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TACC3


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Symbol:TACC3
Name(s):transforming, acidic coiled-coil containing protein 3
Type:protein-coding
Organism:Homo sapiens
Synonyms:ERIC1, MGC117382, MGC133242
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17914111 Aurora-A and TACC3 interaction is important to control the mitotic spindle organization required for proper chromosome segregation.
17675670 TACC3 has an essential role in spindle assembly and cellular survival
12389629 REVIEW: genetics, expression, gene expression regulation, and function studies

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDGCN5 general control of amino-acid synthesis 5-like 2transforming, acidic coiled-coil containing protein 3TACC3 interacts with hGCN5L2.-Pubmed
HPRDtranscription termination factor, RNA polymerase IItransforming, acidic coiled-coil containing protein 3--Pubmed
HPRDtranscription termination factor, RNA polymerase IItransforming, acidic coiled-coil containing protein 3--Pubmed
BINDtranscription termination factor, RNA polymerase IItransforming, acidic coiled-coil containing protein 3HuF2 interacts with TACC3.-Pubmed
HPRDA-kinase anchor protein 9 isoform 1transforming, acidic coiled-coil containing protein 3--Pubmed
HPRDA-kinase anchor protein 9 isoform 1transforming, acidic coiled-coil containing protein 3--Pubmed

Recent Publications on TACC3:

Pubmed Logo
Cdh1 controls the stability of TACC3.
Transforming acidic coiled-coil protein 3 (TACC3) was reported to be...
14th October, 2009
Graduate Institute of Life Sciences, National Defense Medical Center and Cell Cycle. 2009 Nov;8(21):3537-3544. Epub 2009 Nov 27.
TOGp regulates microtubule assembly and density during mitosis and contributes to chromosome directional instability.
TOGp, a member of the XMAP215 MAP family, is required for bipolar mitotic...
14th October, 2009
Department of Biological Sciences, Lehigh University, Bethlehem, Cell Motil Cytoskeleton. 2009 Aug;66(8):535-45.
DOI Direct Link
Anticancer effects on TACC3 by treatment of paclitaxel in HPV-18 positive cervical carcinoma cells.
Previously, we used proteome analysis to identify transforming acidic...
26th March, 2009
Department of Obstetrics and Gynecology, The Catholic University of Korea, Oncol Rep. 2009 Feb;21(2):549-57.
Abnormal liver development and resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity in mice carrying a mutation in the DNA-binding domain of the aryl hydrocarbon receptor.
The aryl hydrocarbon receptor (AHR) is known for its role in the adaptive...
24th December, 2008
McArdle Laboratory for Cancer Research, University of Wisconsin School of Toxicol Sci. 2008 Nov;106(1):83-92. Epub 2008 Jul 27.
DOI Direct Link
Xenopus TACC3/maskin is not required for microtubule stability but is required for anchoring microtubules at the centrosome.
Members of the transforming acidic coiled coil (TACC) protein family are...
23rd December, 2008
Department of Biochemistry, University of Wisconsin-Madison, Madison, WI Mol Biol Cell. 2008 Aug;19(8):3347-56. Epub 2008 May 28.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7462447 Methods for evaluating susceptibility to a bone homeostasis disorder
6607899 Amplification-based cloning method
6706867 DNA array sequence selection
6753154 Human AZU-1 gene, variants thereof and expressed gene products
6887901 Lipoxin compounds and their use in treating cell proliferative disorders

View more patents.

TACC3 results (if any) from reagent suppliers

Google CSE Logo
TACC3 antibody (ab56595) | Abcam
Mouse monoclonal to TACC3. TACC3 may be involved in the control of cell growth and differentiation. It may also contribute to cancer: expression of TACC3 is
...
http://www.abcam.com/TACC3-antibody-ab56595.html...

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TACC3 (T-17) Antibody sc-5885
See how others have used TACC3 (T-17): sc-5885 antibody and or TACC3 (T-17) antibody ... Aberrations of TACC1 and TACC3 are associated with ovarian cancer.
...
http://www.scbt.com/datasheet-5885-tacc3-t-17-antibody.html...

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ORDERING INFORMATION
Transforming acidic coiled-coil containing protein 3 (TACC3; also know as ERIC-1 ) is ... Over amino acids 689 - 838, human TACC3 shares 79% aa identity with ...
http://www.rndsystems.com/pdf/AF5720.pdf...

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TACC3 (D-2) Antibody sc-48368
TACC3 (D-2): sc-48368. Immunoperoxidase staining of formalin fixed, paraffin- embedded ... Western blot analysis of TACC3 expression in non-transfected 293T:
...
http://www.scbt.com/datasheet-48368-tacc3-d-2-antibody.html...

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Purified Anti-ch-TOG Antibody - BioLegend
Interaction: TACC1, TACC3, tubulin. Antigen References: 1. Charrasse, S., et al. , 1995. Eur. J. Biochem. 234:406. ... Purified anti-TACC3, Poly6188, IF,WB ...
http://www.biolegend.com/purified-anti-ch-tog-antibody-2191....

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TACC3 (S-18) Antibody sc-5887
TACC3 shRNA (h) Lentiviral Particles, sc-36602-V, 200 µl ... TACC3 (S-18): sc- 5887. Western blot analysis of TACC3 expression in non-transfected: sc-117752
...
http://www.scbt.com/datasheet-5887-tacc3-s-18-antibody.html...

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TACC3 - R&D Systems
TACC3. Products By Product Type. All Products for this Molecule · Antibodies · Legal; |; Sitemap. United States (change country); |; (800) 343-7475 ...
http://www.rndsystems.com/molecule_detail.aspx?m=4400...

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