early and late phases of vaccinia virus replication
16996479 Hepatitis C virus viral gene and proteins may regulate the presence of host cellular proteins in detergent resistant membrane
17210633 Caprin-1/G3BP-1 complex is likely to regulate the transport and translation of mRNAs of proteins involved with synaptic plasticity in neurons
17297477 Both G3BP1 and G3BP2 isoforms may act as negative regulators of tumor suppressor protein p53.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDRasGAPRas-GTPase-activating protein SH3-domain-binding protein--Pubmed
HPRDRAS p21 protein activator 1 isoform 1Ras-GTPase-activating protein SH3-domain-binding protein--Pubmed
HPRDubiquitin specific protease 10Ras-GTPase-activating protein SH3-domain-binding protein--Pubmed
HPRDubiquitin specific protease 10Ras-GTPase-activating protein SH3-domain-binding protein--Pubmed

Recent Publications on G3BP1:

Pubmed Logo
Different types of nsP3-containing protein complexes in Sindbis virus-infected cells.
Alphaviruses represent a serious public health threat and cause a wide...
15th October, 2008
Department of Microbiology and Immunology, University of Texas Medical J Virol. 2008 Oct;82(20):10088-101. Epub 2008 Aug 6.
DOI Direct Link
Modulation of p53 and MDM2 activity by novel interaction with Ras-GAP binding proteins (G3BP).
Inactivation of the p53 tumor suppressor pathway is a critical step in...
19th August, 2007
Department of Genetics and Complex Diseases, Harvard School of Public Oncogene. 2007 Jun 21;26(29):4209-15. Epub 2007 Feb 5.
DOI Direct Link
Dynamic association with polysomes during P19 neuronal differentiation and an untranslated-region-dependent translation regulation of the tau mRNA by the tau mRNA-associated proteins IMP1, HuD, and G3BP1.
Regulation of mRNA translation is a key step in mediating neuronal...
22nd March, 2007
Department of Neurobiology, Weizmann Institute of Science, Rehovot, J Neurosci Res. 2007 Jan;85(1):173-83.
DOI Direct Link
Subproteomic study of hepatitis C virus replicon reveals Ras-GTPase-activating protein binding protein 1 as potential HCV RC component.
Hepatitis C virus (HCV) RNA synthesis takes place on a detergent resistant...
9th December, 2006
Key Laboratory of Medical Molecular Virology, Institute of Medical Biochem Biophys Res Commun. 2006 Nov 10;350(1):174-8. Epub 2006 Sep 18.
DOI Direct Link
Subproteomic analysis of the cellular proteins associated with the 3' untranslated region of the hepatitis C virus genome in human liver cells.
The 3' untranslated region (UTR) of the hepatitis C virus (HCV) is...
14th September, 2006
Key Laboratory of Medical Molecular Virology, Shanghai Medical College, Biochem Biophys Res Commun. 2006 Sep 1;347(3):683-91. Epub 2006 Jul 5.
DOI Direct Link

View more research publications.

G3BP1 results (if any) from reagent suppliers

Google CSE Logo
p-G3BP1 (Ser 232) Antibody sc-101684
Western blot analysis of phosphorylated G3BP1 expression in 293 whole cell lysate ... Blots were probed with p-G3BP1 (Ser 232): sc-101684 preincubated with
...
http://www.scbt.com/datasheet-101684-p-g3bp1-ser-232-antibod...

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Antibodies to Oxidative Stress Proteins
G3BP1(10146), human, mouse (predicted), rat (predicted), IF (i), WB, pricing. HPA023087, Anti-GLRX2 antibody produced in rabbit New, (polyclonal) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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G3BP1 (TT-Y) Antibody sc-81940
G3BP1 (TT-Y): sc-81940. Immunofluorescence staining of paraformaldehyde-fixed HeLa cells showing nuclear and cytoplasmic localization. ...
http://www.scbt.com/datasheet-81940-g3bp1-tt-y-antibody.html...

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GTPase Activity Product Focus Bethyl Laboratories
G3BP1 · A302-033A · A302-034A · A302-033A · A302-034A · G3BP2 · A302-040A · A302 -040A · A302-041A. Applications. Target, Western Blot, IHC ...
http://www.bethyl.com/content/GTPase_Focus...

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G3BP1 (C-14) Antibody sc-70283
G3BP1 shRNA (h) Lentiviral Particles, sc-75076-V, 200 µl, $595. G3BP1 shRNA (m) Lentiviral Particles, sc-75077-V, 200 µl ...
http://www.scbt.com/datasheet-70283-g3bp1-c-14-antibody.html...

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Recombinant Proteins - Protein and Antibody Solutions Provider ...
G3BP; G3BP1; G3BP; HDH-VIII; MGC111040 - EC 3.6.1.-; ATP-dependent DNA helicase VIII; GAP SH3-domain-binding protein 1; G3BP-1; HDH-VIII; ...
http://www.genwaybio.com/all_recombinant_proteins.php?fl=R...

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G3BP Antibody / G3BP Antibodies
G3BP1 (C-14) Antibody, sc-70283, goat IgG, C-terminal (h), WB, IF, ELISA ... p- G3BP1 (Ser 232) Antibody, sc-101684, rabbit IgG, Ser 232 (h), WB, IP, IF, ...
http://www.scbt.com/table-g3bp.html...

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