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EBI3


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Gene DB Home
Symbol:EBI3
Name(s):Epstein-Barr virus induced gene 3
Type:protein-coding
Organism:Homo sapiens
Synonyms:-
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
15170639 results suggest that increased numbers of Epstein-Barr virus-infected cells in areas of active inflammatory bowel disease are secondary to influx or local proliferation of inflammatory cells & do not contribute significantly to local production of EBI3
12121660 a new heterodimeric cytokine that consists of EBI3, an IL-12p40-related protein, and p28, a newly discovered IL-12p35-related polypeptide (IL-27)

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDcalnexin precursorEpstein-Barr virus induced gene 3 precursor--Pubmed
HPRDinterleukin 12AEpstein-Barr virus induced gene 3 precursor--Pubmed
HPRDHomo sapiens encoding human GOS28/P28 protein., and translated productsEpstein-Barr virus induced gene 3 precursor--Pubmed

Recent Publications on EBI3:

Pubmed Logo
Molecular cloning, expression and characterization of an interleukin 27 p28 homolog in pig (Sus scrofa).
IL-27 is the newest member of the IL-12 cytokine family and plays an...
20th October, 2009
Institute for Viral Hepatitis, Key Laboratory of Molecular Biology for Vet Immunol Immunopathol. 2009 Aug 15;130(3-4):262-7. Epub 2009 Feb 14.
DOI Direct Link
The secreted form of p28 subunit of interleukin (IL)-27 inhibits biological functions of IL-27 and suppresses anti-allogeneic immune responses.
Interleukin-27 (IL-27) is a new IL-12-related heterodimeric cytokine...
25th September, 2009
Division of Pathology, Chiba Cancer Centre Research Institute, Nitona, Immunology. 2009 Sep;128(1 Suppl):e816-25. Epub 2009 Mar 23.
DOI Direct Link
Production of both IL-27 and IFN-gamma after the treatment with a ligand for invariant NK T cells is responsible for the suppression of Th2 response and allergic inflammation in a mouse experimental asthma model.
Using an allergen-induced airway inflammation model, we show that an...
21st August, 2009
RIKEN Research Center for Allergy and Immunology, Suehiro, Tsurumi, J Immunol. 2009 Jul 1;183(1):254-60.
DOI Direct Link
Interleukin-27 polymorphisms are associated with inflammatory bowel diseases in a Korean population.
BACKGROUND AND AIMS: The cytokine interleukin (IL)-27 is composed of two...
19th August, 2009
Genome Research Center for Immune Disorders, Wonkwang University School of J Gastroenterol Hepatol. 2009 Oct;24(10):1692-6. Epub 2009 Aug 3.
DOI Direct Link
Epstein-barr virus-induced gene-3 is expressed in human atheroma plaques.
Atherosclerosis is characterized by a complex immune response in the...
16th July, 2009
Institute of Physiological Chemistry, Ulm University, Ulm, Germany. Am J Pathol. 2009 Jul;175(1):440-7.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7608256 Methods to increase transgene expression from bacterial-based delivery systems by co-expressing suppressors of the eukaryotic type I interferon response
7115712 Cytokine polypeptides
6936417 Gene expression in bladder tumors
6800460 Mammalian cytokine complexes
6607879 Compositions for the detection of blood cell and immunological response gene expression

View more patents.

EBI3 results (if any) from reagent suppliers

Google CSE Logo
Ebi3 Antibody / Ebi3 Antibodies
Ebi3 Antibody / Ebi3 Antibodies. ... Ebi3 specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-ebi3.html...

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EBI3 Antibody (IN) Epstein-Barr virus induced 3 precursor
EBI3 antibody can be used for the detection of EBI3 by Western blot at 2 – 4 μg/ ml.,
http://www.prosci-inc.com/shop/catalog1/EBI3-Antibody-p-6812...

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EBI3 monoclonal antibody (M01)
EBI3 monoclonal antibody (M01) Cell Function, EBI3 monoclonal antibody (M01)
http://www.abgent.com/products/catalog_no/AT1847a...

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Ebi3 (M-75) Antibody sc-32869
rabbit polyclonal IgG, 200 µg/ml; epitope corresponding to amino acids 154-228 mapping at the C-terminus of Ebi3 of mouse origin; recommended for detection ...
http://www.scbt.com/datasheet-32869-ebi3-m-75-antibody.html...

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mouse IL-27 antibody, Cytokine Kits conjugate
Contents: Mouse IL-27 (p28/EBI3) ELISA Ready-SET-Go!TM .... IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation
of naïve ...
http://www.ebioscience.com/ebioscience/specs/antibody_88/88-...

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Ebi3 (E-20) Antibody sc-26798
goat polyclonal IgG, 200µg/ml; epitope mapping within an internal region of Ebi3 of human origin; recommended for detection of Ebi3 of human origin by WB, ...
http://www.scbt.com/datasheet-26798-ebi3-e-20-antibody.html...

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Affinity Purified anti-mouse EBI3 (IL-27 subunit)
1 Jul 2009 ... eBioscience technical data sheet for product 14-7273 Affinity Purified anti- mouse EBI3 (IL-27 subunit) DNT27 antibody.
http://www.ebioscience.com/ebioscience/specs/antibody_14/14-...

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