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ADAMTS8
| Symbol: | ADAMTS8 | | Name(s): | ADAM metallopeptidase with thrombospondin type 1 motif, 8 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | ADAM-TS8, FLJ41712, METH2 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17606262 |
ADAMTS-4 and -8 are inflammatory regulated enzymes expressed in macrophage-rich areas of atherosclerotic plaques |
| 15328519 |
Downdownregulation of METH-2 expression in primary NSCLC, often associated with promoter hypermethylation, is a frequent event, which may be related to the development of the disease. |
| 16570050 |
Immunohistochemistry and Western analysis indicated downregulation of ADAMTS-8 protein in >77% brain tumours. A role for ADAMTS-8 in brain tumorigenesis, warranting further investigation into its role in regulation of tumour angiogenesis. |
| 16152618 |
ADAMTS8 and ADAMTS15 have emerged as novel predictors of survival in patients with breast carcinoma |
| 15296936 |
Ability of ADAMTS-8 to cleave aggrecan at aggrecanase-susceptible Glu373-Ala374 peptide bond. Presence of ADAMTS-8 mRNA transcripts in normal and osteoarthritic human cartilage. (ADAMTS-8) |
Recent Publications on ADAMTS8: |  |
ADAMTS-4 and -8 are inflammatory regulated enzymes expressed in macrophage-rich areas of human atherosclerotic plaques.
OBJECTIVES: Remodeling of extracellular matrix (ECM) plays an important... | 25th March, 2008
| Atherosclerosis Research Unit, King Gustav V Research Institute,
| Atherosclerosis. 2008 Feb;196(2):514-22. Epub 2007 Jul 2.
DOI Direct Link |
The quantification of ADAMTS expression in an animal model of cerebral ischemia using real-time PCR.
BACKGROUND: ADAMTS1 and ADAMTS8 are proteases involved in extracellular... | 10th April, 2007
| Institute of Neurobiology, Key Laboratory of Environment and Genes Related
| Acta Anaesthesiol Scand. 2007 Feb;51(2):158-64. Epub 2006 Nov 1.
DOI Direct Link |
Expression of ADAMTS-8, a secreted protease with antiangiogenic properties, is downregulated in brain tumours.
Angiogenesis and extracellular matrix degradation are key events in tumour... | 12th September, 2006
| JK Douglas Cancer Research Laboratories, Clatterbridge Hospital,
| Br J Cancer. 2006 Apr 24;94(8):1186-93.
DOI Direct Link |
ADAMTS8 and ADAMTS15 expression predicts survival in human breast carcinoma.
We recently undertook expression profiling of all 19 human ADAMTS... | 3rd March, 2006
| School of Biological Sciences, University of East Anglia, Norwich, United
| Int J Cancer. 2006 Mar 1;118(5):1241-7.
DOI Direct Link |
ECM1 and TMPRSS4 are diagnostic markers of malignant thyroid neoplasms and improve the accuracy of fine needle aspiration biopsy.
OBJECTIVE: The objective of this study was to determine whether genes that... | 12th October, 2005
| Endocrine Surgery and Oncology Program, Comprehensive Cancer Center,
| Ann Surg. 2005 Sep;242(3):353-61; discussion 361-3.
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→View more research publications. |
ADAMTS8 results (if any) from reagent suppliers | 
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ADAMTS8 peptide (Amino end of propeptide domain) (ab45241) | Abcam
ADAMTS8 peptide (Amino end of propeptide domain). ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type.
http://www.abcam.com/ADAMTS8-peptide-Amino-end-of-propeptide...
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ADAMTS Antibody / ADAMTS Antibodies
ADAMTS-8 (Q-14) Antibody, sc-21498, goat IgG, C-terminus (h), WB, IF, ... ADAMTS -8 (H-17) Antibody, sc-5472, goat IgG, internal (h), WB, IF, ELISA, m, r, h ...
http://www.scbt.com/table-adamts.html...
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ADAMTS8 proteins and peptides: Cancer > Invasion/microenvironment ...
ADAMTS8 proteins and peptides. ... ADAMTS8 peptide (Amino end of propeptide domain). WB, ELISA ... ADAMTS8 peptide (Carboxyterminal end). WB, ELISA ...
http://www.abcam.com/index.html?t=136514&pt=2&c=4261&ei=&mu=...
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ADAMTS-8 siRNA (h) sc-43603
Click here for details. suitable control antibody: ADAMTS-8 (C-16): sc-21499; sqRT-PCR Primer also available: ADAMTS-8 (h)-PR: sc-43603-PR, 20 µl ...
http://www.scbt.com/ko/datasheet-43603-adamts-8-sirna-h.html...
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Abgent - Cell and Function Antibodies
AP7447cNEW, ADAMTS5 Antibody (Center), WB, E, H, M. AT1050a, ADAMTS8 monoclonal antibody (M01), ELISA,S-ELISA,WB-Re, H. AP8177a, ADCK1 Antibody (N-term) ...
http://www.abgent.com/products/category/cell_function...
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ADAMTS-8 siRNA (m) sc-45834
Click here for details. contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: ADAMTS-8 (m)-PR: sc-45834-PR, 20 µl
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http://www.scbt.com/ja/datasheet-45834-adamts-8-sirna-m.html...
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ADAMs - R&D Systems
... organ morphology and function based on knockout mice.71 ADAMTS1 (METH1) and ADAMTS8 (METH2) suppress FGF-2-induced vascularization in the cornea pocket ...
http://www.rndsystems.com/mini_review_detail_objectname_MR01...
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