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CDKN1A
| Symbol: | CDKN1A | | Name(s): | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17941827 |
that Rac1 is an essential player for mediating the induction of cyclin D1 and p21(Cip1) by HRG in breast cancer cells |
| 18205772 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18226366 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18251939 |
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) |
| 18281541 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18361427 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18025091 |
the ability of Tbx2 to repress the p21 gene is enhanced in response to a stress-induced senescence pathway, which leads to a better understanding of the regulation of the anti-senescence function of Tbx2. |
| 18166158 |
These results imply that HIF-1alpha functions as an up-stream player in the p21-mediated growth arrest of keratinocytes. |
| 18230337 |
Our results indicate that nicotinamide treatment attenuates p21WAF1 expression through Sp1 downregulation, and suggest a possible involvement of nicotinamide metabolism in cellular gene expression. |
| 17008550 |
Observational study of gene-disease association. (HuGE Navigator) | →View more information from publications. |
Recent Publications on CDKN1A: |  |
Cordycepin causes p21WAF1-mediated G2/M cell-cycle arrest by regulating c-Jun N-terminal kinase activation in human bladder cancer cells.
Cordycepin (3'-deoxyadenosine), a bioactive compound of Cordyceps... | 31st October, 2009
| Department of Food and Biotechnology, Chungju National University,
| Arch Biochem Biophys. 2009 Oct 15;490(2):103-9. Epub 2009 Sep 5.
DOI Direct Link |
Overexpression of FOXG1 contributes to TGF-beta resistance through inhibition of p21WAF1/CIP1 expression in ovarian cancer.
BACKGROUND: Loss of growth inhibitory response to transforming growth... | 29th October, 2009
| Department of Obstetrics and Gynaecology, LKS Faculty of Medicine,
| Br J Cancer. 2009 Oct 20;101(8):1433-43. Epub 2009 Sep 15.
DOI Direct Link |
Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis.
BACKGROUND: Dysregulation of the cell cycle is a hallmark of many cancers... | 29th October, 2009
| Department of Laboratory Medicine and Pathology, Mayo Clinic College of
| Br J Cancer. 2009 Oct 20;101(8):1461-8. Epub 2009 Sep 8.
DOI Direct Link |
Scl regulates the quiescence and the long-term competence of hematopoietic stem cells.
The majority of long term reconstituting hematopoietic stem cells (LT-HSC)... | 24th October, 2009
| Institute of Research in Immunology and Cancer (IRIC), Montreal, Canada;
| Blood. 2009 Oct 22.
DOI Direct Link |
Polyploidy impairs human aortic endothelial cell function and is prevented by nicotinamide phosphoribosyltransferase.
Polyploid endothelial cells are found in aged and atherosclerotic... | 23rd October, 2009
| 1The University of Western Ontario.
| Am J Physiol Cell Physiol. 2009 Oct 21.
DOI Direct Link |
→View more research publications. |
CDKN1A results (if any) from reagent suppliers | 
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CDKN1A Antibody
Specific antibody for the gene product of CDKN1A, the protein Cyclin-dependent kinase inhibitor 1A, p21. Validated for specificity by gene-silencing with ...
http://www.piercenet.com/products/browse.cfm?fldID=7A45C59F-...
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CDKN1A Antibody Wild type p53 activated fragment-1 (p21)
CDKN1A antibody can be stored at 4C for short term (weeks) and -20C for long term.,
http://www.prosci-inc.com/shop/catalog1/CDKN1A-Antibody-p-16...
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p21 (CDKN1A) Antibody (C-term)
p21 (CDKN1A) Antibody (C-term) Cell Function, p21 (CDKN1A) Antibody (C-term) Apoptosis, p21 (CDKN1A) Antibody (C-term) Cell Function, p21 (CDKN1A) Antibody
...
http://www.abgent.com/products/catalog_no/AP7527b...
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Immunohistochemistry : p21/CIP1/CDKN1A - R&D Systems
IHC Images. Immunohistochemistry : p21/CIP1/CDKN1A. p21 in Human Breast Cancer. Detection of p21 in paraffin-embedded human breast cancer tissue sections ...
http://www.rndsystems.com/ihc_molecule_images.aspx?m=1944...
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CDKN1A interacting zinc finger protein 1 antibodies: Cell Biology ...
CDKN1A interacting zinc finger protein 1 antibodies.
http://www.abcam.com/index.html?t=206001&pt=1&c=268&ei=&mu=r...
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BCCIP Antibody (Center))
Western blot analysis of anti-BRCA2 and CDKN1A Interacting Protein Pab (Cat. # AP1923a) in A375 cell line lysate. BRCA2 and CDKN1A Interacting Protein(arrow)
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http://www.abgent.com/products/catalog_no/AP1923a...
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Search for Products - R&D Systems
p21/CIP1/CDKN1A, Human p21/CIP1/CDKN1A Affinity Purified Polyclonal Ab, Goat IgG ... p21/CIP1/CDKN1A, Human Total p21/CIP1/CDKN1A DuoSet IC Economy Pack, ...
http://www.rndsystems.com/product_results.aspx?m=1944&c=0...
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