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YAP1
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18280240 |
YAP1 phosphorylation by c-Abl is a critical step in selective activation of proaptotic genes in response to DNA damage. |
| 17823615 |
YAP identified as a novel and critical downstream effector of c-Jun-mediated apoptosis following cisplatin treatment |
| 17980593 |
findings report that YAP1 increases organ size and causes aberrant tissue expansion |
| 17889654 |
Delineate a mammalian Hippo signaling pathway that culminates in the phosphorylation of YAP, the mammalian homolog of Yki. Is a potent regulator of organ size, and its dysregulation leads to tumorigenesis. |
| 11743730 |
NMR structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries reveal a minimal binding epitope |
| 16596258 |
Results suggested that YAP65 plays a role in the normal and diseased pancreas. |
| 15800888 |
the minimum binding domain is larger than the latter two strands of the WW domain beta-sheet |
| 17502622 |
Proline-rich Gla protein 2 may be involved in a signal transduction pathway, the impairment of which may be an unintended consequence of warfarin therapy |
| 15096513 |
Yap binds to HNRNPU and regulates its co-activation of Bax transcription |
| 16772533 |
WBP-2 and YAP are coactivators for estrogen and progesterone receptor transactivation pathways. | →View more information from publications. |
Interacting gene products |
| Interaction Type |
Gene 1 |
Gene 2 |
Interaction description |
Complex |
Publication Link |
| HPRD | Runt related transcription factor 2 | Yes-associated protein 1, 65 kD | - | - | Pubmed |
| HPRD | runt-related transcription factor 1 isoform AML1c | Yes-associated protein 1, 65 kD | - | - | Pubmed |
| HPRD | v-erb-a erythroblastic leukemia viral oncogene homolog 4 isoform JM-a/CVT-1 precursor | Yes-associated protein 1, 65 kD | - | - | Pubmed |
| HPRD | v-erb-a erythroblastic leukemia viral oncogene homolog 4 isoform JM-a/CVT-1 precursor | Yes-associated protein 1, 65 kD | - | - | Pubmed |
| HPRD | SMAD family member 7 | Yes-associated protein 1, 65 kD | - | - | Pubmed |
| HPRD | SMAD family member 7 | Yes-associated protein 1, 65 kD | - | - | Pubmed |
| BIND | nuclear factor, 45kDa | Yes-associated protein 1, 65 kD | p45 interacts with hYAP. | - | Pubmed |
| HPRD | Tea domain family member 1 | Yes-associated protein 1, 65 kD | - | - | Pubmed |
| HPRD | TEA domain family member 1 | Yes associated protein | - | - | Pubmed |
| HPRD | Transcription factor RTEF1 | Yes-associated protein 1, 65 kD | - | - | Pubmed |
Recent Publications on YAP1: |  |
Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene.
Hippo-Lats-Yorkie signaling regulates tissue overgrowth and tumorigenesis... | 3rd November, 2009
| Department of Molecular Biology, Massachusetts General Hospital, Boston,
| Cancer Cell. 2009 Nov 6;16(5):425-38.
DOI Direct Link |
Identification of Saccharomyces cerevisiae Genes Involved in the Resistance to Phenolic Fermentation Inhibitors.
Saccharomyces cerevisiae was exposed to inhibitory concentrations of the... | 23rd October, 2009
| Applied Microbiology, Lund University, SE-221 00, Lund, Sweden.
| Appl Biochem Biotechnol. 2009 Oct 22.
DOI Direct Link |
The YAP1 homolog-mediated oxidative stress tolerance is crucial for pathogenicity of the necrotrophic fungus Alternaria alternata in citrus.
Citrus brown spot disease is caused by the necrotrophic fungus Alternaria... | 10th October, 2009
| Citrus Research and Education Center, and Department of Plant Pathology,
| Mol Plant Microbe Interact. 2009 Aug;22(8):942-52.
DOI Direct Link |
Activation of the oxidative stress regulator PpYap1 through conserved cysteine residues during methanol metabolism in the yeast Pichia pastoris.
The methylotrophic yeast Pichia pastoris can grow on methanol as sole... | 7th October, 2009
| Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto
| Biosci Biotechnol Biochem. 2009 Jun;73(6):1404-11. Epub 2009 Jun 7.
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Proximity-based protein thiol oxidation by H2O2-scavenging peroxidases.
H2O2 acts as a signaling molecule by oxidizing critical thiol groups on... | 17th September, 2009
| German Cancer Research Center, Germany;
| J Biol Chem. 2009 Sep 15.
DOI Direct Link |
→View more research publications. |
YAP1 results (if any) from reagent suppliers | 
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YAP1 antibody (ab27981) | Abcam
Rabbit polyclonal to YAP1. YAP1 (also known as Yes associated protein 1) was originally identified as a transcription factor that binds to the SH3 domain of
...
http://www.abcam.com/YAP1-antibody-ab27981.html...
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Yap1 Antibody / Yap1 Antibodies
Yap1 Antibody / Yap1 Antibodies. ... Yap1 (yC-15) Antibody, sc-15620, goat IgG, C-terminus (Sc), WB, ELISA, S. cerevisiae. Yap1 (yN-18) Antibody, sc-15618 ...
http://www.scbt.com/table-yap1.html...
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YAP1 (phospho Y357) antibody (ab62751) | Abcam
Rabbit polyclonal to YAP1 (phospho Y357). YAP1 (also known as Yes associated protein 1) was originally identified as a transcription factor that binds to ...
http://www.abcam.com/YAP1-phospho-Y357-antibody-ab62751.html...
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Yap1 (yC-15) Antibody sc-15620
Yap1 (yC-15) Antibody sc-15620 Yap1 (yC-15) Antibody sc-15620.
http://www.scbt.com/ko/datasheet-15620-yap1-yc-15-antibody.h...
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YAP1 (phospho S127) antibody [EP1675Y] (ab76252) | Abcam
Rabbit monoclonal [EP1675Y] to YAP1 (phospho S127). YAP1 (also known as Yes associated protein 1) was originally identified as a transcription factor that
...
http://www.abcam.com/YAP1-phospho-S127-antibody-EP1675Y-ab76...
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YAP (H-125) Antibody sc-15407
Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage. Mol Cell. 29(3): 350-361. ...
http://www.scbt.com/datasheet-15407-yap-h-125-antibody.html...
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YAP1 antibodies: Cancer > Signal transduction > Other | Abcam
YAP1 antibodies. ... YAP1 (phospho S127) antibody [EP1675Y]. IHC-P, WB ... YAP1 antibody [EP1674Y]. Flow Cyt, IP, WB, ICC/IF, IHC-P ...
http://www.abcam.com/index.html?t=165205&pt=1&c=4295&ei=&mu=...
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