Friday November 27 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

ABCA7


Suggest Content
Advertise Here
Gene DB Home
Symbol:ABCA7
Name(s):ATP-binding cassette, sub-family A (ABC1), member 7
Type:protein-coding
Organism:Homo sapiens
Synonyms:ABCA-SSN, ABCX, FLJ40025
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
15593299 Observational study of gene-disease association. (HuGE Navigator)
12917409 ABCA7 has the ability to bind apolipoproteins and promote efflux of cellular phospholipids without cholesterol, and has a possible role of ABCA7 in cellular phospholipid metabolism in peripheral tissues
15930518 the ABCA7-mediated reaction generated mostly small cholesterol-poor particles; ABCA7 produces this HDL subfraction only as a very minor component.
14592415 Alternative splicing could be involved in the post-transcriptional regulation of the expression and function of human ABCA7
12925201 Overexpression of ABCA7 in HeLa cells resulted in increased expression of intracellular and cell surface ceramide and elevated intracellular phosphatidylserine levels.
16908670 These studies reveal a major role of ABCA7 and not -A1 in the clearance of apoptotic cells and therefore suggest that ABCA7 is an authentic orthologue of CED-7.
14570867 ABCA7 compensates the function of ABCA1 for release of cell cholesterol in a certain condition(s).

Recent Publications on ABCA7:

Pubmed Logo
Differential expression and localization of lipid transporters in the bovine mammary gland during the pregnancy-lactation cycle.
The transport of lipids across mammary gland epithelial cells (MEC)...
20th October, 2009
Institute of Biochemistry and Molecular Medicine, University of Bern, J Dairy Sci. 2009 Aug;92(8):3744-56.
DOI Direct Link
Apoptotic engulfment pathway and schizophrenia.
BACKGROUND: Apoptosis has been speculated to be involved in schizophrenia....
2nd September, 2009
Department of Psychiatry and Virginia Institute for Psychiatric and PLoS One. 2009 Sep 1;4(9):e6875.
DOI Direct Link
Defective CFTR increases synthesis and mass of sphingolipids that modulate membrane composition and lipid signaling.
Cystic fibrosis (CF) is caused by mutations in the CF transmembrane...
13th August, 2009
Department of Pathology, Columbia University, New York, NY 10032, USA. J Lipid Res. 2009 Jun;50(6):1101-8. Epub 2009 Jan 14.
DOI Direct Link
Characterization of the ATP-binding cassette transporter gene expression profile in Y79: a retinoblastoma cell line.
Chemotherapy failure was reported in treatment of retinoblastoma...
7th March, 2009
Institut fur Laboratoriums- und Transfusionsmedizin, Herz- und Mol Cell Biochem. 2009 Aug;328(1-2):85-92. Epub 2009 Mar 6.
DOI Direct Link
Differential expression of ABC transporters and their regulatory genes during lactation and dry period in bovine mammary tissue.
ATP-binding cassette (ABC) transporters play a pivotal role in human...
1st January, 2009
Physiology Weihenstephan, Technical University Munich, 85354 Freising, J Dairy Res. 2008 Nov;75(4):406-14. Epub 2008 Aug 14.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7547687 Therapeutic treatment methods
7504225 Reagents and methods for use in cancer diagnosis, classification and therapy
7482334 Therapeutic treatment methods

ABCA7 results (if any) from reagent suppliers

Google CSE Logo
ABCA7 antibody [7A1-144] (ab48265) | Abcam
Rat monoclonal [7A1-144] to ABCA7. ATP-binding cassette (ABC)1 transporters are a superfamily of highly conserved membrane proteins that transport a wide ...
http://www.abcam.com/ABCA7-antibody-7A1-144-ab48265.html...

Thumbshot
Anti-ABCA7 Monoclonal Antibody
Monoclonal Antibody against ABCA7 for use in Flow Cytometry, Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...

Thumbshot
ABCA7 antibody [4A7-144.1] (Phycoerythrin) (ab80047) | Abcam
Rat monoclonal [4A7-144.1] to ABCA7 (Phycoerythrin). ATP-binding cassette (ABC)1 transporters are a superfamily of highly conserved membrane proteins that ...
http://www.abcam.com/ABCA7-antibody-4A7-144-1-Phycoerythrin-...

Thumbshot
ABCA7 (K-15) Antibody sc-34556
ABCA7 siRNA shRNA (h) Lentiviral Particles, sc-45431-V, 200 µl ... Western blot analysis of ABCA7 expression in rat thymus tissue extract. Download ...
http://www.scbt.com/datasheet-34556-abca7-k-15-antibody.html...

Thumbshot
ABCA7 antibodies: Signal Transduction > Metabolism > Plasma ...
ABCA7 antibodies. ... Image Abreview Publication. ab80047 · ABCA7 antibody [4A7- 144.1] (Phycoerythrin). Flow Cyt. Rat monoclonal. Phycoerythrin conjugated ...
http://www.abcam.com/index.html?t=152871&pt=1&c=2250&ei=&mu=...

Thumbshot
ABC Antibody / ABC Antibodies
ABCA7 (H-138) Antibody, sc-50524, rabbit IgG, 1871-2008 (h), WB, IP, IF, ELISA, human. ABCA7 (K-15) Antibody, sc-34556, goat IgG, C-terminus (h), WB, IP, ...
http://www.scbt.com/table-abc.html...

Thumbshot
Primary antibodies | Abcam
ABCA7 antibody [4A7-144.1] (Phycoerythrin). Flow Cyt. Rat monoclonal. Phycoerythrin conjugated ... ABCA7 antibody [7A1-144]. Flow Cyt, WB ...
http://www.abcam.com/index.html?pageconfig=catalog_byproduct...

Thumbshot

Search Bioportfolio and other Life Science Sites for ABCA7, or search for ABCA7 on BioPortfolio's antibody search engine.
This page has been viewed 107 times
Recent Search Terms used to find this page:
abca7 wb human | abca8 antibody | .


Resources from the NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.