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AKAP13
| Symbol: | AKAP13 | | Name(s): | A kinase (PRKA) anchor protein 13 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | AKAP-Lbc, BRX, FLJ11952, FLJ43341, HA-3, Ht31, LBC, PROTO-LB, PROTO-LBC, c-lbc | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 16234258 |
Observational study of gene-disease association. (HuGE Navigator) |
| 16956908 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18093280 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17878165 |
AKAP13 plays a role in TLR2-mediated NF-kappaB activation; GEF-containing scaffold proteins may confer specificity to innate immune responses downstream of TLRs |
| 12663445 |
The HA-3 peptide, VTEPGTAQY, is encoded by the lymphoid blast crisis oncogene, showing for the 1st time that a leukemia-associated oncogene can give rise to immunogenic T-cell epitopes that may participate in antihost & antileukemic alloimmune responses. |
| 14660653 |
results indicate that guanine nucleotide exchange factor Lbc is a novel signal transducer for RhoA-mediated NF-kappaB activation in human peripheral blood monocytes stimulated with bacterial products |
| 14636890 |
Proto-Lbc mutant expression led to decreased levels of Galpha12-induced RhoA activation in vivo. |
| 12270917 |
Results show that alpha-catulin co-expression leads to increased Lbc-induced serum response factor activation and may modulate Rho pathway signaling in vivo by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor. |
| 15229649 |
Anchoring of both PKA and 14-3-3 inhibits the Rho-GEF activity of the AKAP-Lbc signaling complex. |
| 16301118 |
Yeast 2-Hybrid experiments identified a strong and novel interaction between the transglutaminase moiety and protein kinase A anchor protein 13 (AKAP13) | →View more information from publications. |
Recent Publications on AKAP13: |  |
The mRNA and protein expression of A-kinase anchor proteins 13 in human colorectal cancer.
There was no literature reporting the relationship between AKAP13 and... | 26th September, 2009
| Department of General Surgery & Institute of Digestive Surgery and State
| Clin Exp Med. 2009 Sep 25.
DOI Direct Link |
Characterization of human gene expression changes after olive oil ingestion: an exploratory approach.
Olive oil consumption is protective against risk factors for... | 26th August, 2009
| Cardiovascular Risk and Nutrition Research Group, Institut Municipal d
| Folia Biol (Praha). 2009;55(3):85-91.
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Brx shines a light on the route from hyperosmolarity to NFAT5.
Nuclear factor of activated T cells 5 (NFAT5) is a member of the Rel... | 2nd June, 2009
| Immunology Unit, Department of Experimental and Health Sciences,
| Sci Signal. 2009 Apr 7;2(65):pe20.
DOI Direct Link |
Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature.
Here we used the Met-1 cell line in an orthotopic transplantation model in... | 20th May, 2009
| Department of Cancer Biology, Kimmel Cancer Center, Thomas Jefferson
| Am J Pathol. 2009 May;174(5):1650-62.
DOI Direct Link |
Brx mediates the response of lymphocytes to osmotic stress through the activation of NFAT5.
Extracellular hyperosmolarity, or osmotic stress, generally caused by... | 16th May, 2009
| Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver
| Sci Signal. 2009 Feb 10;2(57):ra5.
DOI Direct Link |
→View more research publications. |
AKAP13 results (if any) from reagent suppliers | 
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AKAP13 antibody (ab56916) | Abcam
Mouse monoclonal to AKAP13. AKAP13 functions as a protein kinase A (PKA)- anchoring protein and acts as an adapter protein to selectively couple G alpha-
13 ...
http://www.abcam.com/AKAP13-antibody-ab56916.html...
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AKAP13/AKAP-Lbc Antibody Bethyl Laboratories
Rabbit anti-AKAP13/AKAP-Lbc Antibody, Affinity Purified.
http://www.bethyl.com/go/?product/A301-403A...
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AKAP 13 (ZX-18) Antibody sc-81902
mouse monoclonal IgG2a, 50 µg/0.5 ml; raised against recombinant AKAP 13 of human origin ... AKAP 13 (ZX-18): sc-81902. Immunofluorescence staining of ...
http://www.scbt.com/datasheet-81902-akap-13-zx-18-antibody.h...
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AKAP13 antibodies: Cardiovascular > Heart > Hypertrophy > Other ...
AKAP13 antibodies. ... AKAP13 antibody. IHC-P, WB, ELISA. Images. Rabbit polyclonal. Reacts with: Hu. Terms and conditions · Legal · Privacy policy ...
http://www.abcam.com/index.html?t=230943&pt=1&c=4453&ei=&mu=...
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AKAP 13 (N-19) Antibody sc-9335
goat polyclonal IgG, 200 µg/ml; epitope mapping near the N-terminus of AKAP 13 of human origin; recommended for detection of Lbc and Brx of human origin by ...
http://www.scbt.com/datasheet-9335-AKAP-13-n-19-antibody.htm...
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Abgent - Cell and Function Antibodies
AT1084a, AKAP13 monoclonal antibody (M01), ELISA,IF,S-ELISA,WB-Re, H. AT1085a, AKAP13 monoclonal antibody (M10), ELISA,IHC-P,S-ELISA,WB-Ce,WB-Re, H ...
http://www.abgent.com/products/category/cell_function...
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AKAP 13 siRNA (h) sc-41721
Click here for details. suitable control antibody: AKAP 13 (R-19): sc-9336; sqRT -PCR Primer also available: Lbc (h)-PR: sc-41721-PR, 20 µl ...
http://www.scbt.com/datasheet-41721-AKAP-13-sirna-h.html...
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