BioPortfolio - CGA - glycoprotein hormones, alpha polypeptide

CGA

Symbol:

CGA

Name(s):

glycoprotein hormones, alpha polypeptide

Type:

protein-coding

Organism:

Homo sapiens

Synonyms:

CG-ALPHA, FSHA, GPHA1, GPHa, HCG, LHA, TSHA

Links:

Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link

Summary of findings

17609437

The studies demonstrate the formation, in vivo dynamics of GPHalpha alpha homodimers, and the pathways of the cellular metabolism of variants of GPHalpha, monoglycosylated GPHalpha and large free GPHalpha.

17690166

Recombinant hCG overcomes in vitro the Trisomy 21 phenotype, allowing cytotrophoblasts to fuse and form a large syncytiotrophoblast.

17143726

The approach of fusing the alpha and beta subunits of human Chorionic Gonadotropin (hCG) to produce a single chain hormone (phCGalphabeta) was used to investigate roles of critical residues of the alpha subunit in hormone receptor interaction.

17261286

characterization of the hourly secretion profile of hCG in early pregnancy after donor artificial insemination

14726442

LH and FSH have a dual effect on the cultured rat preovulatory follicle: an antiapoptotic effect on granulosa cells and a proapoptotic effect on theca-interstitial cells.

17097221

hCGalpha is not derived from heterodimeric glycoprotein hormones suggesting hCG-independent functions of hCGalpha and hCGbeta in male and female fertility.

16950818

The present findings indicate that the concentration of human placental lactogen (hPL) and human chorionic gonadotropin (beta hCG) mRNA is significantly higher in the cellular component of maternal blood samples than in the plasma component.

16007123

Overexpression of HCG alpha is associated with adenoma formation

12920232

induction of alphaGSU gene expression by peptide hormone signaling is coupled directly to the posttranslational status of SF-1

12569177

Expressed in human decidual tissue in patients during tubal pregnancy

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