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YKT6


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Gene DB Home
Symbol:YKT6
Name(s):YKT6 v-SNARE homolog (S. cerevisiae)
Type:protein-coding
Organism:Homo sapiens
Synonyms:-
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
16821082 mRNA expression of CCT5, RGS3, and YKT6 was significantly up-regulated in p53-mutated tumors and associated with a low response rate to docetaxel.
12388752 Data suggest that GS15 exists in a distinct SNARE complex that contains syntaxin5, GS28, and Ykt6, and may be involved in both ER-to-Golgi and intra-Golgi transport.
11884350 abnormalities in the SNARE complex could represent a molecular substrate for abnormalities of neural connectivity in severe mental disorders
14607937 N-ethylmaleimide-sensitive factor-dependent SNARE-priming complex disassembly is required for efficient exocytosis from mast cells.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDYKT6 v-SNARE proteinblocked early in transport 1 homolog like isoform 2--Pubmed
HPRDYKT6 v-SNARE proteinblocked early in transport 1 homolog like isoform 2--Pubmed

Recent Publications on YKT6:

Pubmed Logo
Functional analysis of GS28, an intra-Golgi SNARE, in Caenorhabditis elegans.
Intra-Golgi retrograde transport is assumed to maintain Golgi function by...
25th July, 2009
Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo Genes Cells. 2009 Aug;14(8):1003-13. Epub 2009 Jul 17.
DOI Direct Link
Blocking the secretion of saliva by silencing the HlYkt6 gene in the tick Haemaphysalis longicornis.
Soluble N-ethylmaleimide-sensitive fusion protein attachment protein...
25th July, 2009
National Research Center for Protozoan Diseases, Obihiro University of Insect Biochem Mol Biol. 2009 May-Jun;39(5-6):372-81. Epub 2009 Mar 27.
DOI Direct Link
Identification of gene transcripts in rat frontal cortex that are regulated by repeated electroconvulsive seizure treatment.
BACKGROUND/AIMS: Electroconvulsive therapy (ECT) is an effective treatment...
17th April, 2009
Division of Mental Health and Substance Abuse Research, National Health Neuropsychobiology. 2008;58(3-4):171-7. Epub 2009 Jan 14.
DOI Direct Link
Depalmitoylation of Ykt6 prevents its entry into the multivesicular body pathway.
The dually lipidated SNARE Ykt6 is found on intracellular membranes and in...
17th December, 2008
Department of Biology, Biochemistry Section, University of Osnabruck, Traffic. 2008 Sep;9(9):1510-21. Epub 2008 Jun 6.
DOI Direct Link
Farnesylation of the SNARE protein Ykt6 increases its stability and helical folding.
The evolutionarily conserved soluble N-ethylmaleimide-sensitive factor...
2nd July, 2008
Abteilung Physikalische Biochemie, Max-Planck-Institut fur molekulare J Mol Biol. 2008 Apr 11;377(5):1334-45. Epub 2008 Feb 13.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7598031 Method for the detection of gene transcripts in blood and uses thereof
6902887 Methods for monitoring multiple gene expression
7101990 Bax-responsive genes for drug target identification in yeast and fungi
7186513 Methods for monitoring multiple gene expression
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector

View more patents.

YKT6 results (if any) from reagent suppliers

Google CSE Logo
v-SNARE Ykt6p (K-16) Antibody sc-10835
Possible involvement of CCT5, RGS3, and YKT6 genes up-regulated in p53-mutated tumors in resistance to docetaxel in human breast cancers. Breast Cancer Res.
...
http://www.scbt.com/datasheet-10835-v-snare-ykt6p-k-16-antib...

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Abgent Antibodies and Peptides
AP6674a, Sestrin-2 Antibody (N-term), WB, E, H, 2009-09-30. AP6685b, YKT6 Antibody (C-term), WB, E, H, 2009-09-30. AP6693a, RAN Antibody (N-term), WB, E,
H ...
http://www.abgent.com/products/new_release...

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v-SNARE Ykt6p (FL-198) Antibody sc-30097
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIMâ„¢ Number. Human, YKT6, 10652, 7p13, NM_006555 ...
http://www.scbt.com/datasheet-30097-v-snare-ykt6p-fl-198-ant...

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Abgent - Cancer Antibodies - Cancer
AT4553aNEW, XRCC5 monoclonal antibody (M02), ELISA,IHC-P,WB-Ce,WB-Re, H. AP6685b NEW, YKT6 Antibody (C-term), WB, E, H ...
http://www.abgent.com/products/category/cell_function/cancer...

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Syntaxin Antibody / Syntaxin Antibodies
Syntaxin 5 also exists in a SNARE complex containing Golgi Snare (GS) 28, GS15 and Ykt6. Syntaxin 6 facilitates homotypic fusion of immature secretory ...
http://www.scbt.com/table-syntaxin.html...

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Abcam antibodies and reagents product map
... VTI1B proteins and peptides (1) · YKT6 antibodies (1) · ZDHHC17 antibodies ( 3) · ZDHHC17 proteins and peptides (1) · alpha+beta SNAP antibodies (3) ...
http://www.abcam.com/index.html?c=2105...

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