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CEACAM3


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Symbol:CEACAM3
Name(s):carcinoembryonic antigen-related cell adhesion molecule 3
Type:protein-coding
Organism:Homo sapiens
Synonyms:CD66D, CEA, CGM1, MGC119875, W264, W282
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17878338 killing of bulk NK cultures was inhibited by CEA-expressing cells, suggesting that this putative receptor is an inhibitory receptor
17211733 Increased p53, CEA, and CA 19-9 serum levels are associated with colorectal cancer.
12571236 CEACAM3 has a role in internalizing bacteria to epithelial cells
17413979 Our results suggest that an immunohistochemical panel consisting of TTF-1, CEA, CA-125, and OCT-4 is helpful in distinguishing most pulmonary and ovarian carcinomas with clear cell features.
17071045 Molecular staging of SLN using real-time RT-PCR for early breast cancer could serve as a useful complement to standard clinicopathological risk factors.
14707113 CEACAM3 controls human-specific pathogens by the innate immune system.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDcarcinoembryonic antigen-related cell adhesion molecule 1 isoform 1 precursorcarcinoembryonic antigen-related cell adhesion molecule 3--Pubmed
HPRDcarcinoembryonic antigen-related cell adhesion molecule 3S100 calcium-binding protein A8--Pubmed
HPRDcarcinoembryonic antigen-related cell adhesion molecule 3proto-oncogene tyrosine-protein kinase SRC--Pubmed
HPRDcarcinoembryonic antigen-related cell adhesion molecule 3casein kinase 1, alpha 1-like--Pubmed
HPRDcarcinoembryonic antigen-related cell adhesion molecule 3casein kinase 1, alpha 1-like--Pubmed

Recent Publications on CEACAM3:

Pubmed Logo
Rhinovirus enhances various bacterial adhesions to nasal epithelial cells simultaneously.
OBJECTIVES/HYPOTHESIS: Viral upper respiratory tract infections are often...
6th August, 2009
Department of Otolaryngology, Asan Medical Center, University of Ulsan Laryngoscope. 2009 Jul;119(7):1406-11.
DOI Direct Link
Interdependency of CEACAM-1, -3, -6, and -8 induced human neutrophil adhesion to endothelial cells.
Members of the carcinoembryonic antigen family (CEACAMs) are widely...
10th February, 2009
The Department of Medicine, University of Minnesota Medical School, J Transl Med. 2008 Dec 10;6:78.
DOI Direct Link
Differential cell fates induced by all-trans retinoic acid-treated HL-60 human leukemia cells.
HL-60 human leukemia cells, differentiated into a neutrophil lineage by...
29th October, 2008
Division of Immunology, Beckman Research Institute of the City of Hope, J Leukoc Biol. 2008 Sep;84(3):769-79. Epub 2008 Jun 13.
DOI Direct Link
CEACAM3: an innate immune receptor directed against human-restricted bacterial pathogens.
Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) is an...
25th October, 2008
Lehrstuhl Zellbiologie, Fachbereich Biologie X908, Universitat Konstanz, Int J Med Microbiol. 2008 Oct;298(7-8):553-60. Epub 2008 Jul 7.
DOI Direct Link
Genetic construction, expression, and characterization of a single chain anti-CEA antibody fused to cytosine deaminase from yeast.
We report the genetic construction and expression of a fusion protein...
31st July, 2008
Section of Pharmacogenetics, Drug Resistance and Experimental Int J Oncol. 2008 Jun;32(6):1245-51.

View more research publications.

Patents:

Patents logo
US Patent No.Title
7598080 Diagnostic assay for source of inflammation
7531300 Method of diagnosing breast cancer
7235358 Methods and compositions for diagnosing and monitoring transplant rejection
7026121 Methods and compositions for diagnosing and monitoring transplant rejection
6949629 Methods for purifying selected CEA family member proteins

View more patents.

CEACAM3 results (if any) from reagent suppliers

Google CSE Logo
CEACAM3 siRNA (m) sc-142255
Click here for details. suitable control antibody: contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: CEACAM3 ...
http://www.scbt.com/datasheet-142255-ceacam3-sirna-m.html...

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pan CEACAM antibody [TET2] (ab26283) | Abcam
CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEAC...
http://www.abcam.com/pan-CEACAM-antibody-TET2-ab26283.html...

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CEACAM Antibody / CEACAM Antibodies
CEACAM3 shRNA Plasmid (m): sc-142255-SH. CEACAM3 shRNA (m) Lentiviral Particles: sc-142255-V. CEACAM4 siRNA (h): sc-97236 ...
http://www.scbt.com/table-ceacam.html...

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CD-CY
HPA011041, Anti-CEACAM3 antibody produced in rabbit, affinity isolated antibody, human ... CEACAM3(1084), human, IHC (p), PA, pricing ...
https://www.sigmaaldrich.com/etc/controller/controller-page....

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L1 antibody, L1 [MAC387] Antibody, Mouse Monoclonal Antibody
Subunit: Interacts with CEACAM3 in a calcium-dependent manner. Miscellaneous: Has been shown to bind calcium. Similarity: Belongs to the S-100 family. ...
http://www.genwaybio.com/product_info.php?products_id=193980...

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Pregnancy Specific Glycoprotein 1 antibody [BAP3] (ab26284) | Abcam
It does not cross-react significantly with any of the CEACAM subgroup members of the CEA family (CEACAM 1, CEACAM 3, CEACAM 4, CEACAM5/CEA, CEACAM6, ...
http://www.abcam.com/Pregnancy-Specific-Glycoprotein-1-antib...

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Enzo Life Sciences: Monoclonal Antibody to pan-CEACAM (1,5,6,8 ...
It consists of seven CEACAM (CEACAM1, CEACAM3-CEACAM8) and 11 pregnancy-specific glycoprotein (PSG1-PSG11) members. The CEA family proteins belong to the ...
http://www.enzolifesciences.com/ALX-805-081/monoclonal-antib...

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