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P2RY5


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Symbol:P2RY5
Name(s):purinergic receptor P2Y, G-protein coupled, 5
Type:protein-coding
Organism:Homo sapiens
Synonyms:MGC120358, P2Y5
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18297070 Autosomal recessive form of hypotrichosis simplex mapped to chromosome 13q14.11-13q21.33, and identified homozygous truncating mutations in P2RY5.
18297072 Disruption of P2RY5, an orphan G protein-coupled receptor, underlies autosomal recessive woolly hair.
9240460 Expression of turkey (Meleagris gallopavo) 6H1/p2y5 receptor in human astrocytoma cells and measurement of second mesenger levels indicate it is not a member of the P2Y receptor family.

Recent Publications on P2RY5:

Pubmed Logo
Novel mutations in the P2RY5 gene in one Turkish and two Indian patients presenting with hypotrichosis and woolly hair.
Hypotrichosis simplex comprises a group of non-syndromic human alopecias....
23rd October, 2009
Institute of Human Genetics, University of Bonn, 53111 Bonn, Germany. Arch Dermatol Res. 2009 Sep;301(8):621-4. Epub 2009 Jun 16.
DOI Direct Link
New bioinformatics approach to analyze gene expressions and signaling pathways reveals unique purine gene dysregulation profiles that distinguish between CD and UC.
BACKGROUND: Expression of purine genes is modulated by inflammation or...
2nd September, 2009
Department of Bioinformatics, Ohio State University, Columbus, Ohio 43210, Inflamm Bowel Dis. 2009 Jul;15(7):971-84.
DOI Direct Link
Autosomal recessive woolly hair with hypotrichosis caused by a novel homozygous mutation in the P2RY5 gene.
During the last decade, several causative genes for hereditary hair...
18th August, 2009
Department of Dermatology, Columbia University, New York, NY 10032, USA Exp Dermatol. 2009 Mar;18(3):218-21. Epub 2008 Sep 18.
DOI Direct Link
Founder mutations in the lipase h gene in families with autosomal recessive woolly hair/hypotrichosis.
Autosomal-recessive woolly hair (ARWH)/hypotrichosis is a hereditary hair...
1st August, 2009
Department of Dermatology, Columbia University, New York, New York, USA. J Invest Dermatol. 2009 Aug;129(8):1927-34. Epub 2009 Mar 5.
DOI Direct Link
The effect of inbreeding on the distribution of compound heterozygotes: a lesson from Lipase H mutations in autosomal recessive woolly hair/hypotrichosis.
Autozygosity mapping in consanguineous families has proven to be a...
25th July, 2009
Department of Dermatology, School of Public Health, Columbia University, Hum Hered. 2009;68(2):117-30. Epub 2009 Apr 9.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7598080 Diagnostic assay for source of inflammation
7595387 Modified polynucleotides for reducing off-target effects in RNA interference

P2RY5 results (if any) from reagent suppliers

Google CSE Logo
P2RY5 antibodies: Signal Transduction > Signaling Pathway > G ...
P2RY5 antibodies. ... Image Abreview Publication. ab85894 · P2RY5 antibody. IHC- P, WB, IHC-Fr. Rabbit polyclonal. Reacts with: Hu, Ms, Rat ...
http://www.abcam.com/index.html?t=287166&pt=1&c=2191&ei=&mu=...

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P2Y5 (C-20) Antibody sc-15214
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, P2RY5, 10161, 13q14.2, NM_005767 ...
http://www.scbt.com/datasheet-15214-p2y5-c-20-antibody.html...

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U4125 Uridine 5′-diphosphate sodium salt from Saccharomyces ...
LPAR4(2846), LTB4R(1241), P2RY1(5028), P2RY10(27334), P2RY11(5032), P2RY12(64805 ), P2RY13(53829), P2RY14(9934), P2RY2(5029), P2RY4(5030), P2RY5(10161), ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...

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P2Y Antibody / P2Y Antibodies
製品名, カタログ番号, アイソタイプ, エピトープ, アプリケーション, 動物種. P2Y1 ( A-15) 抗体, sc-15204, goat IgG, internal (h), WB, IF, ELISA, m, r, h, ...
http://www.scbt.com/ja/table-p2y.html...

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Abcam antibodies and reagents product map
... Orexin Receptor 1 and 2 antibodies (1) · Orexin Receptor 2 antibodies (7) · Oxytocin Receptor antibodies (1) · P2RY5 antibodies (1) · P2Y1 antibodies (3 ...
http://www.abcam.com/index.html?cl=2105&pageconfig=productma...

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P2Y5 siRNA (m) sc-45384
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, P2ry5, 67168, 14 D3, Q8BMC0 ...
http://www.scbt.com/ko/datasheet-45384-p2y5-sirna-m.html...

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P2Y5 (H-60) Antibody sc-20126
... Numero de Accesion de Isoforma (ARNm), Numero de Accesion de la Proteina, Número de pedido: Humano, P2RY5, 10161, 13q14.2, NM_005767 · P43657 ...
http://www.scbt.com/es/datasheet-20126-p2y5-h-60-antibody.ht...

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