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ADAR


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Symbol:ADAR
Name(s):adenosine deaminase, RNA-specific
Type:protein-coding
Organism:Homo sapiens
Synonyms:ADAR1, DRADA, DSH, DSRAD, G1P1, IFI-4, IFI4, K88dsRBP, p136
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
12447867 Observational study of gene-environment interaction. (HuGE Navigator)
16886895 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17569068 G to A mutation at the position 3,125 in exon 12 of the DSRAD gene induces a R1042H change in the putative deaminase domain of DSRAD. This, among other DSRAD mutations, is characteristic to dyschromatosis symmetrica hereditaria
17020943 ADAR1-L induces mutations in the viral RNA which leads to a loss of viral protein function and reduced viral infectivity, and contributes to the innate antiviral immune response.
11907222 overexpression inhibits HDV RNA replication and compromises virus viabiltiy
16475990 induction of ADAR1-L may at least partially cause the antiviral effect of IFN-alpha in natural immune response to HDV as well as in case of therapeutic administration of IFN
16133458 Identification of a deletion mutation in the ADAR gene of a Chinese family with Dyschromatosis symmetrica hereditaria is reported.
15146470 data add new variants to the repertoire of ADAR mutations in Dyschromatosis symmetrica hereditaria
15342791 Atomic force microscopy imaging of the Zalpha domain of ADAR1 complexed with supercoiled plasmid Z-DNA.
15102079 This is the first report on DSRAD as the causative gene of dyschromatosis symmetrica hereditaria in the Chinese population.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDadenosine deaminase, RNA-specific isoform ADAR-aexportin 1--Pubmed
HPRDadenosine deaminase, RNA-specific isoform ADAR-aexportin 1--Pubmed

Recent Publications on ADAR:

Pubmed Logo
[Idiopathic right-sided endocarditis: an uncommon manifestation of pulmonary cavitations]
Approximately 5-10% of endocarditis cases are right-sided. CLinicaL...
26th September, 2009
Department of Internal Medicine A, Internal Medicine Division, Hadassah Harefuah. 2009 Apr;148(4):233-4, 277.
Adenosine deamination in human transcripts generates novel microRNA binding sites.
Animals regulate gene expression at multiple levels, contributing to the...
25th September, 2009
Department of Internal Medicine, University of Iowa, Iowa City, IA, 52242, Hum Mol Genet. 2009 Sep 23.
DOI Direct Link
Adenosine-to-inosine genetic recoding is required in the adult stage nervous system for coordinated behavior in Drosophila.
Adenosine deaminases acting on RNA (ADARs) catalyze the deamination of...
18th September, 2009
Department of Molecular Biology, Cell Biology and Biochemistry, Brown J Biol Chem. 2009 Nov 6;284(45):31391-400. Epub 2009 Sep 15.
DOI Direct Link
Enhancing non-coding RNA information content with ADAR editing.
The depth and complexity of the non-coding transcriptome in nervous system...
16th September, 2009
Department of Molecular Biology, Cell Biology, and Biochemistry, Brown Neurosci Lett. 2009 Dec 4;466(2):89-98. Epub 2009 Sep 12.
DOI Direct Link
Approach to estimating participant pollutant exposures in the Multi-Ethnic Study of Atherosclerosis and Air Pollution (MESA Air).
Most published epidemiology studies of long-term air pollution health...
12th September, 2009
Department of Environmental and Occupational Health Sciences, University Environ Sci Technol. 2009 Jul 1;43(13):4687-93.

View more research publications.

Clinical Trials:

Clinical Trials Logo
Prospective Study for Safety and Efficacy of SpaceGuard™ in Rotator Cuff Tear Subjects

Patents:

Patents logo
US Patent No.Title
7545211 Predistortion linearization device with adjustable amplitude and shape
7568168 Method and apparatus for capturing and rendering text annotations for non-modifiable electronic content
7569687 Processes for the synthesis of rocuronium bromide
7571186 Locating potentially identical objects across multiple computers based on stochastic partitioning of workload
7571327 Exclusive encryption

View more patents.

ADAR results (if any) from reagent suppliers

Google CSE Logo
ADAR Antibody / ADAR Antibodies
ADAR Antibody / ADAR Antibodies. ... ADAR specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-adar.html...

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Abgent - Stem Cell
AP7102a, Activin A Receptor Type IC (ACVR1C) Antibody (N-term A48), WB, IHC, E, H. AP1493a, Adenosine Deaminase (ADAR) Antibody (N-term), WB, E, H ...
http://www.abgent.com/products/category/stem_cell...

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ADAR Antibody / ADAR Antibodies
ADAR Antibody / ADAR Antibodies. ... ADAR specific siRNA, sHRNA Plasmid과 shRNA Lentiviral Particles gene silencers 도 제공합니다. ...
http://www.scbt.com/ko/table-adar.html...

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ADAT1 antibody (ab50994) | Abcam
ADAT1 is a member of the ADAR (Adenosine Deaminase Acting on RNA) family. Using site-specific adenosine modification, these proteins participate in th...
http://www.abcam.com/ADAT1-antibody-ab50994.html...

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ADAR1 (15.8.6) Antibody sc-73408
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, ADAR, 103, 1q21.3, P55265 ...
http://www.scbt.com/datasheet-73408-adar1-15-8-6-antibody.ht...

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Anti-Procollagen C-Proteinase Enhancer Protein-2 antibody produced ...
Kessler, E., and Adar, R., Eur. J. Biochem., 186,. 156-121 (1989). 3. Takahara, K., et al., J. Biol. Chem., 269, 26280-. 26285 (1994). kaa 12/02 ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...

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ADAR1 (C-16) Antibody sc-10002
Additional ADAR Antibodies . ... Human, ADAR, 103, 1q21.3, NM_001025107, NM_001111, NM_015840, NM_015841 · P55265 · 146920. Mouse, Adar, 56417, 3 F1,
Q99MU3 ...
http://www.scbt.com/datasheet-10002-adar1-c-16-antibody.html...

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