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CHRM1
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18073210 |
M1 muscarinic and alpha7 nicotinic receptors have roles in inhibition of pemphigus acantholysis |
| 14504414 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15383745 |
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) |
| 16874522 |
Observational study of gene-disease association. (HuGE Navigator) |
| 16931638 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17373692 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17655760 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17540859 |
The observations suggest that Cysteine pairs Cys259/Cys260 and Cys262/Cys263 in the 3rd intracellular loop play an important role in the agonist-induced internalization of muscarinic M1 receptors. |
| 16336219 |
Increased phosphorylation of M1 and M2 mAChRs underlies sequestration of these receptors after transient hypoxia. Distinct pathways involving CK1alpha and GRK2 mediated sequestration of M1 and M2 mAChRs after transient hypoxic-induced oxidative stress. |
| 12049494 |
Fifteen single nucleotide polymorphisms (SNPs) of CHRM1 have been discovered, 9 of which are located in the coding region of the receptor; of these, 8 represent synonymous SNPs, indicating that CHRM1 is highly conserved in humans. | →View more information from publications. |
Recent Publications on CHRM1: |  |
Characterization of a CNS penetrant, selective M1 muscarinic receptor agonist, 77-LH-28-1.
BACKGROUND AND PURPOSE: M1 muscarinic ACh receptors (mAChRs) represent an... | 3rd October, 2008
| Psychiatry Centre of Excellence for Drug Discovery, GlaxoSmithKline,
| Br J Pharmacol. 2008 Jul;154(5):1104-15. Epub 2008 May 5.
DOI Direct Link |
Benzamide protects delayed neuronal death and behavioural impairment in a mouse model of global cerebral ischemia.
The present study is aimed at evaluating the functional and... | 1st October, 2008
| Dr. B.R. Ambedkar Center for Biomedical Research, University of Delhi,
| Behav Brain Res. 2008 Oct 10;192(2):178-84. Epub 2008 Apr 8.
DOI Direct Link |
Levels of [(3)H]pirenzepine binding in Brodmann's area 6 from subjects with schizophrenia is not associated with changes in the transcription factor SP1 or BACE1.
Decreased muscarinic M1 receptor (CHRM1) mRNA has been reported in... | 16th September, 2008
| The Rebecca L. Cooper Research Laboratories, The Mental Health Research
| Schizophr Res. 2008 Sep 12.
DOI Direct Link |
Distinct pathways of ERK activation by the muscarinic agonists pilocarpine and carbachol in a human salivary cell line.
Cholinergic-muscarinic receptor agonists are used to alleviate mouth... | 18th July, 2008
| Department of Dental Diagnostic Science, University of Texas Health
| Am J Physiol Cell Physiol. 2008 Jun;294(6):C1454-64. Epub 2008 Apr 2.
DOI Direct Link |
Decreased cortical muscarinic receptors define a subgroup of subjects with schizophrenia.
Schizophrenia is widely acknowledged as being a syndrome, consisting of an... | 5th March, 2008
| [1] 1Centre for Neuroscience, The University of Melbourne, Parkville, VIC,
| Mol Psychiatry. 2008 Mar 4.
DOI Direct Link |
→View more research publications. |
CHRM1 results (if any) from reagent suppliers | 
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CHRM1 cholinergic receptor, muscarinic 1
HPA014101, Anti-CHRM1 antibody produced in rabbit Prestige Antibodies™ Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol ...
https://www.sigmaaldrich.com/catalog/search/SIRNASearchGeneD...
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Chrm1 cholinergic receptor, muscarinic 1
Chrm1; CHRM1. Refseq ID(s). NM_080773. Other Designations. Cholinergic receptor, muscarin 1; M1 muscarinic acetylcholine receptor; m1 muscarinic ...
http://www.sigmaaldrich.com/catalog/search/SIRNASearchGeneDe...
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BIOMOL International, LP - Anti-m1 Muscarinic Receptor ...
Anti-m1 Muscarinic Receptor (Cholinergic Muscarinic Receptor 1, Chrm1, Acetylcholine Muscarinic Receptor 1). + · Cannabinoids · Carbon Monoxide ...
http://www.biomol.com/?pageId=38&categoryId=964&productId=33...
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mAChR M1 (H-120) Antibody sc-9106
Number. Human, CHRM1, 1128, 11q12.3, NM_000738 · P11229 · 118510. Mouse, Chrm1, 12669, 19 A, P12657, N/A. Ordering Information ...
http://www.scbt.com/datasheet-9106-machr-m1-h-120-antibody.h...
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Antibodies to Neurotransmitter Receptors
CHRM1(1128), human, rat, IHC, IP, WB CL. M9558, Anti-Muscarinic Acetylcholine Receptor (M2) antibody produced in rabbit, affinity isolated antibody ...
http://www.sigmaaldrich.com/catalog/search/TablePage/9675634...
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mAChR M1 siRNA (h) sc-35829
ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, CHRM1, 1128, 11q12.3, NM_000738 · P11229 ...
http://www.scbt.com/datasheet-35829-machr-m1-sirna-h.html...
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MembraneMax™ Protein Expression kits
UNQ1887 (BC025781.1), 0.30. SPPL2B (BC001788.1), 0.30. CHRM2 (NM_000739.2), 0.30 . CHRM1 (NM_000738.2), 0.27. PPAPDC1B (NM_032483.2), 0.20 ...
http://www.invitrogen.com/site/us/en/home/Products-and-Servi...
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mAChR M1 siRNA (m) sc-35830
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Chrm1, 12669, 19 A, P12657 ...
http://www.scbt.com/datasheet-35830-machr-m1-sirna-m.html...
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MALDI-TOF-MS as a Tool In Prokaryotic Identification Laminin I ...
Cholinergic receptor, muscarinic 1, CNS:Chrm1,12669 OR. muscarinic 2, cardiac: Chrm2,107850 OR. muscarinic 3, cardiac:Chrm3,12671. 266-6. CRL-2151 ...
http://www.atcc.org/Portals/1/Pdf/atccv24no1.pdf...
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MembraneMax Protein Expression Kits
Melanocortin 5 r. eceptor (NM_005913). CRHR1 (NM_004382). HTR1A (NM_000524). CHRM1 (NM_000738). b2 adr. ener. gic r. eceptor (NM_000024) ...
http://www.invitrogen.com/etc/medialib/en/filelibrary/protei...
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