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BAIAP2
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 14752106 |
IRSp53, when activated by small GTPases, participates in F-actin reorganization not only in an SH3-dependent manner but also in a manner dependent on the activity of the IRSp53/MIM homology domain |
| 17115031 |
These results support a model whereby the synergic bundling activity of the IRSp53-Eps8 complex, regulated by Cdc42, contributes to the generation of actin bundles, thus promoting filopodial protrusions. |
| 14596909 |
LIN7B is a partner of IRSp53 anchoring the actin-based membrane cytoskeleton at cell-cell contacts. |
| 15673667 |
These results suggest that PSD-95 interaction is an important determinant of synaptic IRSp53 localization and that the SH3 domain of IRSp53 links activated Rac1/Cdc42 to downstream effectors for the regulation of spine morphogenesis. |
| 16702231 |
Therefore, IRSp53 optimizes the activity of the WAVE2 complex in the presence of activated Rac and PIP(3). |
| 17003044 |
The mechanism of membrane deforamtion induced by the IRSp53 RCB domain is reported. |
| 17371834 |
Together, these data reveal that interplay between actin dynamics and a novel membrane-deformation activity promotes cell motility and morphogenesis. |
| 15635447 |
IRSp53 comprises a central SH3 domain, which binds to proline-rich regions of a wide range of actin regulators, and a conserved N-terminal IRSp53/MIM homology domain that harbours F-actin-bundling activity. Presents crystal structure of this novel domain |
Recent Publications on BAIAP2: |  |
Cdc42- and IRSp53-dependent contractile filopodia tether presumptive lens and retina to coordinate epithelial invagination.
The vertebrate lens provides an excellent model with which to study the... | 13th October, 2009
| The Visual Systems Group, Children's Hospital Research Foundation,
| Development. 2009 Nov;136(21):3657-67.
DOI Direct Link |
Case-control study of six genes asymmetrically expressed in the two cerebral hemispheres: association of BAIAP2 with attention-deficit/hyperactivity disorder.
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is a... | 8th September, 2009
| Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona,
| Biol Psychiatry. 2009 Nov 15;66(10):926-34. Epub 2009 Sep 5.
DOI Direct Link |
SPIN90-IRSp53 complex participates in Rac-induced membrane ruffling.
SPIN90 is a key regulator of actin cytoskeletal organization. Using the... | 12th August, 2009
| Bio Imaging Research Center, Cell Dynamics Research Center, Department of
| Exp Cell Res. 2009 Aug 15;315(14):2410-9. Epub 2009 May 19.
DOI Direct Link |
IRSp53 links the enterohemorrhagic E. coli effectors Tir and EspFU for actin pedestal formation.
Actin pedestal formation by pathogenic E. coli requires signaling by the... | 5th May, 2009
| Signalling and Motility Group, Helmholtz Centre for Infection Research,
| Cell Host Microbe. 2009 Mar 19;5(3):244-58.
DOI Direct Link |
Putting enterohemorrhagic E. coli on a pedestal.
Many pathogenic bacteria exploit host cytoskeletal pathways to promote... | 5th May, 2009
| Department of Medicine, Division of Infectious Diseases, Massachusetts
| Cell Host Microbe. 2009 Mar 19;5(3):215-7.
DOI Direct Link |
→View more research publications. |
BAIAP2 results (if any) from reagent suppliers | 
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Signal Transduction Antibodies :: Page 7
BAI1 Antibody, 48-300, H, IHC, Brain-Specific Angiogenesis Inhibitor 1. BAIAP2 Antibody, 45-016, H, E, WB, (CT) BAIAP2 (isoform 2). BAIAP2 Antibody, 45-017 ...
http://www.prosci-inc.com/shop/catalog1/Signal-Transduction-...
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IRSp53 (W-20) Antibody sc-50011
Human, BAIAP2, 10458, 17q25.3, NM_006340, NM_017450, NM_017451 · Q9UQB8 · 605475 . Mouse, Baiap2, 108100, 11 E2, Q8BKX1 ...
http://www.scbt.com/datasheet-50011-irsp53-w-20-antibody.htm...
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IHC verified Antibodies - Orbigen Inc. - Orbigen Inc.
PAB-10427, BAI1-associated protein 2 (BAIAP2) polyclonal antibody · NM_006340, 100 µg, $210.00. PAB-10428, BAI1-associated protein 3 (BAIAP3) polyclonal ...
http://www.orbigen.com/commerce/catalog/spcategory.jsp?categ...
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Abgent - Neurosciences Antibodies
AP8171a, BAI2 Antibody (C-term), IHC, E, H. AP8172a, BAI3 Antibody (C-term), IHC , E, H. AP8174a, BAIAP2 Antibody (C-term), WB, IHC, E, H, M ...
http://www.abgent.com/products/category/neurosciences...
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Antibodies available - Antibodies | Imgenex
IMG-3041, BAIAP2, BAI1-associated protein 2, BAP2, IRSP53, Purified, ... IMG- 3430, BAIAP2 (isoform 3), BAP2, IRSP53, BAI1-associated protein 2, Purified, ...
http://www.imgenex.com/alphabetic_antibody_list.php?done=dis...
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Abgent - Cell and Function Antibodies
AP8174a, BAIAP2 Antibody (C-term), WB, IHC, E, H, M. AT1264aNEW, BAIAP2L1 monoclonal antibody (M01), ELISA,IHC-P,S-ELISA,WB-Ce,WB-Re, H ...
http://www.abgent.com/products/category/cell_function...
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BAI1 associated protein 2 isoform 3 peptide (509-520) (ab19041 ...
BAIAP2, a target of p53, has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic me...
http://www.abcam.com/BAI1-associated-protein-2-isoform-3-pep...
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