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ADCY3


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Gene DB Home
Symbol:ADCY3
Name(s):adenylate cyclase 3
Type:protein-coding
Organism:Homo sapiens
Synonyms:AC3, KIAA0511
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17895882 Observational study of gene-disease association. (HuGE Navigator)
17586501 Fully differentiated human airway epithelial cells in culture are shown to express calcium-stimulated transmembrane adenylyl cyclase (tmAC) isoforms (types 1, 3, and 8) by reverse transcription polymerase chain reaction.
12623444 identified AC3as the predominant AC isoform in human platelets, the activity of which may affect the extent and duration of the net aggregation response by modulating deaggregation
17581954 Establishment of the mature glomerular array in transgenic mice requires adenylyl cyclase 3, a key component of the odorant receptor-mediated cyclic AMP-dependent signaling cascade.
12782409 expression of nodular ADCY6, but not ADCY3, was lower than the expression of both in perinodular tissue, which may be part of the mechanisms occurring in the hyperfunctioning nodules

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDadenylate cyclase 3stomatin-like 3--Pubmed

Recent Publications on ADCY3:

Pubmed Logo
Hydrostatic pressure-dependent changes in cyclic AMP signaling in optic nerve head astrocytes from Caucasian and African American donors.
PURPOSE: Investigate the effect of hydrostatic pressure (HP) on 3',...
29th October, 2009
Department of Ophthalmology, Northwestern University, Feinberg School of Mol Vis. 2009 Aug 20;15:1664-72.
Identification of potential therapeutic targets in hypertension-associated bladder dysfunction.
OBJECTIVE To investigate differential gene expression profiles in the...
20th August, 2009
Department of Urology, Graduate School of Medical Sciences, Kumamoto BJU Int. 2009 Aug 18.
DOI Direct Link
An abnormal gene expression of the beta-adrenergic system contributes to the pathogenesis of cardiomyopathy in cirrhotic rats.
Decreased cardiac contractility and beta-adrenergic responsiveness have...
13th January, 2009
Department of Clinical and Experimental Medicine, University of Padova Hepatology. 2008 Dec;48(6):1913-23.
DOI Direct Link
Difference in physiogenomics between male and female infertility.
Infertility is an important condition in reproductive medicine. According...
21st June, 2008
Wiwanitkit House, Bangkhae, Bangkok, Thailand; Hainan Medical College, Andrologia. 2008 Jun;40(3):158-60.
DOI Direct Link
Signaling pathways for modulation of mouse sperm motility by adenosine and catecholamine agonists.
Capacitation of mammalian sperm, including alterations in flagellar...
18th November, 2005
Department of Physiology and Biophysics, University of Washington, Biol Reprod. 2006 Mar;74(3):492-500. Epub 2005 Nov 16.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7598031 Method for the detection of gene transcripts in blood and uses thereof
7588771 Microorganisms for therapy
7588767 Microorganisms for therapy
7547687 Therapeutic treatment methods
7482334 Therapeutic treatment methods

View more patents.

ADCY3 results (if any) from reagent suppliers

Google CSE Logo
ADCY3 antibody (ab14778) | Abcam
Rabbit polyclonal to ADCY3. The membrane-bound adenylyl cyclases (ACs) represent one of the major families of effector enzymes for G protein-coupled ...
http://www.abcam.com/ADCY3-antibody-ab14778.html...

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A cyclase III (C-20) Antibody sc-588
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, ADCY3, 109, 2p23.3, NM_004036 ...
http://www.scbt.com/datasheet-588-a-cyclase-iii-c-20-antibod...

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S153 SQ 22536 ≥98% (HPLC), solid
ADCY1(107), ADCY2(108), ADCY3(109), ADCY4(196883), ADCY5(111), ADCY6(112), ADCY7 (113), ADCY8(114), ADCY9(115). rat ... Adora1(29290), Adora2a(25369) ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...

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A cyclase (R-32) Antibody sc-1701
Mouse, Adcy3, 104111, 12 A1.1, Q8VHH7, 없음. Mouse, Adcy2, 210044, 13 B3, Q80TL1 , 없음. Mouse, Adcy5, 224129, 16 B3, P84309 ...
http://www.scbt.com/ko/datasheet-1701-a-cyclase-r-32-antibod...

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Signal Transduction Antibodies
PA1-31099 · ACTR1B, Hu, WB, $350.87. PA1-31190 · ADCY2, Rt, Hu, Ms, WB, $535.87. PA1-31191 · ADCY3, Rt, Hu, Ms, Ca, WB, $535.87 ...
http://www.bioreagents.com/products/productLists/productBrow...

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Abcam antibodies and reagents product map
... 5HT2C Receptor proteins and peptides (1) · 5HT5A receptor antibodies (5) · ADA2 beta antibodies (1) · ADCY3 antibodies (1) · ADCY4 antibodies (1) ...
http://www.abcam.com/index.html?cl=2105&pageconfig=productma...

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