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XPOT


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Gene DB Home
Symbol:XPOT
Name(s):exportin, tRNA (nuclear export receptor for tRNAs)
Type:protein-coding
Organism:Homo sapiens
Synonyms:XPO3
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17224653 Exportin-t preferentially binds and exports those tRNAs that are rapidly consumed by the protein synthesis machinery.
16707848 Results suggest that decreased expression of exportin-1 and exportin-t induced by 1alpha,25-dihydroxyvitamin D3 can be correlated to inhibition of the proliferation of HL-60 cells.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDhigh density lipoprotein binding proteintRNA exportin--Pubmed
HPRDhigh density lipoprotein binding proteintRNA exportin--Pubmed
HPRDras-related nuclear proteintRNA exportin--Pubmed
HPRDras-related nuclear proteintRNA exportin--Pubmed
HPRDRan binding protein 2tRNA exportin--Pubmed
HPRDRAN binding protein 2Exportin-T--Pubmed
HPRDNUP214tRNA exportin--Pubmed
HPRDnucleoporin 214kDaExportin-T--Pubmed
HPRDNUP153tRNA exportin--Pubmed
HPRDnucleoporin 153kDaExportin-T--Pubmed

Recent Publications on XPOT:

Pubmed Logo
Structures of the tRNA export factor in the nuclear and cytosolic states.
Transfer RNAs are among the most ubiquitous molecules in cells, central to...
2nd October, 2009
Structural Cell Biology, MPI for Biochemistry, Am Klopferspitz 18, 82152 Nature. 2009 Sep 3;461(7260):60-5.
DOI Direct Link
Interaction of immobilized human exportin-t with calf liver tRNA.
The binding of tRNA species from calf liver to immobilized exportin-t in...
12th May, 2007
Laboratorium fur Biochemie, Universitat Bayreuth, Bayreuth, Germany. RNA Biol. 2006 Oct;3(4):145-9. Epub 2006 Oct 9.
1,25-Dihydroxyvitamin D3 suppresses exportin expression in human promyelocytic leukemia HL-60 cells.
The active form of vitamin D3, 1alpha,25-dihydroxyvitamin D3 (DVD), is a...
18th July, 2006
Laboratory of Cellular Biochemistry, Graduate School of Nutritional and Biomed Res. 2006 Apr;27(2):89-92.
Nuclear export of RNA.
A defining feature of eukaryotic cells is the presence of a nuclear...
27th April, 2005
Institut Jacques Monod, UMR 7592, CNRS, Universites Paris VI and VII, 2 Biol Cell. 2004 Oct;96(8):639-55.
DOI Direct Link
Nuclear export of microRNA precursors.
MicroRNAs (miRNAs), which function as regulators of gene expression in...
30th January, 2004
Department of Biomolecular Chemistry, University of Wisconsin Medical Science. 2004 Jan 2;303(5654):95-8. Epub 2003 Nov 20.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7608395 Systemic lupus erythematosus diagnostic assay
7235358 Methods and compositions for diagnosing and monitoring transplant rejection
7026121 Methods and compositions for diagnosing and monitoring transplant rejection
6905827 Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
4886941 Circuit for interfacing mouse input device to computer system

View more patents.

XPOT results (if any) from reagent suppliers

Google CSE Logo
Anti-XPOT Polyclonal Antibody
Polyclonal Antibody against XPOT for use in Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...

Thumbshot
Exportin T (3236C1a) Antibody sc-81269
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, XPOT, 11260, 12q14.2, NM_007235 ...
http://www.scbt.com/datasheet-81269-exportin-t-3236c1a-antib...

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Abgent - Cancer Antibodies - Cancer
AP6684bNEW, XPO1 Antibody (C-term), WB, E, H, M. AP6688bNEW, XPO6 Antibody (C- term), WB, E, H. AP7632bNEW, XPOT Antibody (C-term), WB, E, H ...
http://www.abgent.com/products/category/cell_function/cancer...

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Exportin T (C-20) Antibody sc-25112
Humain, XPOT, 11260, 12q14.2, NM_007235 · O43592 · 603180. Souris, Xpot, 73192, 10 D2, Q9CRT8, Non disponible. Produits disponibles ...
http://www.scbt.com/fr/datasheet-25112-exportin-t-c-20-antib...

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Exportin T (C-20) Antibody sc-25112
Species, Nome del gene, Codice del gene, Locus cromosoma, Isoform (mRNA) Accession #, codice accesso proteina, Numero d' ordine. Human, XPOT, 11260,
12q14.2 ...
http://www.scbt.com/it/datasheet-25112-exportin-t-c-20-antib...

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Exportin Antibody / Exportin Antibodies
제품명, 카탈로그 번호, ISOTYPE, EPITOPE, APPLICATIONS, SPECIES. Exportin 4 (A-16 ) Antibody, sc-13422, goat IgG, N-terminus (m), WB, IF, ELISA, m, r, h ...
http://www.scbt.com/ko/table-exportin.html...

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