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PADI2


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Symbol:PADI2
Name(s):peptidyl arginine deiminase, type II
Type:protein-coding
Organism:Homo sapiens
Synonyms:KIAA0994, PAD-H19, PAD2, PDI2
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17968929 PAD-2 & PAD-4 are only isotypes expressed in synovial tissue in rheumatoid arthritis & other arthritides; inflammatory cells are major source, but PAD-4 also comes from hyperplastic synoviocytes; both isotypes probably involved in citrullination of fibrin
17469138 The amount of peptidyl arginine deiminase type II enzyme and citrullinated myelin basic protein was increased in multiple sclerosis
12392711 molecular cloning and gene organization; expressed by all the living epidermal layers, suggesting that PAD type II is functionally important during terminal differentiation of epidermal keratinocytes
15629448 hPADI2 and hPADI4 have different roles under physiological and pathological conditions
15555572 first report to demonstrate a measurable response in the amounts of peptidylarginine deiminase type II mRNA, protein and activity in human astrocytes by prolonged hypoxic exposure

Recent Publications on PADI2:

Pubmed Logo
Peptidylarginine deiminase gene is differentially expressed in freshwater and brackish water rainbow trout.
Peptidylarginine deiminase (PADI)-like cDNA sequence was isolated from...
21st August, 2009
Forschungsinstitut fur die Biologie landwirtschaftlicher Nutztiere (FBN), Mol Biol Rep. 2009 Aug 20.
DOI Direct Link
A two-stage case-control association study of PADI2 with schizophrenia.
Peptidylarginine deiminases (PADIs), five isoforms of which have been...
30th May, 2009
Department of Psychiatry, Niigata University Graduate School of Medical J Hum Genet. 2009 Jul;54(7):430-2. Epub 2009 May 29.
DOI Direct Link
Transcriptional regulation of peptidylarginine deiminase expression in human keratinocytes.
Peptidylarginine deiminase (PAD, EC 3.5.3.15) enzyme catalyzes the...
6th March, 2009
Department of Applied Biological Resource Sciences, School of Agriculture, J Dermatol Sci. 2009 Jan;53(1):2-9. Epub 2008 Nov 11.
DOI Direct Link
Regulation of the expression of peptidylarginine deiminase type II gene (PADI2) in human keratinocytes involves Sp1 and Sp3 transcription factors.
Peptidylarginine deiminases (PAD) convert protein-bound arginine residues...
3rd June, 2005
Department of Applied Biological Resource Sciences, School of Agriculture, J Invest Dermatol. 2005 May;124(5):1026-33.
DOI Direct Link
Comparison of enzymatic properties between hPADI2 and hPADI4.
In the sera of rheumatoid arthritis (RA) patients, autoantibodies directed...
12th March, 2005
Sankyo Co., Ltd., 1-2-58 Hiromachi, Shinagawa-ku, Tokyo 140-8710, Japan. Biochem Biophys Res Commun. 2005 Feb 4;327(1):192-200.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7611839 Methods for diagnosing RCC and other solid tumors
7598080 Diagnostic assay for source of inflammation
7585634 Method of predicting risk of lung cancer recurrence, and a composition, kit and microarray for the same

PADI2 results (if any) from reagent suppliers

Google CSE Logo
PADI2 / PAD2 antibody (ab56928) | Abcam
Mouse monoclonal to PADI2 / PAD2. PADI2 / PAD2 is a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post translational ...
http://www.abcam.com/PADI2-PAD2-antibody-ab56928.html...

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PADI Antibody / PADI Antibodies
PADI2 (Z-22) Antibody, sc-133877, rabbit IgG, N/A, WB, IP, ELISA, human ... PADI2 shRNA Plasmid (h): sc-61281-SH. PADI2 shRNA (h) ...
http://www.scbt.com/table-padi.html...

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PADI2 / PAD2 antibodies: Chromatin and Nuclear Signaling ...
PADI2 / PAD2 antibodies. ... PADI2 / PAD2 antibody. Flow Cyt, WB, ELISA, ICC/IF, IHC-P ... PADI2 / PAD2 antibody. Flow Cyt, WB, IHC-P. Rabbit polyclonal ...
http://www.abcam.com/index.html?t=97881&pt=1&c=4170&ei=&mu=r...

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PADI2 Recombinant Human Peptidyl Arginine Deiminase Type II His-Tagged
Recombinant human PADI2 His-tagged is intended for studies on its deimination ... Recommended PAD concentration: 12.5 mU PADI2 in 100 µl deimination buffer
...
http://www.cellsciences.com/PDF/MON9107.pdf...

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PADI2 siRNA (m) sc-61282
Click here for details. contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: PADI2 (m)-PR: sc-61282-PR, 20 µl ...
http://www.scbt.com/ko/datasheet-61282-padi2-sirna-m.html...

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Abgent - Translation and Regulation Antibodies ...
AT3168aNEW, PADI2 monoclonal antibody (M01), ELISA,S-ELISA,WB-Re, H. AT3208aNEW, PCBP2 monoclonal antibody (M02), ELISA,WB-Ce, H ...
http://www.abgent.com/products/category/nuclear_signaling/tr...

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PADI2 (Z-22) Antibody sc-133877
rabbit polyclonal IgG, 50 µg/0.5 ml; recommended for detection of PADI2 of human ... Western blot analysis of PADI2 expression in Jurkat whole cell lysate. ...
http://www.scbt.com/ko/datasheet-133877-padi2-z-22-antibody....

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