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UBD


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Gene DB Home
Symbol:UBD
Name(s):ubiquitin D
Type:protein-coding
Organism:Homo sapiens
Synonyms:FAT10, GABBR1, UBD-3
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17971048 Observational study of gene-disease association. (HuGE Navigator)
17889673 The identification of an E1-like protein, termed E1-L2, that activates both ubiquitin and another ubiquitin-like protein, FAT10, is reported.
16707496 A deletion mutant of NUB1L lacking the UBL domain is still able to bind FAT10 but not the proteasome and no longer accelerates FAT10 degradation
15831455 FAT10 is degraded by the proteasome in ubiqitin-independent manner.
12730673 FAT10 may modulate tumorigenesis through its reported interaction with the MAD2 spindle-assembly checkpoint protein.
16495226 high levels of FAT10 protein in cells lead to increased mitotic nondisjunction and chromosome instability, which is mediated by an abbreviated mitotic phase and reduction in the kinetochore localization of MAD2 during prometaphase
16495380 Immunohistochemical studies demonstrated increased FAT10 expression in HIV-associated nephropathy and in autosomal dominant polycystic kidney disease.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDMAD2-like 1ubiquitin D--Pubmed
BINDMAD2-like 1ubiquitin DMAD2 interacts with FAT10.-Pubmed
HPRDUbiquitin DNEDD8 ultimate buster-1--Pubmed
HPRDubiquitin DNEDD8 ultimate buster 1--Pubmed

Recent Publications on UBD:

Pubmed Logo
Acute bladder inflammation differentially affects rat spinal visceral nociceptive neurons.
The present investigation examined the effect of inflammation produced by...
14th October, 2009
Department of Anesthesiology, University of Alabama at Birmingham, 1530 Neurosci Lett. 2009 Oct 12.
DOI Direct Link
A regulatory single nucleotide polymorphism in the ubiquitin D gene associated with celiac disease.
An aberrant immune response triggered by dietary gluten is the main...
8th October, 2009
Immunogenetics Research Laboratory, Hospital de Cruces, Barakaldo-Bizkaia, Hum Immunol. 2009 Oct 3.
DOI Direct Link
Ubiquitin-binding domains - from structures to functions.
Ubiquitin-binding domains (UBDs) are modular elements that bind...
2nd October, 2009
Institute of Biochemistry II and Cluster of Excellence "Macromolecular Nat Rev Mol Cell Biol. 2009 Oct;10(10):659-71.
DOI Direct Link
VIRUS-INDUCED AUTOIMMUNE DIABETES IN THE LEW.1WR1 RAT REQUIRES Iddm14 AND A GENETIC LOCUS PROXIMAL TO THE MAJOR HISTOCOMPATIBILITY COMPLEX.
Objective: To identify genes that confer susceptibility to autoimmune...
2nd September, 2009
Department of Microbiology and Immunology, Center for Immunogenetics and Diabetes. 2009 Aug 31.
DOI Direct Link
Effects of oxytocin and prolactin on stress-induced bladder hypersensitivity in female rats.
Anecdotal evidence suggests that chronic bladder pain improves while...
15th July, 2009
Department of Pediatrics, Division of Pediatric Hematology and Oncology, J Pain. 2009 Oct;10(10):1065-72.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
6745855 Method and system for hydraulic friction controlled drilling and completing geopressured wells utilizing concentric drill strings
7188683 Drilling method
7199083 Self-generating foamed drilling fluids
7212509 Method for regulating a frequency offset in a base-station receiver of a data communications system
7237623 Method for pressurized mud cap and reverse circulation drilling from a floating drilling rig using a sealed marine riser

View more patents.

UBD results (if any) from reagent suppliers

Google CSE Logo
FAT10 (FL-165) Antibody sc-67203
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, UBD, 10537, 6p22.1, NM_006398 ...
http://www.scbt.com/datasheet-67203-fat10-fl-165-antibody.ht...

Thumbshot
IMPORTANT INFORMATION: PLEASE NOTE:
The presence of a UBD in a protein indicates that it can interact with ubiquitin or a ubiquitinylated protein and might be regulated by ubiquitinylation. ...
http://www.biomol.com/SiteData/docs/ProductData/UW8995.pdf...

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FAT10 (T-18) Antibody sc-51086
Species, 遺伝子名, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. ヒト, UBD, 10537, 6p22.1, NM_006398 · O15205
...
http://www.scbt.com/ja/datasheet-51086-fat10-t-18-antibody.h...

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FAT10 (FL-165) Antibody sc-67203
种属, 基因名称, 基因ID, 染色质位置, 亚型(mRNA)即位号码, 蛋白质即位号码, OMIM™ 号码. 人类, UBD, 10537, 6p22.1, NM_006398 · O15205 ...
http://www.scbt.com/zh/datasheet-67203-fat10-fl-165-antibody...

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FAT10 (FL-165) Antibody sc-67203
Humano, UBD, 10537, 6p22.1, NM_006398 · O15205 · 606050. camundongo, Ubd, 24108, 17 B1, P63072, N/A. Informacoes sobre ordens ...
http://www.scbt.com/pt/datasheet-67203-fat10-fl-165-antibody...

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