Monday November 23 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

UBE2C


Suggest Content
Advertise Here
Gene DB Home
Symbol:UBE2C
Name(s):ubiquitin-conjugating enzyme E2C
Type:protein-coding
Organism:Homo sapiens
Synonyms:UBCH10, dJ447F3.2
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
16106252 UbcH10 overexpression is involved in thyroid cell proliferation and may represent a marker of thyroid anaplastic carcinomas
16772118 results showing aberrations in levels of gene expression and locus copy number of ubiquitin-conjugating enzyme E2C gene (UBE2C) suggest that this gene may play an important role in tumor progression leading to advanced colon cancer with liver metastasis
17354233 Ube2c gene appeared to be associated with hepatocellular carcinoma progression
15208666 UbcH10 plays an important role in tumor development and that its inhibition in combination with agonists of the TRAIL receptor may provide an enhanced therapeutic index
12874022 UbcH10 is highly expressed in various human primary tumors and UbcH10 has an ability to promote cell growth and malignant transformation.
17217624 Transfection of dominant-negative UBE2C into Seg-1 esophageal adenocarcinoma cells decreases proliferation and increased mitotic arrest compared to vector controls.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDUbiquitin conjugating enzyme E2Canaphase-promoting complex subunit 2--Pubmed
HPRDubiquitin-conjugating enzyme E2C isoform 1Anaphase promoting complex subunit 2--Pubmed
HPRDubiquitin-conjugating enzyme E2C isoform 1ubiquitin-conjugating enzyme E2C isoform 1--Pubmed

Recent Publications on UBE2C:

Pubmed Logo
Microarray gene expression profiling in meningiomas: Differential expression according to grade or histopathological subtype.
Meningiomas, one of the largest subgroup of intracranial tumours are...
4th November, 2009
INSERM U842, Faculte de Medecine RTH Laennec, 69372 Lyon cedex 08, France. Int J Oncol. 2009 Dec;35(6):1395-1407.
Microarray analysis identifies differentially expressed genes induced by human papillomavirus type 18 E6 silencing RNA.
The oncoprotein E6 of high-risk human papillomavirus (HPV) types promotes...
26th September, 2009
Institute of Molecular Biology, Southern Medical University, Guangzhou, Int J Gynecol Cancer. 2009 May;19(4):547-63.
DOI Direct Link
Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer.
The evolution of prostate cancer from an androgen-dependent state to one...
18th August, 2009
Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Cell. 2009 Jul 23;138(2):245-56.
DOI Direct Link
UbcH10 expression in human lymphomas.
AIMS: The UbcH10 ubiquitin-conjugating enzyme plays a key role in...
6th August, 2009
Dipartimento di Scienze Biomorfologiche e Funzionali, University of Naples Histopathology. 2009 May;54(6):731-40.
DOI Direct Link
Identification of gene signatures and molecular markers for human lung cancer prognosis using an in vitro lung carcinogenesis system.
Lung cancer continues to be a major deadly malignancy. The mortality of...
30th July, 2009
Departments of Thoracic/Head and Neck MedicalOncology, M. D. Anderson Cancer Prev Res (Phila Pa). 2009 Aug;2(8):702-11. Epub 2009 Jul 28.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7608395 Systemic lupus erythematosus diagnostic assay
6538126 Hepatitis C diagnostics and vaccines
6919184 Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents
6979551 Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents
7132234 Methods and compositions for the identification of anti-poxvirus agents

View more patents.

UBE2C results (if any) from reagent suppliers

Google CSE Logo
UBE2C antibody (ab56861) | Abcam
Mouse monoclonal to UBE2C. UBE2C catalyzes the covalent attachment of ubiquitin to other proteins. It is required for the destruction of mitotic cyclins.
http://www.abcam.com/UBE2C-antibody-ab56861.html...

Thumbshot
UBE2C (19R) Antibody sc-100611
Western blot analysis of UBE2C expression in human UBE2C transfected: sc-111903 (A) and ... UBE2C (19R): sc-100611. Immunofluorescence staining of ...
http://www.scbt.com/datasheet-100611-UBE2C-19r-antibody.html...

Thumbshot
Anti-UBE2C Polyclonal Antibody
Polyclonal Antibody against UBE2C for use in Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...

Thumbshot
UBE2C monoclonal antibody (M04)
UBE2C (AAH50736, 1 a.a. ~ 180 a.a) full length recombinant protein with GST tag. ... Western Blot analysis of UBE2C expression in transfected 293T cell line ...
http://www.abgent.com/products/catalog_no/AT4430a_UBE2C_mono...

Thumbshot
UBE2C (h2): 293T Lysate sc-116349
100 µg protein in 200 µl SDS-PAGE buffer; suitable as Western Blotting control for UBE2C antibodies; human UBE2C transfected 293T lysate; suitable control ...
http://www.scbt.com/datasheet-116349-UBE2C-h2-293t-lysate.ht...

Thumbshot
Ubiquitin (Ub) is a 76 amino acid highly conserved eukaryotic ...
UBE2C C-term Antibody. AP2158a. UEV N-term Antibody. AP2149a. USP24 N-term Antibody ... UBE2C N-term Antibody. AP2130b. USP1 N-term Antibody. AP2150a ...
http://www.abgent.com/downloads/Ubiquitination.pdf...

Thumbshot
UBE2C (B-12) Antibody sc-166339
UBE2C (B-12): sc-166339. Western blot analysis of UBE2C expression in non- transfected: sc-117752 (A) and human UBE2C transfected: sc-116349 (B) 293T whole
...
http://www.scbt.com/ko/datasheet-166339-ube2c-b-12-antibody....

Thumbshot

Search Bioportfolio and other Life Science Sites for UBE2C, or search for UBE2C on BioPortfolio's antibody search engine.
This page has been viewed 94 times
Recent Search Terms used to find this page:
uPAR antibody, rat, IHC (P) | UBE2C CELL CYCLE | UBE2C and cancer | ube2c | ube2c | .


Resources from the NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.