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TADA3L


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Symbol:TADA3L
Name(s):transcriptional adaptor 3 (NGG1 homolog, yeast)-like
Type:protein-coding
Organism:Homo sapiens
Synonyms:ADA3, FLJ20221, FLJ21329, hADA3
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18089809 Role of Ada3 in histone acetyltransferase recruitment to estrogen-responsive target gene promoters and for estrogen-dependent proliferation of breast cancer cells.
17452980 p14ARF signals through hAda3 to stimulate p53 acetylation and the induction of cell senescence
12235159 Results demonstrate that human papilloma virus 16 E6 oncoprotein inhibits the RXR(alpha)-mediated transactivation of target genes, implying that perturbation of RXR-mediated transactivation by E6 could contribute to HPV oncogenesis.
17272277 human Ada3 has an essential role in p53 acetylation
12138191 Data identify hADA3, human homologue of the yeast transcriptional coactivator yADA3, as a novel human papillomavirus oncoprotein E6-interacting protein and a target of E6-induced degradation.
15496419 results demonstrate that transcriptional adaptor ADA3 protein directly binds to human estrogen receptor alpha and beta and enhances the transcription of estrogen receptor-responsive genes

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDE1A binding protein p300transcriptional adaptor 3-like isoform a--Pubmed
HPRDE1A binding protein p300transcriptional adaptor 3-like isoform a--Pubmed
HPRDEstrogen receptor, alphatranscriptional adaptor 3-like isoform a--Pubmed
HPRDestrogen receptor 1ADA3--Pubmed
HPRDretinoic acid receptor, alpha isoform atranscriptional adaptor 3-like isoform a--Pubmed
HPRDretinoic acid receptor, alpha isoform atranscriptional adaptor 3-like isoform a--Pubmed
HPRDretinoid X receptor, alphatranscriptional adaptor 3-like isoform a--Pubmed
HPRDretinoid X receptor, alphatranscriptional adaptor 3-like isoform a--Pubmed
HPRDtumor protein p53transcriptional adaptor 3-like isoform a--Pubmed
HPRDtumor protein p53transcriptional adaptor 3-like isoform a--Pubmed

Recent Publications on TADA3L:

Pubmed Logo
HPV16 E6-induced and E6AP-dependent inhibition of the transcriptional coactivator hADA3 in human cervical carcinoma cells.
To determine whether there exists an additional pathway of E6 that is...
2nd April, 2009
Women's Reproductive Health Laboratory of Zhejiang Province, Department of Cancer Invest. 2009 Mar;27(3):298-306.
DOI Direct Link
The STAGA subunit ADA2b is an important regulator of human GCN5 catalysis.
Human STAGA is a multisubunit transcriptional coactivator containing the...
15th January, 2009
Laboratory of Biochemistry and Molecular Biology, The Rockefeller Mol Cell Biol. 2009 Jan;29(1):266-80. Epub 2008 Oct 20.
DOI Direct Link
Ankyrin repeats-containing cofactors interact with ADA3 and modulate its co-activator function.
ANCO (ankyrin repeats-containing cofactor)-1 and ANCO-2 are a family of...
31st July, 2008
Department of Pharmacology, University of Medicine and Dentistry of New Biochem J. 2008 Jul 15;413(2):349-57.
DOI Direct Link
hADA2a and hADA3: new players in beta-catenin signaling.
ANCO (ankyrin repeats-containing cofactor)-1 and ANCO-2 are a family of...
11th June, 2008
Department of Medicine, Division of Hematology and Medical Oncology, Cancer Biol Ther. 2008 Jan;7(1):129-30. Epub 2008 Feb 11.
hADA2a and hADA3 are required for acetylation, transcriptional activity and proliferative effects of beta-catenin.
Beta-catenin is the key transcriptional activator of the Wnt pathway...
11th June, 2008
Department of Medicine, University of California, Irvine, California, USA. Cancer Biol Ther. 2008 Jan;7(1):120-8. Epub 2007 Oct 19.

View more research publications.

TADA3L results (if any) from reagent suppliers

Google CSE Logo
Protein Modification / Acetylation - Protein Modification Antibody
AM1190a, SUV39H1 Antibody, WB, E, H, M. AP1190a, SUV39H1 Antibody, WB, IHC, E, H , M. AT4135a, TADA3L monoclonal antibody (M02), ELISA,WB-Re,WB-Tr, H ...
http://www.abgent.com/products/category/protein_modification...

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Antibody Products - IgG Polyclonal Antibodies - GenWay
18-003-43346, TADA3L (transcriptional adaptor 3 (NGG1 homolog. yeast)-like) Related Product Names: - TADA3L; ADA3, FLJ20221, FLJ21329, hADA3 ...
http://www.genwaybio.com/all_polyclonal_antibodies.php?fl=T...

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ADA3 (TADAD25A) Antibody sc-81119
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, TADA3L, 10474, 3p25.3, NM_006354, ...
http://www.scbt.com/datasheet-81119-ada3-tadad25a-antibody.h...

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Abgent - Cell and Structure Antibodies - Cell_structure
AT4135aNEW, TADA3L monoclonal antibody (M02), ELISA,WB-Re,WB-Tr, H. AT4149aNEW, TAGLN monoclonal antibody (M01), ELISA,WB-Re,WB-Tr, H ...
http://www.abgent.com/products/category/cell_function/cell_s...

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ADA3 (m4): 293T Lysate sc-118236
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Tada3l, 101206, 6 E3, Q8R0L9 ...
http://www.scbt.com/datasheet-118236-ada3-m4-293t-lysate.htm...

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Abgent - Cancer Antibodies - Cancer
AT4133aNEW, TACC3 monoclonal antibody (M02), ELISA,IHC-P,WB-Ce,WB-Re, H. AT4135a NEW, TADA3L monoclonal antibody (M02), ELISA,WB-Re,WB-Tr, H ...
http://www.abgent.com/products/category/cell_function/cancer...

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ADA3 (TADAD25A) Antibody sc-81119
Spezies, Gen, Gen ID, Chromosomaler Locus, mRNA (Isoform) Accession #, Protein Accession #, OMIM™ Nummer. Human, TADA3L, 10474, 3p25.3, NM_006354, NM_133480
...
http://www.scbt.com/de/datasheet-81119-ada3-tadad25a-antibod...

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