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TACC2


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Symbol:TACC2
Name(s):transforming, acidic coiled-coil containing protein 2
Type:protein-coding
Organism:Homo sapiens
Synonyms:AZU-1, ECTACC
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
14767476 GCN5L2 is a TACC2-binding protein.
15304323 Centrosomal TACC2 is required for mitotic spindle maintenance.
12620397 Defects in TACC2 expression may affect gene regulation, thus contributing to the pathogenesis of some tumors.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDCREB binding proteintransforming, acidic coiled-coil containing protein 2 isoform bTACC2 interacts with CBP.-Pubmed
BINDE1A binding protein p300transforming, acidic coiled-coil containing protein 2 isoform bTACC2 interacts with p300.-Pubmed
BINDGCN5 general control of amino-acid synthesis 5-like 2transforming, acidic coiled-coil containing protein 2 isoform bTACC2 interacts with hGCN5L2.-Pubmed
HPRDSWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 isoform atransforming, acidic coiled-coil containing protein 2 isoform a--Pubmed
HPRDSWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 isoform atransforming, acidic coiled-coil containing protein 2 isoform a--Pubmed
HPRDglioma-amplified sequence-41transforming, acidic coiled-coil containing protein 2 isoform a--Pubmed
HPRDglioma-amplified sequence-41transforming, acidic coiled-coil containing protein 2 isoform a--Pubmed
BINDp300/CBP-associated factortransforming, acidic coiled-coil containing protein 2 isoform bTACC2 interacts with pCAF.-Pubmed

Recent Publications on TACC2:

Pubmed Logo
Contributions to neutropenia from PFAAP5 (N4BP2L2), a novel protein mediating transcriptional repressor cooperation between Gfi1 and neutrophil elastase.
"Neutropenia" refers to deficient numbers of neutrophils, the most...
10th September, 2009
Department of Genome Sciences, University of Washington, Box 355065, Mol Cell Biol. 2009 Aug;29(16):4394-405. Epub 2009 Jun 8.
DOI Direct Link
Simian virus 40 large T antigen targets the microtubule-stabilizing protein TACC2.
The large T antigens of polyomaviruses target cellular proteins that...
13th August, 2009
Department of Medical Cell Biology, Institute of Molecular Embryology and J Cell Sci. 2009 Sep 1;122(Pt 17):3190-8. Epub 2009 Aug 11.
DOI Direct Link
Exploiting gene expression profiling to identify novel minimal residual disease markers of neuroblastoma.
PURPOSE: Minimal residual disease (MRD) presents a significant hurdle to...
20th December, 2008
Department of Pediatrics and Pathology, Memorial Sloan-Kettering Cancer Clin Cancer Res. 2008 Nov 1;14(21):7020-7.
DOI Direct Link
The TACC proteins: TACC-ling microtubule dynamics and centrosome function.
A major quest in cell biology is to understand the molecular mechanisms...
7th October, 2008
Cell and Developmental Biology Program, Centre for Genomic Regulation Trends Cell Biol. 2008 Aug;18(8):379-88. Epub 2008 Jul 23.
DOI Direct Link
The tale of two domains: proteomics and genomics analysis of SMYD2, a new histone methyltransferase.
Very little is known about SET- and MYND-containing protein 2 (SMYD2), a...
4th April, 2008
Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario Mol Cell Proteomics. 2008 Mar;7(3):560-72. Epub 2007 Dec 7.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7309585 121P1F1: a tissue specific protein highly expressed in various cancers
4754736 Method of controlling the fuel supply to internal combustion engines at acceleration
5305281 Multiple array memory device with staggered read/write for high speed data access
5866779 Recombinant gibberellin DNA and uses thereof
5908971 Crucifer ACC synthase and uses thereof

View more patents.

TACC2 results (if any) from reagent suppliers

Google CSE Logo
TACC2 antibody - GeneTex Inc. - Your source for monoclonal ...
Product Description, Rabbit polyclonal antibody to TACC2 (transforming, ... Specificity, This antibody is specific to the Human TACC2 protein. ...
http://www.genetex.com/WebPage/Product/ProductDetail.aspx?Ca...

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TACC2 (C-14) Antibody sc-5890
TACC2 shRNA (h) Lentiviral Particles, sc-37500-V, 200 µl, $595. TACC2 shRNA (m) Lentiviral Particles, sc-37501-V, 200 µl ...
http://www.scbt.com/datasheet-5890-tacc2-c-14-antibody.html...

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TACC2 antibodies: Cancer > Cell cycle > Cell division | Abcam
TACC2 antibodies. ... Applications (see key) & Reactivity (see key). Image Abreview Publication. ab17916 · TACC2 antibody. WB, ELISA. Rabbit polyclonal ...
http://www.abcam.com/index.html?t=109823&pt=1&c=4198&ei=&mu=...

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TACC2 siRNA (h) sc-37500
Click here for details. suitable control antibody: TACC2 (C-14): sc-5890; sqRT- PCR Primer also available: TACC2 (h)-PR: sc-37500-PR, 20 µl ...
http://www.scbt.com/datasheet-37500-tacc2-sirna-h.html...

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GeneTex Inc. - Your source for monoclonal, polyclonal, primary ...
WB, GTX110587 USD $188.30. APEX1 antibody. WB, GTX110558 USD $188.30. TACC2 antibody. WB, GTX110516 USD $188.30. EIF5A2 antibody. WB, GTX110510 USD $188.30
...
http://www.genetex.com/...

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TACC Antibody / TACC Antibodies
TACC2 (C-14) Antibody, sc-5890, goat IgG, C-terminus (h), WB, IF, ELISA, m, r, h ... TACC2 shRNA Plasmid (h): sc-37500-SH. TACC2 shRNA (h) ...
http://www.scbt.com/table-tacc.html...

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GeneTex Inc. - Your source for monoclonal, polyclonal, primary ...
30 Jun 2009 ... USD $188.30. STAT3 antibody. WB, GTX110587 USD $188.30. APEX1 antibody. WB, GTX110558 USD $188.30. TACC2 antibody. WB, GTX110516 USD $188.30 ...
http://www.genetex.com/WebPage/Public/StaticPage.aspx?page=A...

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