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GNA13
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17595347 |
role in regulating ASK1 expression levels |
| 17878759 |
provides first examination of Galpha12 and Galpha13 in the human heart, demonstrating selective activation of human atrial Galpha12 and Galpha13 by endothelin and angiotensin receptors, respectively |
| 17493936 |
analysis of a novel cross-talk exerted from the LPA/Galpha(13)/p115RhoGEF/RhoA pathway to the beta(2)-adrenergic receptor/Galpha(s)/adenylyl cyclase pathway |
| 17449226 |
Distinct regions of Galpha13 participate in its regulatory interactions with RGS homology domain-containing RhoGEFs. |
| 12297512 |
co-stimulation of G(12/13) and G(i) pathways is sufficient to activate GPIIb/IIIa in human platelets in a mechanism that involves intracellular calcium |
| 16046415 |
Galpha13-induced VASP phosphorylation that involves activation of RhoA and MEKK1, phosphorylation and degradation of IkappaB, release of PKA catalytic subunit from the complex with IkappaB and NF-kappaB, and subsequent phosphorylation of VASP |
| 17056591 |
Galpha13-Rho signaling axis is required for SDF-1-induced migration through CXCR4 |
| 11976333 |
Galpha12 and Galpha13 negatively regulate the adhesive functions of cadherin |
| 15735747 |
Several features of a typical alpha/RGS interaction are preserved in the alpha(13)/p115RhoGEF interaction. |
| 16787920 |
Results identify the G12 family proteins Galpha12 and 13 as important regulators of prostate cancer invasion and suggest that these proteins may be targeted to limit invasion- and metastasis-induced prostate cancer patient mortality. | →View more information from publications. |
Interacting gene products |
| Interaction Type |
Gene 1 |
Gene 2 |
Interaction description |
Complex |
Publication Link |
| HPRD | Cadherin 1 | guanine nucleotide binding protein, alpha 13 | - | - | Pubmed |
| HPRD | E-cadherin | Guanine nucleotide binding protein, alpha 13 | - | - | Pubmed |
| HPRD | Cadherin 2 | guanine nucleotide binding protein, alpha 13 | - | - | Pubmed |
| HPRD | cadherin 2, type 1 preproprotein | Guanine nucleotide binding protein, alpha 13 | - | - | Pubmed |
| HPRD | Beta catenin | guanine nucleotide binding protein, alpha 13 | - | - | Pubmed |
| HPRD | catenin, beta 1, 88kDa | Guanine nucleotide binding protein, alpha 13 | - | - | Pubmed |
| HPRD | Dopamine receptor, D5 | guanine nucleotide binding protein, alpha 13 | - | - | Pubmed |
| HPRD | dopamine receptor D5 | Guanine nucleotide binding protein, alpha 13 | - | - | Pubmed |
| HPRD | Endothelial differentiation gene 3 | guanine nucleotide binding protein, alpha 13 | - | - | Pubmed |
| HPRD | endothelial differentiation, sphingolipid G-protein-coupled receptor, 3 | Guanine nucleotide binding protein, alpha 13 | - | - | Pubmed |
Recent Publications on GNA13: |  |
RGS22, a novel testis-specific regulator of G-protein signaling involved in human and mouse spermiogenesis along with GNA12/13 subunits.
The heterotrimeric G-protein pathway controls numerous cellular processes,... | 7th January, 2009
| Laboratory of Reproductive Medicine, Department of Histology and
| Biol Reprod. 2008 Dec;79(6):1021-9. Epub 2008 Aug 13.
DOI Direct Link |
Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors.
Runt-related transcription factor 2 (Runx2) controls lineage commitment,... | 11th November, 2008
| Department of Cell Biology and Cancer Center, University of Massachusetts
| J Biol Chem. 2008 Oct 10;283(41):27585-97. Epub 2008 Jul 14.
DOI Direct Link |
Expression profiles are different in carbon ion-irradiated normal human fibroblasts and their bystander cells.
Evidence has accumulated that ionizing radiation induces biological... | 21st August, 2008
| RadGenomics Research Group, Research Center for Charged Particle Therapy,
| Mutat Res. 2008 Jul 3;642(1-2):57-67. Epub 2008 May 2.
DOI Direct Link |
Identification and characterization of RHOA-interacting proteins in bovine spermatozoa.
In somatic cells, RHOA mediates actin dynamics through a GNA13-mediated... | 26th March, 2008
| Department of Medicine, Oregon Health & Sciences University and Veterans
| Biol Reprod. 2008 Jan;78(1):184-92. Epub 2007 Oct 10.
DOI Direct Link |
GNA13 results (if any) from reagent suppliers | 
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Gα 13 (A-20) Antibody sc-410
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, GNA13, 10672, 17q24.1, NM_006572 ...
http://www.scbt.com/datasheet-410-galpha-13-a-20-antibody.ht...
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Recombinant Proteins - GenWay Biotech Inc.
GNA13; - SYNTHETIC HUMAN G PROTEIN ALPHA 13 (aa368-377); Guanine nucleotide- binding protein alpha-13 subunit, Recombinant Protein ELISA, Source: N/A ...
http://www.genwaybio.com/all_recombinant_proteins.php?fl=G...
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Gα i/o/t/z (D-15) Antibody sc-12798
Mouse, Gna13, 14674, 11 E1, P27601, N/A. Mouse, Gna14, 14675, 19 A, P30677, N/A. Mouse, Gna15, 14676, 10 C1, P30678, N/A. Mouse, Gnai1, 14677, 5 A3 ...
http://www.scbt.com/datasheet-12798-galpha-i-o-t-z-d-15-anti...
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Gα i/o/t/z (D-15) Antibody sc-12798
Mouse, Gna13, 14674, 11 E1, P27601, 없음. Mouse, Gna14, 14675, 19 A, P30677, 없음. Mouse, Gna15, 14676, 10 C1, P30678 ...
http://www.scbt.com/ko/datasheet-12798-galpha-i-o-t-z-d-15-a...
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