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HBXIP
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18032378 |
HBXIP is a critical target of viral HBx for promoting genetic instability through formation of defective spindles and subsequent aberrant chromosome segregation. |
| 16176273 |
suppressor of var1, 3-like 1 protein interacts with HBXIP, previously identified as a cofactor of survivin in suppression of apoptosis |
| 11788598 |
Hepatitis B virus pX interacts with HBXAP |
| 17050029 |
The codon-38 change in genotype C is an independent risk factor for the development of HCC and may serve as a useful molecular marker for predicting the clinical outcomes in patients infected with HBV. |
| 15955450 |
HBXIP up-regulates LTA expression in hepatocytes. |
| 16055925 |
HBXIP sensitizes HepG2 cells to UV light-induced DNA damage. |
| 11925594 |
Elevated levels of GDN/PN1 and XIP mRNAs induced by Allitridi provide valuable molecular evidence for elucidating garlic's efficacies against neurodegenerative and inflammatory diseases. |
| 12773388 |
Survivin-HBXIP complexes, but neither survivin nor HBXIP individually, bind pro-caspase-9, preventing its recruitment to Apaf1, and thereby selectively suppressing apoptosis. |
| 17428866 |
Hepatitis B virus X protein stimulates the mitochondrial translocation of Raf-1 via oxidative stress |
Recent Publications on HBXIP: |  |
Increased expression of inhibitor of apoptosis proteins, survivin and XIAP, in non-small cell lung carcinoma.
Members of the inhibitor of apoptosis protein (IAP) family, survivin and... | 4th November, 2009
| Department of Pneumology and Thoracic Surgery, University Hospital
| Int J Oncol. 2009 Dec;35(6):1449-1462.
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Involvement of hepatitis B X-interacting protein (HBXIP) in proliferation regulation of cells.
AIM: To investigate the effect of Hepatitis B X-interacting protein... | 1st May, 2009
| Departments of Biochemistry, College of Life Sciences, Nankai University,
| Acta Pharmacol Sin. 2007 Mar;28(3):431-8.
DOI Direct Link |
Promotion of cell proliferation by HBXIP via upregulation of human telomerase reverse transcriptase in human mesenchymal stem cells.
AIM: We previously found that the hepatitis B X-interacting protein... | 25th April, 2009
| Departments of Biochemistry, Tianjin Key Laboratory of Microbial
| Acta Pharmacol Sin. 2008 Jan;29(1):83-9.
DOI Direct Link |
Interaction of hepatitis B viral oncoprotein with cellular target HBXIP dysregulates centrosome dynamics and mitotic spindle formation.
Hepatitis B virus infection is associated with hepatocellular carcinoma,... | 3rd April, 2008
| Program on Apoptosis and Cell Death Research, Burnham Institute for
| J Biol Chem. 2008 Feb 1;283(5):2793-803. Epub 2007 Nov 21.
DOI Direct Link |
HBXIP, cellular target of hepatitis B virus oncoprotein, is a regulator of centrosome dynamics and cytokinesis.
Hepatitis B virus accounts for more than 1 million cancer deaths annually,... | 9th December, 2006
| Burnham Institute for Medical Research, La Jolla, California and ISIS
| Cancer Res. 2006 Sep 15;66(18):9099-107.
DOI Direct Link |
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