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AGR2


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Symbol:AGR2
Name(s):anterior gradient homolog 2 (Xenopus laevis)
Type:protein-coding
Organism:Homo sapiens
Synonyms:AG2, GOB-4, HAG-2, XAG-2
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
16222343 Observational study of gene-disease association. (HuGE Navigator)
17694278 Elevated levels of AGR2 are associated with the metastatic potential of breast cancer
17457305 increased AGR2 expression is a valuable prognostic factor to predict the clinical outcome of the prostate cancer patients.
16551856 A prognostic effect of AGR2 for overall survival could be shown, which became independently significant for the group of nodal-negative tumors.
15834940 AGR2 may serve as a potential therapeutic target and/or molecular marker for prostate cancer.
12592373 hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan.
15935701 specific induction of Hag2 and Hag3 during hormone-induced breast carcinomas further support developmental specificity for the PDI/ERp family members

Recent Publications on AGR2:

Pubmed Logo
The metastasis-associated anterior gradient 2 protein is correlated with poor survival of breast cancer patients.
The secreted metastasis-inducing protein, human anterior gradient 2...
17th October, 2009
Cancer Tissue Bank Research Centre, University of Liverpool, UK. Am J Pathol. 2009 Nov;175(5):1848-57. Epub 2009 Oct 15.
DOI Direct Link
Prognostic significance of AGR2 in pancreatic ductal adenocarcinoma.
BACKGROUND/AIMS: The human Anterior Gradient-2 (AGR2) is strongly...
8th October, 2009
Institute of Surgical Pathology, Department of Pathology, University Histol Histopathol. 2009 Sep;24(9):1121-8.
SAM pointed domain ETS factor (SPDEF) regulates terminal differentiation and maturation of intestinal goblet cells.
Background and Aims: SPDEF (also termed PDEF or PSE) is an ETS family...
30th September, 2009
Divisions of Gastroenterology, Hepatology and Nutrition, University of Exp Cell Res. 2009 Sep 26.
DOI Direct Link
Identification of candidate biomarkers of therapeutic response to docetaxel by proteomic profiling.
Docetaxel chemotherapy improves symptoms and survival in men with...
24th September, 2009
Cancer Research Program, Garvan Institute of Medical Research, Sydney, Cancer Res. 2009 Oct 1;69(19):7696-703. Epub 2009 Sep 22.
DOI Direct Link
SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production.
Various acute and chronic inflammatory stimuli increase the number and...
18th September, 2009
J Clin Invest. 2009 Oct;119(10):2914-24. doi: 10.1172/JCI39731. Epub 2009
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7612181 Dual variable domain immunoglobulin and uses thereof
4446525 Numerical control with paramacro capability
5093902 Memory control apparatus for accessing an image memory in cycle stealing fashion to read and write videotex signals
6519257 ATM telecommunications systems and method for routing narrow band traffic
6859932 Relocation format for linking

View more patents.

AGR2 results (if any) from reagent suppliers

Google CSE Logo
Anterior Gradient 2 antibody (ab43043) | Abcam
Anterior gradient 2 (AGR2) and Anterior gradient 3 (AGR3) are recently discovered ... Rabbit anti-AGR2 antibody ab43043 was used as primary antibody at
a ...
http://www.abcam.com/Anterior-Gradient-2-antibody-ab43043.ht...

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AGR2 (6C5) Antibody sc-101211
mouse monoclonal IgG2b, 100 µg/ml; raised against recombinant AGR2 of human ... AGR2 (6C5): sc-101211 Western blot analysis of AGR2 expression in human AGR2 ...
http://www.scbt.com/datasheet-101211-agr2-6c5-antibody.html...

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AGR2 Antibody Anterior Gradient 2 Homolog
AGR2 Antibody 49-258, ... Immunogen. AGR2 antibody was raised against synthetic peptides corresponding to amino acids 55-72 of AGR2. (Human) ...
http://www.prosci-inc.com/shop/catalog1/AGR2-Antibody-p-3305...

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Anterior Gradient 2 (AGR2) Antibody (Center)
Anterior Gradient 2 (AGR2) Antibody (Center) Cell Function, Anterior Gradient 2 (AGR2) Antibody (Center) Cancer.
http://www.abgent.com/products/catalog_no/AP6279c...

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AGR2 (T-17) Antibody sc-54561
goat polyclonal IgG, 200µg/ml; epitope mapping near the N-terminus of AGR2 of mouse origin; recommended for detection of AGR2 of m and r origin by WB, IP, ...
http://www.scbt.com/datasheet-54561-agr2-t-17-antibody.html...

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Polyclonal Antibody to Anterior Gradient 2 (AGR2) Homolog
AGR2, GOB-4, anterior gradient 2 homolog, XAG-2 homolog long protein, Secreted cement gland protein XAG-2 homolog, AG-2 protein, hAG-2, HPC8, ...
http://www.imgenex.com/antibody_details.php?catalog=IMG-5279...

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AGR2 (Y-14) Antibody sc-54562
AGR2 shRNA (h) Lentiviral Particles, sc-61956-V, 200 µl ... Western blot analysis of AGR2 expression in MCF7 whole cell lysate. Download ...
http://www.scbt.com/datasheet-54562-agr2-y-14-antibody.html...

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