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ADAMTS13
| Symbol: | ADAMTS13 | | Name(s): | ADAM metallopeptidase with thrombospondin type 1 motif, 13 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | C9orf8, DKFZp434C2322, FLJ42993, MGC118899, MGC118900, TTP, VWFCP, vWF-CP | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18223285 |
Survivors of an acute episode of acquired thrombotic thrombocytopenic purpura with severely reduced levels of ADAMTS13 and/or with anti-ADAMTS13 antibodies during remission have |
| 17928530 |
provided visual evidence for a shear rate-dependent action of ADAMTS13 that limits thrombus growth directly at the site of the ongoing thrombus generation process |
| 17901248 |
ADAMTS13 preferentially acts on platelet-VWF complexes under fluid shear stress |
| 15182579 |
Observational study of gene-disease association. (HuGE Navigator) |
| 16990571 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18031293 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17922807 |
Specific to the type 2B VWD group was an increase in the percentage of high molecular weight VWF multimers, a decrease in the mean platelet count, and an increase in the ADAMTS-13 level |
| 18175284 |
ADAMTS-13 levels in multisystem thrombotic microangiopathy and other pathologic conditions [review] |
| 17988227 |
ADAMTS13 MUTATIONS IN THE FAMILY OF A Upshaw-Schulman syndrome PATIENTS |
| 17764538 |
VWF parameters are reciprocally correlated with ADAMTS-13 activity in severe sepsis and septic shock but have no prognostic value regarding outcome | →View more information from publications. |
Recent Publications on ADAMTS13: |  |
Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor.
ADAMTS13 specifically cleaves plasma von Willebrand factor (VWF) and... | 3rd November, 2009
| National Cardiovascular Center Research Institute, Suita, Osaka 565-8565,
| Proc Natl Acad Sci U S A. 2009 Oct 30.
DOI Direct Link |
Current insight into thrombotic thrombocytopenic purpura.
During the last three decades knowledge regarding the pathophysiology of... | 24th October, 2009
| aUniversity Hospitals Gasthuisberg, Department of Internal Medicine,
| Blood Coagul Fibrinolysis. 2009 Oct 21.
DOI Direct Link |
ADAMTS13 mutations and polymorphisms in congenital thrombotic thrombocytopenic purpura.
Congenital thrombotic thrombocytopenic purpura (TTP) (also known as... | 23rd October, 2009
| Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Universita degli
| Hum Mutat. 2009 Oct 21.
DOI Direct Link |
Refractory thrombotic thrombocytopenic purpura associated with oral contraceptives and factor V Leiden: a case report.
INTRODUCTION: Thrombotic microangiopathies constitute a heterogeneous... | 16th October, 2009
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| Cases J. 2009 May 12;2:6611.
DOI Direct Link |
Endothelial cell ADAMTS-13 and VWF: production, release and VWF string cleavage.
Human umbilical vein endothelial cell (HUVEC)-released ADAMTS-13 and... | 14th October, 2009
| Rice University, United States;
| Blood. 2009 Oct 12.
DOI Direct Link |
→View more research publications. |
ADAMTS13 results (if any) from reagent suppliers | 
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ADAMTS13 antibody - Metalloproteinase domain (ab28274) | Abcam
Rabbit polyclonal to ADAMTS13 - Metalloproteinase domain. ADAMTS13, also known as von Willebrands factor cleaving protease (vWFcp), was first identified by ...
http://www.abcam.com/ADAMTS13-antibody-Metalloproteinase-dom...
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ADAMTS13 Antibody (Center)
Western blot analysis of anti-ADAMTS13 Antibody (Center)(Cat.#AP7438c) in CEM cell line lysates ... ADAMTS13 (arrow) was detected using the purified Pab. ...
http://www.abgent.com/products/catalog_no/AP7438c_ADAMTS13_A...
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ADAMTS13 antibody - Carboxyterminal end long isoform (ab28273) | Abcam
Rabbit polyclonal to ADAMTS13 - Carboxyterminal end long isoform. ADAMTS13, also known as von Willebrands factor cleaving protease (vWFcp), ...
http://www.abcam.com/ADAMTS13-antibody-Carboxyterminal-end-l...
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ADAMTS Antibody / ADAMTS Antibodies
ADAMTS-13 (C-17) Antibody, sc-21511, goat IgG, C-terminus (h), WB, IF, ... ADAMTS-13 (C7) Antibody, sc-101395, mouse IgG1, FL (h), WB, IF, ELISA, human ...
http://www.scbt.com/table-adamts.html...
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ADAMTS13 antibody (ab72075) | Abcam
Rabbit polyclonal to ADAMTS13. ADAMTS13, also known as von Willebrands factor cleaving protease (vWFcp), was first identified by its ability to cleave the ...
http://www.abcam.com/ADAMTS13-antibody-ab72075.html...
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monoclonal antibody template
von Willebrand Factor A2 Domain (ADAMTS13-cleaved) Antibody ... domain with ADAMTS13. It does not detect intact rhvWF-A2 domain. Application ...
http://www.rndsystems.com/pdf/MAB27642.pdf...
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BIOMOL International - Anti-ADAMTS13
Immunogen: peptide based on the catalytic domain of human ADAMTS13 (von Willebrand factor-cleaving enzyme). Supplied as affinity-purified rabbit ...
http://www.biomol.com/Online_Catalog/Online_Catalog/Products...
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