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PACSIN2


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Symbol:PACSIN2
Name(s):protein kinase C and casein kinase substrate in neurons 2
Type:protein-coding
Organism:Homo sapiens
Synonyms:SDPII
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
16551695 Thus, syndapin-dynamin complexes are crucial and sufficient to promote vesicle formation from the trans-Golgi network.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDFAS ligandprotein kinase C and casein kinase substrate in neurons 2--Pubmed
HPRDfas ligandPACSIN2--Pubmed
BINDfas ligandprotein kinase C and casein kinase substrate in neurons 2CD95L interacts with PACSIN2.-Pubmed
HPRDPACSIN2protein kinase C and casein kinase substrate in neurons 3--Pubmed
HPRDprotein kinase C and casein kinase substrate in neurons 2PACSIN3--Pubmed

Recent Publications on PACSIN2:

Pubmed Logo
Molecular mechanism of membrane constriction and tubulation mediated by the F-BAR protein Pacsin/Syndapin.
Peripheral membrane proteins of the Bin/amphiphysin/Rvs (BAR) and Fer-CIP4...
27th August, 2009
Department of Molecular Medicine, College of Veterinary Medicine, Cornell Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12700-5. Epub 2009 Jun 19.
DOI Direct Link
Gene expression profiles following exposure to a developmental neurotoxicant, Aroclor 1254: pathway analysis for possible mode(s) of action.
Epidemiological studies indicate that low levels of polychlorinated...
25th September, 2008
Cellular and Molecular Toxicology Branch, Neurotoxicology Division, Toxicol Appl Pharmacol. 2008 Sep 1;231(2):179-96. Epub 2008 May 6.
DOI Direct Link
PACSIN proteins bind tubulin and promote microtubule assembly.
PACSINs are intracellular adapter proteins involved in vesicle transport,...
24th July, 2008
Center for Biochemistry, Medical Faculty, University of Cologne, Exp Cell Res. 2008 Jun 10;314(10):1991-2003. Epub 2008 Mar 29.
DOI Direct Link
PACSIN2 regulates cell adhesion during gastrulation in Xenopus laevis.
We previously identified the adaptor protein PACSIN2 as a negative...
17th July, 2008
Department of Veterinary and Animal Sciences, University of Massachusetts, Dev Biol. 2008 Jul 1;319(1):86-99. Epub 2008 May 21.
DOI Direct Link
A proteomic screen reveals novel Fas ligand interacting proteins within nervous system Schwann cells.
Fas ligand (FasL) binds Fas (CD95) to induce apoptosis or activate other...
8th January, 2008
Department of Physiology, McGill University, 3655 Promenade Sir William FEBS Lett. 2007 Sep 18;581(23):4455-62. Epub 2007 Aug 22.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7595159 Prediction of Parkinson's disease using gene expression levels of peripheral blood samples
7547687 Therapeutic treatment methods
7482334 Therapeutic treatment methods
7250496 Bioinformatically detectable group of novel regulatory genes and uses thereof
7202329 Tsg101-GAGp6 interaction and use thereof

View more patents.

PACSIN2 results (if any) from reagent suppliers

Google CSE Logo
Anti-PACSIN 2 Polyclonal Antibody
Polyclonal Antibody against PACSIN 2 for use in Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...

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PACSIN2 siRNA (h) sc-36173
Click here for details. suitable control antibody: PACSIN2 (M-19): sc-10417; sqRT-PCR Primer also available: PACSIN2 (h)-PR: sc-36173-PR, 20 µl ...
http://www.scbt.com/datasheet-36173-pacsin2-sirna-h.html...

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Filamin A antibody (ab11074) | Abcam
PACSIN2 regulates cell adhesion during gastrulation in Xenopus laevis. Dev Biol 319:86-99 (2008). ICC/IF, IP; Xenopus laevis. PubMed: 18495106 ...
http://www.abcam.com/Filamin-A-antibody-ab11074.html...

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PACSIN Antibody / PACSIN Antibodies
PACSIN2 (M-19) Antibody, sc-10417, goat IgG, C-terminus (m), WB, IP, IF, ELISA ... PACSIN2 (K-16) Antibody, sc-10415, goat IgG, internal (m), ELISA, m, r, h
...
http://www.scbt.com/table-pacsin.html...

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Protein phosphorylation is one of the most significant signal ...
PACSIN2. PI3KC2A. PPNK. SGK. TRRAP. ALS2CR7. CDC7L1. CRK7. EPHA6. GALK2. ILK1. MAPK10. MSK1. PACSIN3. PI3KC2B. PRK2. SGK2. TSSK1. AMPK1. CDK1. CSF1R. EPHA7 ...
http://www.abgent.com/downloads/Kinases.pdf...

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Abcam antibodies and reagents product map
... PACSIN1 antibodies (2) · PACSIN1 proteins and peptides (1) · PACSIN2 antibodies (1) · PAMCI antibodies (1) · PAMCI proteins and peptides (1) ...
http://www.abcam.com/index.html?c=2105...

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Abgent - Phosphorylation Antibodies - Phosphorylation
AP8087a, PACSIN1 Antibody (N-term), WB, IHC, E, H, M. AP8088b, PACSIN2 Antibody (C-term), WB, IF, IHC, E, H, M. AP8088c, PACSIN2 Antibody (Center), WB, E, H ...
http://www.abgent.com/products/category/protein_modification...

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